Benoit Lehallier (@blehall) / X

Benoit Lehallier

114 posts

Benoit Lehallier

@blehall

#Nonlinearthinker #Omicsaholic

California

researchgate.net/profile/Benoit…

Joined January 2012

Benoit Lehallier
@blehall
Apr 28
I’m excited to present Chronos at @KeystoneSymp Closing the #DiversityGap in Global #Genomics, Medicine and #PopulationHealth, kicking off today in Hannover! I’d love to connect - feel free to DM me to set up a 1:1 conversation. keysym.us/KSPopulationHe… #KSPopulationHealth26
Benoit Lehallier
@blehall
Mar 26
What if we could detect Parkinson's disease up more than a decade before symptoms appear? We just published results from Chronos-PD, leveraging a unique resource: 100+ million archived plasma samples from routine donations. Here's what we found 🧵
medrxiv.org
Early Parkinson’s Revealed by Unlocking Longitudinal Omics at Population Scale
Many diseases begin developing years before symptoms appear[1][1]–[3][2], yet biospecimens from these early stages are rarely available. We developed Chronos, a framework that uses privacy-preserving...
Benoit Lehallier
@blehall
Jan 14, 2025
Large-scale proteomics is unlocking in a new era of biomarker discovery and therapeutic target identification. #Chronos offers a unique opportunity: high-temporal-resolution profiling of 100 millions longitudinal plasma samples across pre-clinical phases of any disease (1/5)
Benoit Lehallier
@blehall
Sep 20, 2022
Preprint alert! A must read from Oliver Hahn who generated a spatiotemporal gene expression map of 15 brain regions! This study shows that the white matter tracts are an early hotspot of brain aging! Many other cool findings to discover here 👇
biorxiv.org
A spatiotemporal map of the aging mouse brain reveals white matter tracts as vulnerable foci
Aging is the key risk factor for loss of cognitive function and neurodegeneration but our knowledge of molecular dynamics across the aging brain is very limited. Here we perform spatiotemporal...
Benoit Lehallier
@blehall
Jan 23, 2022
Data from NIH-funded studies will have to be shared. This won't be straightforward to implement but that's a huge step for open science 👇
Florian Krammer
@florian_krammer
Jan 23, 2022
1) On January 25th 2023 a new data sharing policy from NIH kicks in which basically requires raw data from NIH-funded studies to be shared. Data is defined as:

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