Dalit Levy

Zefat Academic College, Community Information Systems, Faculty Member

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Address: Israel

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Jens Allmer

Hochschule Ruhr West

İlhan Acar

Malik Yousef

Müşerref Duygu Saçar Demirci

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Alisha Parveen

Rituparno Sen

Helmholtz Centre for Infection Research

Spiros Likothanassis

University of Patras

Md. Eamin Rahman

Shahjalal University of Science and Technology

Edmund J Stellwag

East Carolina University

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Papers by Dalit Levy

Categorization of species based on their microRNAs employing sequence motifs, information-theoretic sequence feature extraction, and k-mers

EURASIP Journal on Advances in Signal Processing, 2017

Background: Diseases like cancer can manifest themselves through changes in protein abundance, an... more Background: Diseases like cancer can manifest themselves through changes in protein abundance, and microRNAs (miRNAs) play a key role in the modulation of protein quantity. MicroRNAs are used throughout all kingdoms and have been shown to be exploited by viruses to modulate their host environment. Since the experimental detection of miRNAs is difficult, computational methods have been developed. Many such tools employ machine learning for pre-miRNA detection, and many features for miRNA parameterization have been proposed. To train machine learning models, negative data is of importance yet hard to come by; therefore, we recently started to employ pre-miRNAs from one species as positive data versus another species' pre-miRNAs as negative examples based on sequence motifs and k-mers. Here, we introduce the additional usage of information-theoretic (IT) features. Results: Pre-miRNAs from one species were used as positive and another species' pre-miRNAs as negative training data for machine learning. The categorization capability of IT and k-mer features was investigated. Both feature sets and their combinations yielded a very high accuracy, which is as good as the previously suggested sequence motif and k-mer based method. However, for obtaining a high performance, a sufficiently large phylogenetic distance between the species and sufficiently high number of pre-miRNAs in the training set is required. To examine the contribution of the IT and k-mer features, an information gain-based feature ranking was performed. Although the top 3 are IT features, 80% of the top 100 features are k-mers. The comparison of all three individual approaches (motifs, IT, and k-mers) shows that the distinction of species based on their pre-miRNAs k-mers are sufficient. Conclusions: IT sequence feature extraction enables the distinction among species and is less computationally expensive than motif calculations. However, since IT features need larger amounts of data to have enough statistics for producing highly accurate results, future categorization into species can be effectively done using k-mers only. The biological reasoning for this is the existence of a codon bias between species which can, at least, be observed in exonic miRNAs. Future work in this direction will be the ab initio detection of pre-miRNA. In addition, prediction of pre-miRNA from RNA-seq can be done.

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Keeping in Touch: Tablets Use by Older Adults

by Elena Simonovsky and Dalit Levy

This article is based on a qualitative research conducted during 2012-2013, documenting the proce... more This article is based on a qualitative research conducted during 2012-2013, documenting the process of adjustment to tablet computers by males and females aged 65+. The purpose of the study was to characterize the lifestyle of the population commonly called "the Third Age" regarding the use of touch-screen technology. From an analysis of the data accumulated through ethnographic observations in the homes of the participants and through in-depth interviews with them, a multilayered model emerged, including four dimensions relevant to living with a tablet at the third age: Activity, Learning, Independence, and Barriers. This led to proposing a new model of aging which combines extensive use of devices with integrated touch-screen technology, referred to as "Aging Model 2.0". The research suggests that the use of advanced technology may contribute to a new representation of older adults in society, which, in turn, may lead us to reevaluate our relationship with our parents and grandparents.

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Computer science education as part of an undergraduate program in community information systems

2013 IEEE Frontiers in Education Conference (FIE), 2013

Recursively speaking

ACM SIGCSE Bulletin, 2000

„It's just like the whole picture, but smaller “: Expressions of gradualism, self-similarity, and othe pre-conceptions while classifying recursive phenomena

... studying computer science, both at the college and high school levels, yet the literature har... more ... studying computer science, both at the college and high school levels, yet the literature hardly refers to the latter (Ben-Ari 1997 is ... For example, the function 'Ronen' takes the function 'Jonathan' and adds one, but the function 'Jonathan' takes the function say, 'Alfonso' That's ...

ImplementingConstructivist Ideas in a Functional Programming Curriculum for Secondary School Students

‘PROGRAM BY DESIGN’ AS PART OF A NEW MAJOR IN COMMUNITY INFORMATION SYSTEMS

Recursively speaking

Proceedings of the thirty-first SIGCSE technical symposium on Computer science education - SIGCSE '00, 2000

Reoursion is a powerful concept, appearing in almost every introductory course in computer-soienc... more Reoursion is a powerful concept, appearing in almost every introductory course in computer-soience (CS). CS ocbwators and eda~cational researohets often refer to diff;oulties in learning recursion, and suggest methods for toaohing recursion. However, the researoh literature barely addresses the unique ways in whioh students relate to this intcrdisciplinmy conoept and the particular learners' language exm~ning reoursive phenomena. The gap is most apparent when seen through a constmctivist lens, where the students' prior knowledge and idiosyncratic conceptions should be referred to and reflected upon in order to serve as a basis for further knowledge construction. This paper reports on a study in which a collaborative classification of several recursive phenomena is used to facilitate the construction of recursion. The students' discourse was analyzed, as a step toward understanding the students" ways of speaking reeursively. Preliminary results indicate some basic aspects of recursion in the student discourse, although the students appanmtly talk a very different lansuag a fi'orn that of the experts, as used by books and tmohcrs.

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The Principle of Pattern-Oriented Curriculum and Its Implementation in a Computer Science Module for High School Students

2005 IEEE Symposium on Visual Languages and Human-Centric Computing (VL/HCC'05), 2005

An approach to the teaching and learning of high school computer science (CS) to and by education... more An approach to the teaching and learning of high school computer science (CS) to and by educationally disadvantaged students (EDS) is described. We begin by outlining six pedagogical principles for designing learning environments appropriate for EDS. Then, the implementation of one of these principles is presented. Results from years of using the CS module developed based on these principles in Israeli schools show that at the end of the module, the students master basic programming tools and recognize basic algorithmic patterns. These findings indicate the potential contribution of the approach outlined here for EDS.

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Links between Dynamic Representations of Atomic-Scale Phenomena and Molecular Reasoning

This paper reports the results of a study aimed at exploring the advantages of dynamic visualizat... more This paper reports the results of a study aimed at exploring the advantages of dynamic visualizations for the development of better understanding of molecular processes. During the spring and the fall of 2006, six hundred students learned about phases of matter and phase change using TELS 1 online chemistry curriculum. The curriculum utilizes Molecular Workbench 2 dynamic molecular models of solid, liquid, and gas, and scaffolds the learners' interactions with these dynamic representations by embedded reflective prompts to help make and refine connections between observable phenomena and atomic level processes related with phase change. The explanations that students entered in response to pre/post assessments items have been analyzed using a newly developed scale for measuring the level of molecular reasoning. Results indicate that from pre-test to post-test, students make progress in their level of molecular reasoning, and are better able to connect intermolecular forces and p...

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Shared terminology, private syntax

ACM SIGCSE Bulletin, 2002

This paper reports a study in which 11th grade students were observed, while engaged in several l... more This paper reports a study in which 11th grade students were observed, while engaged in several learning activities that address general aspects of recursion. One of these learning activities focused on the creation of recursive descriptions using natural language. The class discourse was recorded and analyzed, in order to locate patterns of students&amp;#x27; expressions and ways of thinking. The present finding is two-fold. On the one hand, a class genre was created and used to refer to recursive phenomena and to describe them verbally. On the other hand, although they used a shared set of some agreed-upon terms, the students tended to individually construct their unique recursive descriptions. These individual methods of assembly are labeled hereafter as &amp;quot;private syntax&amp;quot;. It is concluded that learners&amp;#x27; and educators&amp;#x27; awareness of both the &amp;quot;building blocks&amp;quot; of any recursive description and the several possibilities for assembling these blocks, might help in the process of understanding recursion in general and in further construction of recursive functions in particular.

Women, Hi-tech, and the Family-Career Conflict

Shopping Cart | Login | Register, IGI Global. BOOKS Book Information. Catalogs Imprints Book Seri... more

Implementing a new Computer Science Curriculum for middle school in Israel

2012 Frontiers in Education Conference Proceedings, 2012

ACM's Attention ot Women in IT

Shopping Cart | Login | Register, IGI Global. BOOKS Book Information. Catalogs Imprints Book Seri... more

It's just like the whole picture, but smaller': Expressions of gradualism, self- similarity, and other pre-conceptions while classifying recursive phenomena

Recursion is a key concept, appearing in almost every introductory course in computer-science. Ed... more Recursion is a key concept, appearing in almost every introductory course in computer-science. Educators and researchers often refer to difficulties in learning and teaching recursion. However, the research literature barely addresses the unique ways in which students relate to this interdisciplinary concept and the particular learners' language concerning recursive phenomena. The gap is most apparent when seen through a constructivist

Introducing computer science to educationally disadvantaged high school students

Research in Science & Technological Education, 2005

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How Dynamic Visualization Technology can Support Molecular Reasoning

Journal of Science Education and Technology, 2013

Collaborative Conceptual Change: The Case of Recursion

Journal of Intelligent Systems, 2000

Introducing computer science to educationally disadvantaged high school students -the Israeli experience

The social and educational issue of making the discipline of computer science accessible to the p... more The social and educational issue of making the discipline of computer science accessible to the public, including high school students who grow up in low socio-economic status families and in rural areas, have been shaping our thinking for over a decade. In the phrase "our thinking" I refer to the Israeli community of computer science (CS) educators, educational researchers and

Insights and Conflicts in Discussing Recursion: A Case Study

Computer Science Education, 2001

... Dalit Levy Department of Education in Science and Technology, Technion-Israel Institute of Te... more

Categorization of species based on their microRNAs employing sequence motifs, information-theoretic sequence feature extraction, and k-mers

EURASIP Journal on Advances in Signal Processing, 2017

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Keeping in Touch: Tablets Use by Older Adults

by Elena Simonovsky and Dalit Levy

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Computer science education as part of an undergraduate program in community information systems

2013 IEEE Frontiers in Education Conference (FIE), 2013

Recursively speaking

ACM SIGCSE Bulletin, 2000

„It's just like the whole picture, but smaller “: Expressions of gradualism, self-similarity, and othe pre-conceptions while classifying recursive phenomena

ImplementingConstructivist Ideas in a Functional Programming Curriculum for Secondary School Students

‘PROGRAM BY DESIGN’ AS PART OF A NEW MAJOR IN COMMUNITY INFORMATION SYSTEMS

Recursively speaking

Proceedings of the thirty-first SIGCSE technical symposium on Computer science education - SIGCSE '00, 2000

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The Principle of Pattern-Oriented Curriculum and Its Implementation in a Computer Science Module for High School Students

2005 IEEE Symposium on Visual Languages and Human-Centric Computing (VL/HCC'05), 2005

Download

Links between Dynamic Representations of Atomic-Scale Phenomena and Molecular Reasoning

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Shared terminology, private syntax

ACM SIGCSE Bulletin, 2002

Women, Hi-tech, and the Family-Career Conflict

Shopping Cart | Login | Register, IGI Global. BOOKS Book Information. Catalogs Imprints Book Seri... more

Implementing a new Computer Science Curriculum for middle school in Israel

2012 Frontiers in Education Conference Proceedings, 2012

ACM's Attention ot Women in IT

Shopping Cart | Login | Register, IGI Global. BOOKS Book Information. Catalogs Imprints Book Seri... more

It's just like the whole picture, but smaller': Expressions of gradualism, self- similarity, and other pre-conceptions while classifying recursive phenomena

Introducing computer science to educationally disadvantaged high school students

Research in Science & Technological Education, 2005

Download

How Dynamic Visualization Technology can Support Molecular Reasoning

Journal of Science Education and Technology, 2013

Collaborative Conceptual Change: The Case of Recursion

Journal of Intelligent Systems, 2000

Introducing computer science to educationally disadvantaged high school students -the Israeli experience

Insights and Conflicts in Discussing Recursion: A Case Study

Computer Science Education, 2001

... Dalit Levy Department of Education in Science and Technology, Technion-Israel Institute of Te... more

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