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Magdalena Zernicka-Goetz
@ZernickaGoetz
Scientist @Cambridge & @Caltech trying to build life from stem cells to understand it better. The author of #TheDanceofLife. Warsaw/Cambridge/LA. Art @BBBPACK
Cambridge & Caltech
Joined May 2016
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    Magdalena Zernicka-Goetz
    @ZernickaGoetz
    Aug 2, 2022
    After building embryoids for 10 years, we succeeded in generating structures with brains, hearts, neural tubes, somites with a yolk sac. Both original submissions using two different approaches are on BioRxiv, to be published soon. eur03.safelinks.protection.outlook.com/?url=https%3A%…
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    Magdalena Zernicka-Goetz
    @ZernickaGoetz
    Aug 25, 2022
    Our paper is finally out! After 10 years of model building we generate complete embryoids from three types of stem cells - they develop heart, brain structures and more. We show the first proof of concept knocking out a gene required for neurodevelopment
    Content cover image
    Embryo model completes gastrulation to neurulation and organogenesis
    From nature.com
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    Magdalena Zernicka-Goetz
    @ZernickaGoetz
    May 13, 2024
    What is the origin of our body? Our paper @CellCellPress shows that when a human embryo is one day old and comprises just two cells, only one cell will create most of the fetus in addition to placenta, while the other cell will create placenta.
    The first two blastomeres contribute unequally to the human embryo
    From cell.com
    168K
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    Magdalena Zernicka-Goetz
    @ZernickaGoetz
    Oct 13, 2021
    We are hiring an expert in live embryo imaging! If you are interested in early mouse and human development and would like to look at it in a new way, please contact me.
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    Magdalena Zernicka-Goetz
    @ZernickaGoetz
    Jul 31, 2024
    As someone who’s been mentoring future PIs for a while, I often get asked how I choose post-docs for my lab and if I have a crystal ball for predicting their success. Well, here is the scoop: I don’t! But here are some things I look for: (1/8)
    197K
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    Magdalena Zernicka-Goetz
    @ZernickaGoetz
    Oct 6, 2020
    Happy and honoured to receive this year Pioneer Award @NIH. Very greatful to my @MZG_Lab, @Caltech, @Cambridge_Uni and my wonderful mentors John Gurdon and Martin Evans @GurdonInstitute
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    Magdalena Zernicka-Goetz
    @ZernickaGoetz
    Jan 21, 2022
    I’m deeply honored to be chosen to deserve Conklin Medal this year. Special thanks to my amazing team of brilliant scientists at @Caltech and @Cambridge_Uni @PDN_Cambridge
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    Society for Developmental Biology
    @SocDevBio
    Jan 21, 2022
    Congrats to Magdalena Zernicka-Goetz @ZernickaGoetz @Caltech @Cambridge on receiving the 2022 SDB Edwin G. Conklin Medal for illuminating mechanisms of early mammalian embryogenesis through innovative techniques culturing post-implantation stage embryos. bit.ly/3IgRMx4
    Magdalena Zernicka-Goetz
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    Magdalena Zernicka-Goetz
    @ZernickaGoetz
    Mar 14, 2021
    First Human Blastoids @Caltech. Our long journey from mouse to human - it is 7 years since our first mouse prototype was published. Thanks to the first authors @BernaSozen_ and my first PhD student @Caltech Victoria
    biorxiv.org
    Reconstructing human early embryogenesis in vitro with pluripotent stem cells
    Understanding human development is of fundamental biological and clinical importance. Yet despite its significance, insights into early developmental events in humans still remain largely unknown....
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    Magdalena Zernicka-Goetz
    @ZernickaGoetz
    Dec 30, 2020
    We are looking for postdoctoral colleague to study cell fate choices using lights sheet and 2photon imaging of mouse natural and stem cell-derived embryos in California @Caltech. If you are interested, pls send me a message. Please RT.
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    Magdalena Zernicka-Goetz
    @ZernickaGoetz
    Oct 7, 2025
    John Gurdon, whom we lost today, was not only my mentor but a dear friend. We met 30 years ago in Cambridge. He believed in me more than I believed in myself. His generosity, boundless curiosity, and sense of adventure shaped my life as a scientist 🖤 He will be missed by many.
    21K
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    Magdalena Zernicka-Goetz
    @ZernickaGoetz
    Sep 21, 2021
    Very happy I can finally share our experience with human blastoids. Beautiful morphology but EPES cells have limitations in lineage specification. Reconstructing aspects of human embryogenesis with pluripotent stem cells | Nature Communications nature.com/articles/s4146…
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    Magdalena Zernicka-Goetz
    @ZernickaGoetz
    Oct 20, 2023
    Finally we can share in full our long journey from mouse & human embryo implantation 10 years ago, through many mouse models, to this human embryo model. A decade long but a beautiful & fulfilling journey with wonderful people, too many to mention all here
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    Pluripotent stem cell-derived model of the post-implantation human embryo
    From nature.com
    44K
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    Magdalena Zernicka-Goetz
    @ZernickaGoetz
    May 7, 2020
    The role of basement membrane remodelling in embryo growth and - unexpectedly! - pre-pattering for gastrulation. Million thanks to my most wonderful colleagues @KyprianouChr @NeophChr @LSE_Angela @Migeotte @drrshamilton for beautiful work
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    Magdalena Zernicka-Goetz
    @ZernickaGoetz
    Feb 17, 2020
    1. I am an immigrant who came from communist-era Poland to the UK and then the US in a search of a more open, unfettered life. In Warsaw, even though my first home was a laboratory, I would have never dreamed that one day I would become a professor at Cambridge and Caltech.