Our new approach to α-amino radical generation using iminium ions and silyl-radicals is now out in @J_A_C_S!
Congratulations Harry for this great study! 🎉
Read it here⬇️
pubs.acs.org/doi/10.1021/ja…
The Gaunt Group
234 posts
The Gaunt Group
@Gaunt_Group
Synthesis. Catalysis. Biology. Technology. Research group @ChemCambridge, @Cambridge_Uni. Student-run account. Formal enquiries should be directed to MJG.
- Our multicomponent strategy for the synthesis of α-Amino Carbonyls is now out in @J_A_C_S! Congratulations to Jianzhong for this great study 🎉 Read the manuscript here⬇️ pubs.acs.org/doi/10.1021/ja…
- The latest work in our carbonyl alkylative amination (CAA) programme is now out in JACS! A big team effort on this one, including some nice high-throughput synthesis. Congrats to Joe, @jrobinsonchem, @TheKumarLab1, John, Nils and @SarahBe07504108!
- Now out in @J_A_C_S, we disclose a Pd-catalysed enantioselective arylation of aminomethyl-cyclopropanes and cyclobutanes, with the tertiary alkylamine motif playing a key role. Great work Jesus, Luke and Javi!
- Our work on the dual-catalytic anion-gated aryl-chlorination of alkenes is now out in @angew_chem. Congratulations Bo, Ala (@ala_bunescu), Daniel, Katherine and Jean. 🎊 Read the paper here ⬇️ onlinelibrary.wiley.com/doi/full/10.10…
- Our Carbonyl Azinylative amination (CAzA) for the synthesis of α-heteroaryl amines is now out in @angew_chem! Congrats Alex (@alex_rafaniello), Roopender (@TheKumarLab1) and Rachel!🎉 Read it here 👇 onlinelibrary.wiley.com/doi/10.1002/an…
- Now out in @J_A_C_S, we show that thiols promote α-amino radical formation from iminium ions under visible light irradiation 💡 via ion-pair charge-transfer complexes! Congrats to @keishi92, Aaron and @miloasmith 🎉 👇
- Our latest report on the synthesis of N-heterospirocycles is out in @J_A_C_S. Well done to Nils, Aaron, Darren, Scarlett and Yongjoon! pubs.acs.org/doi/10.1021/ja… @ChemCambridge
- Out now in @Nature, we show that valuable arylethylamines can be rapidly assembled by the cooperative action of two distinct Cu catalysts, with the azide anion playing a key role in turnover. Congrats to Ala and Yusra 🎉 check out their hard work below👇 nature.com/articles/s4158…
- Now out in @J_A_C_S, we disclose the latest advance in our photocatalytic hydroaminoalkylation methodology: a highly modular alpha-tertiary amine synthesis via imine redox-relay.💡Congrats to @jhenryb62, @GeorgiaRitzema and @miloasmith 🎉
- Congrats to @GeorgiaRitzema (with a helping hand from @TrowbridgeGroup) for publication of her work on photocatalytic asymmetric alpha-tertiary amine synthesis in @JOC_OL! 😻🎉 A really neat method for stereocontrol at a-amino radicals. Check it out!
- 🚨Open PhD position Alert 🚨 come to join our team and work on some exciting chemistry!Come and join our team. We have an exciting Synthetic Chemistry PhD opportunity in the @Gaunt_Group (starting Oct 2025) in collaboration with AstraZeneca. It will focus development of new catalytic activation modes for the synthesis of novel scaffolds. jobs.cam.ac.uk/job/48481/
- Our work on selective reactions at methionine residues as a protein functionalization platform is now out in @nature! Congrats to Mike, Jen and Marcos, thanks for your hard work! @ChemCambridge disq.us/t/37azdeo
- Our multicomponent method for a-branched secondary alkylamine synthesis via carbonyl alkylative amination is now out in @ChemicalScience! 🎊 Congrats @miloasmith, @RJDKang, @TheKumarLab1 and Biswarup! 🥳 Read it here 👇 pubs.rsc.org/en/content/art…
