Elliot Hershberg (@ElliotHershberg) / X

Elliot Hershberg

3,364 posts

Elliot Hershberg

@ElliotHershberg

Partner @AmplifyPartners, writing centuryofbio.com

San Francisco, CA

Joined October 2011

Pinned
Elliot Hershberg
@ElliotHershberg
Jun 5, 2025
Announcing Amplify Bio 🧬 I've joined Amplify Partners to help build a $200M fund dedicated to technical founders in bio. This has been part of a long evolution—from writing code as a computational biologist, to writing >200k words about this sector in The Century of Biology,
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Elliot Hershberg
@ElliotHershberg
May 2, 2024
Humans: nanotechnology will never work!!! Bacteria: hold my beer.
Prash Singh
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Prash Singh
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Elliot Hershberg
@ElliotHershberg
Jun 27, 2024
Protein design for ...checks notes... growing semiconductors (!!) Biology is nanotechnology.
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Elliot Hershberg
@ElliotHershberg
Oct 9, 2025
Crazy example of Chinese biotech cycle times: I'm reading a new bioRxiv preprint from a Chinese research team about a new circular RNA modality. It's about a cool idea to embed aptamers into circular RNAs. The circularity confers stability and the aptamers confer targeting. So
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Elliot Hershberg
@ElliotHershberg
Mar 1, 2025
Extremely clever new NGS tech from Roche 🧬 If it's hard to discriminate between nucleic acids accurately with a nanopore, why not synthesize a new polymer off a DNA template that is easier to sequence? It's an intuitively simple idea, but took *a ton* of creative nucleic acid
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Elliot Hershberg
@ElliotHershberg
Feb 18, 2024
In the past few weeks, there's been an explosion of new tools for programming DNA and RNA 🧬 A thread with everything you need to know about these new results:
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Elliot Hershberg
@ElliotHershberg
Aug 31, 2024
Three of my favorite papers published this week: 1. A mechanism for bacteria to create *new* repetitive toxic genes to kill themselves in response to infection (!!)
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Elliot Hershberg
@ElliotHershberg
Nov 16, 2025
Our first labor of love is complete. My wife painted every stripe in the nursery by hand. We are excited to welcome our daughter into the world in the New Year!
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Elliot Hershberg
@ElliotHershberg
Jan 30, 2022
I've spent several years building software tools in genomics. While the work couldn't be more exciting, there are unique challenges and tensions in the world of scientific software. How does software in the life sciences actually work (and not work)?
How Software in the Life Sciences Actually Works (And Doesn’t Work) - …
From newscience.org
Elliot Hershberg
@ElliotHershberg
Dec 23, 2022
It's dizzying keep up with BioML 🧬 Not one, not two, but THREE exciting papers from the @MetaAI Protein Team before the end of the year. Here's what they released:
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Elliot Hershberg
@ElliotHershberg
Feb 25, 2025
Gene therapy restores hearing (!!) This is the goal. Beautiful mechanistic therapies with effect sizes so big that they can be seen in the very first dozen patients dosed. Congrats to the one and only Steve Holtzman and the Decibel team for establishing this program, and to
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Elliot Hershberg
@ElliotHershberg
Nov 7, 2022
We are currently pursuing the industrialization of biotech 🏭 In a new essay, I explore the following question: What if we pursue the biologization of industry? 🧬
Elliot Hershberg
@ElliotHershberg
Oct 5, 2022
In the future, medicines will be programmable 🧬 An exciting day for RADAR technology:
Elliot Hershberg
@ElliotHershberg
May 26, 2023
AlphaFold wouldn't have been possible without the PDB. What will be the equivalent be for structure-based *drug discovery*? Very cool new resource called MISATO: nearly 20,000 experimental structures of protein-ligand complexes + associated properties:
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