eLife - the journal

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eLife - the journal

@eLife

The funder-researcher collaboration and open-access journal for research in the life and biomedical sciences | @eLifeCommunity

Cambridge, UK

elifesciences.org

Joined September 2011

eLife - the journal
@eLife
2h
Reprogramming of host energy metabolism mediated by the TNF-iNOS-HIF-1α axis plays a key role in host resistance to <i>Plasmodium</i> infection
elifesciences.org
Reprogramming of host energy metabolism mediated by the TNF-iNOS-HIF-1α axis plays a key role in...
TNF-driven metabolic reprogramming enhances glucose utilization in monocytes through inducible nitric oxide synthase (iNOS) and hypoxia-inducible factor 1α (HIF-1α), promoting parasite control and...
eLife - the journal
@eLife
7h
We’re hiring! Join us as Finance and Business Support Coordinator in our Finance and Operations team. If you’re organised, proactive and have practical finance experience, this is a great varied role at the heart of our day-to-day operations. elifesciences.org/jobs/6f8d6f8d/…
eLife - the journal
@eLife
7h
Active dendrites enable robust spiking computations despite timing jitter
elifesciences.org
Active dendrites enable robust spiking computations despite timing jitter
The brain computes rapidly and reliably using brief electrical impulses and likely exploits internal memory in nerve cells to achieve this more efficiently than existing computing hardware and neural...
eLife - the journal
@eLife
23h
An abundant merozoite surface protein of <i>Plasmodium falciparum</i> modulates susceptibility to inhibitory antibodies
elifesciences.org
An abundant merozoite surface protein of Plasmodium falciparum modulates susceptibility to inhibi...
Pathogens can use surface proteins to limit immune responses, and the finding that merozoite surface protein 2 has this property could help in Plasmodium falciparum malaria vaccine development.
eLife - the journal
@eLife
Aug 19
In-cell cryo-electron tomography reveals differential effects of type I and type II kinase inhibitors on LRRK2 filament formation and microtubule association
elifesciences.org
In-cell cryo-electron tomography reveals differential effects of type I and type II kinase inhibi...
Type I and type II inhibitors differentially affect LRRK2 filament formation around microtubules, revealing an important consideration for Parkinson’s disease drug development.