Jonas Koeppel

@JonasKoeppel

EMBO postdoctoral fellow | Shendure & Pinglay labs @UW Trying to understand and engineer our wonderfully weird genomes 🧬

Joined June 2020

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Jonas Koeppel
@JonasKoeppel
Jan 31, 2025
I’m delighted to share our work on scrambling the human genome using prime editing, repetitive elements, and recombinases @ScienceMagazine! @ferreira_raph_ @LeopoldParts @ProfTomEllis, @geochurch @sangerinstitute science.org/doi/10.1126/sc… Lots of changes from the preprint. A🧵
Jonas Koeppel
@JonasKoeppel
Jun 3
1/n What fraction of the human genome is essential for cellular viability? Excited to share our preprint that explores this question by combining an unusual CRISPR system, phage promoters, and thousands of deletion launchpads. @sudpinglay @JShendure biorxiv.org/content/10.648…
Jonas Koeppel
@JonasKoeppel
Aug 29, 2025
Highly recommend! Genome wizardry and T cells in one package :D
Raphael Ferreira
@ferreira_raph_
Aug 29, 2025
I’m hiring a PhD student! Come work on #CRISPR + Cancer + T cells 🧬 and help push the boundaries of next-gen immunotherapy. Join us in Copenhagen 🇩🇰 at @DTU_HealthTech !!! Deadline: 30 Sept 2025 efzu.fa.em2.oraclecloud.com/hcmUI/Candidat…
Jonas Koeppel
@JonasKoeppel
Mar 11, 2025
Mikolaj is one of the most amazing scientist and caring person I’ve ever had the pleasure to work with. Not only did he teach me so much on how to do good science, he also showed me how incredibly fun it could be. Highly recommend checking out his lab!
Mikołaj Słabicki
@biomiko
Mar 10, 2025
I am excited to announce the launch of the Slabicki Lab at the Krantz Family Center for Cancer Research within the Mass General Cancer Center and the Cancer Program at the Broad Institute of MIT and Harvard! 🔗 Learn more: slabicki-lab.org
Jonas Koeppel
@JonasKoeppel
Jan 15, 2025
We are happy to share our enhancer scramble story, a strategy to create hundreds of stochastic deletions, inversions, and duplications within mammalian gene regulatory regions and associate these new architectures with gene expression levels 🧵 @LeopoldParts, Pierre Murat