Papers by Ezgi Soncu Büyükişcan
Experimental aging research, Mar 28, 2024
Archives of Neuropsychiatry
Alzheimers & Dementia, Jul 1, 2018
Vera M. Mendes, Naomi De Roeck, Javier S aez-Valero, Eduard A. Struys, Kees WJ. van Uffelen, Euge... more Vera M. Mendes, Naomi De Roeck, Javier S aez-Valero, Eduard A. Struys, Kees WJ. van Uffelen, Eugeen Vanmechelen, Ulf Andreasson, Charlotte E. Teunissen, Alzheimer Center and Department of Neurology, Amsterdam Neuroscience, VU University Medical Center, Amsterdam, Netherlands; Institute Born-Bunge, Wilrijk, Belgium; Instituto de Neurociencias de Alicante, Universidad Miguel Hern andez-CSIC, Sant Joan d’Alacant, Spain; VUmc, Amsterdam, Netherlands; Institute Born-Bunge, University of Antwerp, Antwerp, Belgium; Reference Center for Biological Markers of Dementia, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium; VU University Medical Center, Amsterdam, Netherlands; VU University Medical Center Amsterdam, Amsterdam, Netherlands; Universidad Miguel Hern andez-CSIC, Alicante, Spain; University of Coimbra, Coimbra, Portugal; Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal; Reference Center for Biological Markers of Dementia, Laboratory of Neurochemistry and Behavior, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium; Instituto de Neurociencias de Alicante, Universidad Miguel Hern andez-CSIC, Sant Joan d’Alacant, Spain; Department of Biochemistry, VU University Medical Center, Amsterdam Neuroscience, Amsterdam, Netherlands; ADx NeuroSciences NV, Technologiepark, Ghent, Belgium; Institute of Neuroscience and Physiology, The Sahlgrenska Academy at University of Gothenburg, M€olndal, Sweden; Neurochemistry Laboratory and Biobank, Department of Clinical Chemistry, Amsterdam Neuroscience, VU University Medical Center, Amsterdam, Netherlands. Contact e-mail: [email protected]
Alzheimers & Dementia, Jul 1, 2018
Alzheimers & Dementia, Jul 1, 2017
Alzheimers & Dementia, Jul 1, 2017
Alzheimer's & Dementia, 2017
European Psychiatry, 2012
Introduction: Various personal and sociocultural factors such as gender, age, socioeconomic statu... more Introduction: Various personal and sociocultural factors such as gender, age, socioeconomic status, and attachment style are suggested to affect coping styles of individuals (e.g. Greenberger and McLaughlin, 1998; Seiffge-Krenke, 2006). Aim: The present study aims to investigate variables related to different coping styles (seeking external help, turning to religion, avoidance [emotional-behavioral, and biochemical], active planning, acceptance and cognitive restructuring) among a group of young adults in Turkey. Method: 105 undergraduate students from a private university in Istanbul participated in the study and filled out the questionnaires. The questionnaires consisted of a demographical form, Relationship Scales Questionnaire (Griffin & Bartholomew, 1994), and Coping Questionnaire (Ozbay, 1993). Results: Regressional analyses revealed the following results: 1) Preoccupied attachment score and the amount of time spent for social activities were significant predictors of seeking external help. 2) In terms of turning to religion, preoccupied attachment score, number of siblings, and the amount of time spent for social activities were identified as significant predictors. 3) Fearful attachment style and loss of mother significantly predicted emotional-behavioral avoidance. 4) Regarding avoidance through using biochemical substances, current GPA and the amount of time spent for social activities were found as statistically significant predictors. Conclusion: Attachment style was noted as the most important predictor of coping styles of young adults. Accordingly, the implications of these findings in terms of both social well-being and academic life were discussed together with recommendations for intervention strategies on both individual and group levels.
Alzheimer's & Dementia, 2017
Anders Wallin, Alberto Lle o, Julius Popp, Pablo Martinez-Lage, Stuart G. Snowden, Cristina Legid... more Anders Wallin, Alberto Lle o, Julius Popp, Pablo Martinez-Lage, Stuart G. Snowden, Cristina Legido-Quigley, Lars Bertram, Frederik Barkhof, Henrik Zetterberg, Johannes Streffer, Pieter Jelle Visser, Simon Lovestone, University of Oxford, Oxford, United Kingdom; King’s College London, London, United Kingdom; Maastricht University, Maastricht, Netherlands; Alzheimer Center Limburg, Maastricht University, Maastricht, Netherlands; University Hospital Leuven, Leuven, Belgium; Alzheimer Center, VU University Medical Center, Amsterdam, Netherlands; University of Antwerp, Antwerp, Belgium; Department of Neurology and Memory Clinic, Hospital Network Antwerp (ZNA) Middelheim and Hoge Beuken, Antwerp, Belgium; University of Geneva, Geneva, Switzerland; Alzheimer’s Disease Unit and Other Cognitive Disorders Unit, Hospital Clinic de Barcelona, Barcelona, Spain; Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, M€olndal, Sweden; Hospital de la Santa Creu i Sant Pau, Barcelona, Spain; University Hospital Lausanne, Lausanne, Switzerland; Fundaci on CITA-Alzh eimer Fundazioa, San Sebastian, Spain; University of L€ubeck, L€ubeck, Germany; Department of Radiology and Nuclear Medicine, Amsterdam Neuroscience, VU University Medical Center, Amsterdam, Netherlands; University of Gothenburg, Gothenburg, Sweden; University College London, London, United Kingdom; Janssen Research & Development, Beerse, Belgium; VU University Medical Center, Amsterdam, Netherlands. Contact e-mail: sarah. [email protected]
Journal of Neuropsychology, 2020
Although cognitive theory of mind (ToM) has been largely studied within neurodegenerative disorde... more Although cognitive theory of mind (ToM) has been largely studied within neurodegenerative disorders including Alzheimer's disease (AD), studies focusing on affective ToM are relatively limited, yielding inconsistent findings. The current study aimed at investigating affective ToM abilities within different stages of AD (mild AD dementia [ADD], mild cognitive impairment [MCI], and subjective cognitive impairment [SCI]), together with its relationship with neuropsychological functioning. Eighty-one participants were tested with two different ToM tasks (Faux Pas Recognition Test [FPR] and Reading Mind in the Eyes Test [RMET]) and tests of attention, executive functions, episodic memory, and facial recognition. Our results showed two different affective ToM profiles in AD continuum: while ADD group performed poorly on both tasks of ToM, MCI group displayed deteriorated performance on RMET but not on FPR. In addition, ToM performance was significantly related to episodic memory and verbal fluency within the overall sample. These findings suggest that impairment in the decoding process of emotional cues could begin even in the prodromal stage of AD. In contrast, the reasoning process of emotional information, as measured with FPR, could be preserved until the dementia stage. Moreover, the relation of affective ToM with amnestic functions and verbal abilities could provide evidence of a domain-general ToM impairment in AD. Premack and Woodruff (1978) introduced the term 'theory of mind (ToM)' to refer to the ability of an individual to understand the mental states of oneself and others. Since then, several studies have investigated different aspects of ToM, including its cognitive and neural mechanisms, among healthy and clinical populations. Although there is not yet a consensus on whether ToM is an independent social cognitive function or is interrelated with other cognitiveparticularly executivefunctions, recent evidence appears to be in
The main purpose of this study was to investigate mental health profiles, attachment styles, and ... more The main purpose of this study was to investigate mental health profiles, attachment styles, and burnout among mental health professionals in Turkey. A sample of 245 professionals including psychologists, psychiatrists, counselors, social workers and other mental health professionals filled out the questionnaire. The public link of the survey, together with an introductory statement about the content and purpose of the study, was sent to major email groups joined by mental health professionals. The survey was also converted into a Word format, printed and distributed to major hospitals and counseling and psychotherapy clinics in Istanbul. The findings showed that mental health professionals in Turkey are psychologically healthier than normal comparisons. They also displayed a higher frequency of secure attachment together with a lower frequency of insecure attachment compared to the general population. Contrary to expectations, burnout was not experienced by the sample. Attachment s...
Turkish Journal of Psychiatry, 2019
Alzheimer hastalığı (AH) beyinde yapısal ve işlevsel değişimler meydana getiren nörodejeneratif b... more Alzheimer hastalığı (AH) beyinde yapısal ve işlevsel değişimler meydana getiren nörodejeneratif bir hastalıktır. Gelişen beyin görüntüleme yöntemleri sayesinde AH patolojisine eşlik eden yapısal ve işlevsel bağlantılardaki bozulmalar gitgide daha görünür hale gelmiştir. AH'de dinlenim durumu bağlantısallığında, özellikle de olağan durum ağı (default mode network-DMN) olarak adlandırılan içsel bağlantısallık ağında farklılaşmalar görülmektedir. Bu çalışmada DMN bağlantısallık bulgularının incelenmesi ve tartışılması amaçlanmıştır. Yöntem: İşlevsel manyetik rezonans görüntüleme (fMRI) çalışmalarında en yaygın kullanılan 2 temel metodoloji (tohum temelli ve bağımsız bileşen analizi) temel alınarak alanda yapılan çalışmalar incelenmiştir. Bulgular: Çalışmalar genel olarak, DMN bağlantısallığının AH süreci boyunca ilerleyici bir şekilde bozulduğunu göstermektedir. DMN alt sistemlerinin AH'nin preklinik ve prodromal evrelerinde farklı bağlantısallık örüntüleri gösterdiği de belirtilmektedir. DMN'deki bozulmanın diğer bağlantısallık ağlarındaki farklılaşma ile ilişkili olabileceğini öne süren kanıtlar da mevcuttur. Buna ek olarak, bulgular DMN'nin AH ile ilişkili nöropatoloji ve genetik risk faktörleri ile olan ilişkisine de işaret etmektedir. Sonuç: AH'nin beyinde başta DMN olmak üzere diğer dinlenim durumu ağlarında işlevsel bozulmalara yol açan yaygın bir diskonneksiyon sendromu olduğu öne sürülebilir. Buna ek olarak, preklinik vakalarda ve risk taşıyan kişilerde de saptanabilen AH ile ilişkili işlevsel bağlantısallık değişimleri AH için muhtemel bir biyo-belirteç olabilir.
Aging, Neuropsychology, and Cognition, 2019
ABSTRACT Theory of Mind (ToM) refers to the ability to make inferences on other’s mental or emoti... more ABSTRACT Theory of Mind (ToM) refers to the ability to make inferences on other’s mental or emotional states. Although there is evidence suggesting that impaired executive functions due to aging could have a negative impact on cognitive ToM, there is still controversy about the effect of age and age-related executive dysfunctions on affective ToM. To investigate affective ToM in healthy aging and its relationship with executive functions, we examined Reading Mind in the Eyes Test (RMET) performance and executive functions among young and older adults. There was no significant difference between age groups regarding their RMET scores. While affective ToM was correlated to executive functioning within the younger group, short term memory was found to be associated with RMET performance among older participants. Furthermore, within the older group, women performed better than men. Our findings suggest a preserved ability of affective ToM in healthy aging, which appears to be independent of executive functioning.
Psikoloji Çalışmaları / Studies in Psychology, 2018
ÖZ Çocukluk amnezisi, gelişimin erken evrelerinde üretilen otobiyografik anıların yetişkinlik dön... more ÖZ Çocukluk amnezisi, gelişimin erken evrelerinde üretilen otobiyografik anıların yetişkinlik döneminde tam olarak hatırlanamaması olarak tanımlanan bir durumdur. Genel olarak hatırlanan ilk anıların ortalama 34 yaşa ait olduğu kabul edilse de, ilk çocukluk anısının ait olduğu yaş tartışmalıdır. Bu çalışmada genç yetişkinlerde hatırlanan ilk çocukluk anısına ait yaşın belirlenmesi ve cinsiyet, anıya ilişkin faktörler, bağlanma stilleri ve çocukluk çağı travmatik olaylarının anı yaşı üzerindeki etkisinin incelenmesi amaçlanmıştır. Araştırmaya 137 üniversite öğrencisi katılmıştır. Katılımcılardan hatırladıkları ilk anıyı yazmaları ve anının yaşı ile sıradanlık düzeyi, netliği, emosyonel yoğunluğu, bütünlüğü gibi anı özelliklerini değerlendiren anketi doldurmaları istenmiştir. Buna ek olarak katılımcıların erken travmatik deneyimleri ve bağlanma stilleri de değerlendirilmiştir. Katılımcıların hatırladıkları ilk çocukluk anısına ait yaşın 24 ve 95 ay arasında değiştiği ve ortalamanın 52.44 (SS = 16.77) ay olduğu bulunmuştur. Kadın katılımcılarda ilk anı yaşının erkek katılımcılara kıyasla anlamlı düzeyde daha düşük olduğu saptanmıştır. Cinsiyete ek olarak, çocukluk çağında yaşanan ebeveynler arasındaki ilişkiye dair travmatik olayların varlığı ilk anı yaşı ile ilişkili bir diğer faktör olarak ön plana çıkmıştır. Çocukluk çağı amnezisi otobiyografik belleğin ortaya çıkışının bir işareti olarak düşünülmektedir. Bulgular cinsiyet gibi bireysel özelliklere ek olarak erken çocukluk çağı deneyimlerinin çocukluk çağı amnezisi ile ilişkili olduğunu öne sürmektedir. Anahtar Kelimeler: Bellek, çocukluk çağı, amnezi 1Dr. Öğr. Üyesi, Işık Üniversitesi, Fen Edebiyat Fakültesi, Psikoloji Bölümü, İstanbul, Türkiye 2Dr. Öğr. Üyesi, Yeditepe Üniversitesi, Fen Edebiyat Fakültesi, Psikoloji Bölümü, İstanbul, Türkiye 3Psikolog, Işık Üniversitesi, Fen Edebiyat Fakültesi, Psikoloji Bölümü, İstanbul, Türkiye
International Journal of Psychological Studies, 2018
Young adulthood is a period that requires serious transitions. Psychological adjustment during th... more Young adulthood is a period that requires serious transitions. Psychological adjustment during this period might be an important contributor to academic as well as social wellbeing. This study aims at identifying factors that predict psychological adjustment among university students in Turkey. Attachment style and coping strategies were suggested as possible predictors. The data was gathered from 105 undergraduate students. The results reveal attachment and coping styles as significant predictors for psychological adjustment. Implications of the findings are discussed in an attempt to foster better psychological adjustment among young adults.
Turkish Journal Of Neurology
Cocukluk amnezisi, gelisimin erken evrelerinde uretilen otobiyografik anilarin yetiskinlik donemi... more Cocukluk amnezisi, gelisimin erken evrelerinde uretilen otobiyografik anilarin yetiskinlik doneminde tam olarak hatirlanamamasi olarak tanimlanan bir durumdur. Genel olarak hatirlanan ilk anilarin ortalama 3- 4 yasa ait oldugu kabul edilse de, ilk cocukluk anisinin ait oldugu yas tartismalidir. Bu calismada genc yetiskinlerde hatirlanan ilk cocukluk anisina ait yasin belirlenmesi ve cinsiyet, aniya iliskin faktorler, baglanma stilleri ve cocukluk cagi travmatik olaylarinin ani yasi uzerindeki etkisinin incelenmesi amaclanmistir. Arastirmaya 137 universite ogrencisi katilmistir. Katilimcilardan hatirladiklari ilk aniyi yazmalari ve aninin yasi ile siradanlik duzeyi, netligi, emosyonel yogunlugu, butunlugu gibi ani ozelliklerini degerlendiren anketi doldurmalari istenmistir. Buna ek olarak katilimcilarin erken travmatik deneyimleri ve baglanma stilleri de degerlendirilmistir. Katilimcilarin hatirladiklari ilk cocukluk anisina ait yasin 24 ve 95 ay arasinda degistigi ve ortalamanin 52....
Journal of Clinical Neuroscience
International Journal of Psychological Studies, 2018
Young adulthood is a period that requires serious transitions. Psychological adjustment during th... more Young adulthood is a period that requires serious transitions. Psychological adjustment during this period might be an important contributor to academic as well as social wellbeing. This study aims at identifying factors that predict psychological adjustment among university students in Turkey. Attachment style and coping strategies were suggested as possible predictors. The data was gathered from 105 undergraduate students. The results reveal attachment and coping styles as significant predictors for psychological adjustment. Implications of the findings are discussed in an attempt to foster better psychological adjustment among young adults.
Childhood amnesia is a state which is characterized by an inability to fully remember autobiograp... more Childhood amnesia is a state which is characterized by an inability to fully remember autobiographical memories formed in the early stages of development. Although it is generally accepted that the earliest memories belong to the ages of 3 or 4, the exact age to which the first childhood memory belongs is still debatable. This study aims to identify the age of a first childhood memory, and to investigate the effects of gender, factors related to that memory, attachment style and childhood traumatic experiences on the age of first memory. A total of 137 university students participated in the study. Participants were asked to write down their first memory and fill out a survey that asked for the age and features of the memory such as the level of ordinariness, clarity, emotional intensity, and integrity. In addition, participants’ early traumatic experiences and attachment styles were assessed. The results indicated that the age to which first memory belongs ranges between 24 and 95 months, with a mean of 52.44 (SD = 16.77) months. The age of the earliest memory was significantly younger for women compared to men. In addition to gender, early traumatic experiences related to parents’ relationships emerged as another significant predictor of the age of the earliest memory. Childhood amnesia is perceived as an indicator of the development of autobiographical memory. Our findings suggest that in addition to personal characteristics such as gender, childhood amnesia is also related to early childhood experiences.
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Papers by Ezgi Soncu Büyükişcan