Karthik Senthil (@karsenthil) / X

Karthik Senthil

14.7K posts

Karthik Senthil

@karsenthil

building // first-check investing in AI + crypto founders @806Capital // led eng + prod teams @amazon @circle // 2X founder // girl-dad X2

NYC

Joined March 2009

Pinned
Karthik Senthil
@karsenthil
Feb 11
NYC is full of people who should be founding generational companies. But unlike the Valley, our culture doesn't inspire irrational, ambitious swings. So I’m launching HOMERUNS: a hands-on sprint to help NYC builders go from crazy idea → v1 → company in 6 weeks👇
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Karthik Senthil
@karsenthil
Jan 1, 2025
Article
Crypto X AI Thesis (Part 1) -- We're at a "Step Function" Moment
AI represents the next step-function in the evolution of blockchains. Every era of blockchain evolution tends to follows a familiar arc: A step-function “order of magnitude” improvement catalyzes a...
179K
Karthik Senthil
@karsenthil
Apr 4, 2023
gm. I'm excited to share my Middleware Thesis. Why middleware will be the unexpected star of modular design, why vertical integration matters, and how it'll actually scale crypto to the proverbial next 1B consumers 👇 🧵 (1/21)
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Karthik Senthil
@karsenthil
Sep 9, 2024
gm. I'm super excited to more publicly share my new role at Matter Labs as the head of ZKsync Era. Some quick thoughts 👇
36K
Karthik Senthil
@karsenthil
Jun 15, 2021
Investing in crypto changed my life. I began investing in crypto (by chance) since 2017 and it's pushed my net worth to 7 figure status. Here's my immigrant story of how crypto helped me become wealthy - but not in the way you might think... 📖
Karthik Senthil
@karsenthil
Oct 6, 2024
Replying to @0xkrma
Zucks contribution to humanity is negative tho
60K
Karthik Senthil
@karsenthil
Jan 9, 2024
gm. I'm excited to share that I've started a new role as the product owner for @zksync 🫡🫡 IMO, the 10X unlock blockchains provide is enabling bi-directional value transfer at Internet scale. Transferring value using existing technology has meaningful constraints in the kind
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Karthik Senthil
@karsenthil
Jan 8, 2025
Article
Crypto X AI Thesis (Part 2) -- Opportunities for Builders and Investors
If you missed Part 1 of the thesis where we discuss why AI represents a step function moment for blockchains, please check it out here. So, Who Will The Big Winners Be? With AI unlocking innovation at...
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Karthik Senthil
@karsenthil
May 16, 2025
Some bittersweet news: this week is my last week at @zksync The last ~16 months have been an amazing journey filled with experiences I never imagined I'd have a chance to do in crypto including owning one of the industry's largest ecosystems in Era, driving one of the biggest
22K
Karthik Senthil
@karsenthil
Nov 19, 2024
gm. Much like DeFi or DePIN, I see a new category of crypto networks + capital formation emerging around its own primitive: user-owned data. I call this DeData. How ZK (incl zkTLS) enables this, how AI will use these networks, & why DeData apps will onboard users 🧵 (1/25)
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Karthik Senthil
@karsenthil
Dec 28, 2024
Looking for AI founders who want to build a cutting-edge DeFi agent. We at @zksync have a DeFi + RWA ecosystem that's about to pop (@ZKsyncIgnite launching in a week), and Im down to personally spend time with you + figure out how to get you funding. DMs open.
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Karthik Senthil
@karsenthil
Feb 1, 2024
ZK is the Endgame
ZKsync
@zksync
Feb 1, 2024
ZK is the Endgame
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Karthik Senthil
@karsenthil
Jul 23, 2024
The dydx playbook will become increasingly adopted by founders over time: 1. Launch app on existing L1/L2 to find PMF 2. Those who find PMF realize they don't control economics, blockspace, or UX. 3. Turbo-charge by moving to their own chain (ideally within same ecosystem)
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Karthik Senthil
@karsenthil
Dec 23, 2024
AI + ZK joining forces. Believe in something.
Eternal AI
@EternalAI_
Dec 23, 2024
We’ve teamed up with @zksync to bring Decentralized AI Agents to ZKsync Era! Now, anyone can launch a ZK Agent in just a few clicks: 1⃣ Go to eternalai.org, click "Create your AI Agent" 2⃣ Choose ZKsync Era at step 2 3⃣ Tailor agent's name & personality 4⃣ Activate it
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