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Leonori Lab
243 posts
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Leonori Lab
@LeonoriLab
Group-run account for the Leonori Research Group at RWTH Aachen University. Catalysis. Photoredox. Organic Synthesis.
Aachen, Germany
leonorigroup.com
Joined September 2017
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  • user avatar
    Leonori Lab
    @LeonoriLab
    Feb 2, 2022
    Excited to share that our group is moving to @RWTH . I would like to thank all my former colleagues for 7 great years at @UoMChemistry and I now look forward to working with new ones!
  • user avatar
    Leonori Lab
    @LeonoriLab
    Aug 5, 2020
    Our work on aniline synthesis from cyclohexanones has been published in @nature today. I wanted to congratulate @DigheShashi, @FabioJulia7 @AlbertoLuridia1 for their work. Great collaboration with James @AstraZeneca! nature.com/articles/s4158…
  • user avatar
    Leonori Lab
    @LeonoriLab
    Sep 15, 2022
    Excited to share our latest work on halogen-atom transfer out today in @ScienceMagazine. We wanted to use a H• to abstract an halogen and identified a process that is under quantum tunnelling control.
    science.org
    Halogen-atom and group transfer reactivity enabled by hydrogen tunneling
    Cyclohexadiene derivatives deliver hydrogen atom equivalents through a tunneling mechanism.
  • user avatar
    Leonori Lab
    @LeonoriLab
    Jan 25, 2024
    Happy to share our latest work on photexcited nitroarenes just published in @NatureChemistry. Check out how we turn them into complex azepanes in just two steps. nature.com/articles/s4155…
    25K
  • user avatar
    Leonori Lab
    @LeonoriLab
    May 20, 2021
    Our new C–H borylation of azines has just been published in @Nature. We use boryl radicals and achieve orthogonal selectivity to the one of Ir/Rh-based approaches!
    Content cover image
    A radical approach for the selective C–H borylation of azines
    From nature.com
  • user avatar
    Leonori Lab
    @LeonoriLab
    Aug 23, 2022
    Happy to share the final version of our work on nitroarenes as ozone surrogates just published in Nature. 1/3 nature.com/articles/s4158…
  • user avatar
    Leonori Lab
    @LeonoriLab
    Apr 23, 2024
    Take a look at our latest work just published in @NatureCatalysis . We have developed a general platform for the desaturative synthesis of aminated heteroaromatics. nature.com/articles/s4192…
    13K
  • user avatar
    Leonori Lab
    @LeonoriLab
    Aug 1, 2022
    Happy to share our latest review on polar effects in radical reactions just published in @NatureSynthesis. We hope you find it useful! nature.com/articles/s4416…
  • user avatar
    Leonori Lab
    @LeonoriLab
    Aug 2, 2024
    Our latest publication in @J_A_C_S demonstrates the use of amine-ligated boryl radical as XAT reagent in alkylation of amides using Cu-catalysis under oxidative conditions, circumventing the low nucleophilicity of amides @RWTH
    A Radical Strategy for the Alkylation of Amides with Alkyl Halides by Merging Boryl Radical-Media...
    From pubs.acs.org
    10K
  • user avatar
    Leonori Lab
    @LeonoriLab
    Nov 13, 2024
    Excited to share our latest work on chemical permutation, now published in @Nature! Using photochemical conditions, we've developed a method to selectively and predictably transform the structures of thiazoles, isothiazoles, and other azole systems.
    23K
  • user avatar
    Leonori Lab
    @LeonoriLab
    Apr 23, 2019
    Our new protocol for the C–H amination of arenes with alkyl amines has been published in @NatureChemistry ! nature.com/articles/s4155… #latestageamination #realtimechem
  • user avatar
    Leonori Lab
    @LeonoriLab
    Jul 15, 2024
    Find our latest publication in @NatureSynthesis on XAT mediated alkylation of both aryl halides and aryl boronic acids. Photogenerated amine-ligated boryl radical can be an effective XAT reagent in nickel and copper catalysed X-coupling reactions!
    Content cover image
    Boryl radical-mediated halogen-atom transfer enables arylation of alkyl halides with electrophilic...
    From nature.com
    8.8K
  • user avatar
    Leonori Lab
    @LeonoriLab
    Aug 14, 2024
    Check out our most recent work in @J_A_C_S. Carboxylated amine-borane serves are boryl radical precursor in radical borylation of styrenes and imines to form novel sp3-organoboron materials directly applicable in Suzuki-Miyaura cross-coupling.
    Synthesis and Suzuki–Miyaura Cross-Coupling of Alkyl Amine-Boranes. A Boryl Radical-Enabled Strategy
    From pubs.acs.org
    12K
  • user avatar
    Leonori Lab
    @LeonoriLab
    Mar 28, 2023
    Our most recent work published in @ACSCatalysis presents a common strategy for the formation of C-C, C-N AND C-O bonds by merging aryl-radical mediated XAT🔦 with Cu-catalysis🔃. Check it out at:
    The Merger of Aryl Radical-Mediated Halogen-Atom Transfer (XAT) and Copper Catalysis for the...
    From pubs.acs.org
    15K

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