Tony Kulesa (@kulesatony) / X

Tony Kulesa

4,087 posts

Tony Kulesa

@kulesatony

biotech startups @pillar_vc, ai for science @encode_pillarvc founding team @EdisonSci Prior: @petribio @MIT, @BroadInstitute

Joined April 2021

Tony Kulesa
@kulesatony
Mar 17, 2025
New review out today in Nature Biotech on nanopore-based protein sequencing. Feels... like... something... coming... soon... 👀
61K
Tony Kulesa
@kulesatony
Nov 5, 2025
I finished my PhD with more questions than answers. I had built huge screening datasets, there was just too much data to explore. The first thing I did when I got access to Kosmos was throw in some of these datasets. Honestly, my jaw dropped at the result. Try it yourself:
Sam Rodriques
@SGRodriques
Nov 5, 2025
Today, we’re announcing Kosmos, our newest AI Scientist, available to use now. Users estimate Kosmos does 6 months of work in a single day. One run can read 1,500 papers and write 42,000 lines of code. At least 79% of its findings are reproducible. Kosmos has made 7 discoveries
00:00
151K
Tony Kulesa
@kulesatony
Oct 31, 2022
1/ At @pillar_vc, we’re open-sourcing all the knowledge and knowhow of building biotech companies. Today we’re launching the Founder-led Biotech Ecosystem – a curated, open-source set of community-built resources. And we want your contribution! founderledbio.com/ecosystem
Tony Kulesa
@kulesatony
Aug 18, 2021
The biotech startup ecosystem is dominated by a culture that requires every executive team to have done it before. Many companies are even created by VCs internally. But a new model is emerging -- the founder-led biotech. Why I think this is the future: pillar.vc/news/the-futur…
Tony Kulesa
@kulesatony
Sep 1, 2021
I’ve spent a decade cultivating a network of biotech's top emerging talent. In the past 2 years, I noticed that many of the best new people had already been discovered by someone else -- @tylercowen. I became obsessed with learning how he does it: kulesa.substack.com/p/tyler-cowen-…
Tony Kulesa
@kulesatony
Sep 27, 2024
Nanopore proteomics is beginning to break wide open. A mass spec on every bench, and as easy and ubiquitous as gels and blots.
44K
Tony Kulesa
@kulesatony
Jul 13, 2022
Replying to @andy23tran
A tale of two covariates: Why OWID and company are wrong about US healthcare
From randomcriticalanalysis.com
Tony Kulesa
@kulesatony
Oct 12, 2022
What is the best book for self-study of immunology?
Tony Kulesa
@kulesatony
Jun 13, 2021
If you are an academic, entrepreneur, or investor in biotech, the field is changing so fast that “it takes all the running you can do to keep in the same place.” The most important skill is learning quickly without expert guidance. My most important behaviors and tools: 1/
Tony Kulesa
@kulesatony
Mar 20, 2025
🚀 Fellowship applications are OPEN for Encode: AI for Science. What if you could use AI to - Design shape-shifting robots - See through solid materials - Decode language of the brain - Create advanced materials
00:00
67K
Tony Kulesa
@kulesatony
Jan 30, 2022
Scientists should capture more of the value they create.
Tony Kulesa
@kulesatony
Feb 11, 2025
Announcing Encode: AI for Science We're launching a fellowship powered by @ARIA_research to connect top AI talent with leading UK science labs to unlock the next wave of scientific breakthroughs.
00:00
65K
Tony Kulesa
@kulesatony
May 11, 2021
*Narrative Violation:* The largest biotech to go public in history is in synthetic biology, not therapeutics; is founder-led, not built by venture creation firms; and is run by first-time founders fresh from their PhDs, not seasoned pharma executives.
Jason Kelly
@jrkelly
May 11, 2021
Am considering taking @Ginkgo public😉 bloomberg.com/news/articles/…
Tony Kulesa
@kulesatony
Feb 3, 2022
Biotech is entering a new age. In the heyday of Bell Labs, wartime spurred not only rapid invention, but also raised ambitions to create “the most complex machine ever attempted.” At that time, the most complex machine was the universal phone system. Today, it is man itself.