Enabling Precision Data for Precision Medicine
Sentieon® develops and supplies accelerated bioinformatics secondary analysis tools that process genomics data with high computing efficiency and exceptional accuracy.
Award Winning Products


- Microsoft Healthcare Blog - $0.33 whole genome analysis on Azure spot instances
- AMD White Paper -12x cheaper and faster long reads analysis with 4th Gen AMD EPYC
- ARM HPC Blog - fully support AWS Graviton and other ARM CPUs
- Intel Health Analytics Case Study - ONT long reads single cell rapid analysis
- Dell Technologies Whitepaper - Direct comparison with Parabricks on short and long reads
What We Offer
Sentieon® Sequencer Agnostic Secondary Analysis - FASTQ-BAM-VCF-GVCF
CPU/ARM accelerated software for drop-in replacements/improvements for BWA-MEM, STAR, Minimap2, GATK, Mutect2, and large cohort joint calling. DNAscope pipeline supports both short reads and long reads from all mainstream sequencing platforms.
- Uncompromising accuracy
- Fast turnaround: <30 min on 30x WGS
- Cost efficient
- Support for all short and long read sequencers
The Sentieon® tools achieve their efficiency and consistency through optimized computing algorithm design and enterprise-strength software implementation, and achieve high accuracy using the industry’s most validated mathematics models.
Sentieon® solutions are easily scalable, easily deployable, easily upgradable, software-only solutions.
Our Tools In Use
Sentieon software runs on any Intel, AMD, or ARM server.
Accumulated Core Hours
1,007,761,389+
Trusted By Clients
1,860+
Total Data Processed
4,976,999+
Quotes From Customers
“Sentieon is the best. Frankly the best support team I have encountered - they are clearly experts” - University of Michigan
“Not only are we pretty happy, Sentieon is hands down without comparison the best vendor we work with, bar none” - Mayo Clinic
“Since using Sentieon, we’ve seen time savings, less frustration, and the ability to process a large number of samples” - Iowa State University
“Since using Sentieon, I have peace of mind, and am assured that innovation is coming our way” - M42
“Sentieon provides better runtimes, lower compute cost, and consistency. We had the ambitious goal of generating genotype data for 150 animals that had no previous genomic data - Sentieon was a contributor to that success” - California Conservation Project