File photograph of Mass General Brigham's corporate office in Somerville Mass.
Mass General Brigham’s corporate office in Somerville, Mass.David L. Ryan/The Boston Globe

This story originally appeared in STAT’s sister publication, The Boston Globe.

Mass General Brigham said Monday it will let go of hundreds of employees in the next two months, the largest layoff in the organization’s history, as the health system grapples with anticipated financial shortfalls and ongoing operational challenges at its 12 hospitals.

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With roughly 82,000 employees, MGB is easily the state’s largest private employer. Executives declined to say how many people would be let go, but said the target is to save at least $200 million annually, or approximately 2% of its salary and benefits costs. The cuts, which will occur this week and then again in a second round in March, would likely have rolled out more slowly over the course of years as the health system more closely integrates its hospitals, executives said, but have been sped up because of financial pressures.

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