ANTIBIOTIC RESISTANCE
INTRODUCTIO
N
Antibiotic resistance occurs when
bacteria develop mechanisms to
evade the effects of antibiotics,
making them ineffective against
infections. This can lead to
increased morbidity, mortality,
and healthcare costs.
CURRENT DATA
/STATISTICS AFRICA
AND NIGERIA ARE
APPLICABLE
• Antibiotic resistance is a
growing concern globally,
including in Africa and
Nigeria. The misuse and
overuse of antibiotics have
accelerated the
development of resistant
bacteria, making infections
harder to treat ¹
• SCIENTIFIC EXPLANATION
• - Genetic mutations: Bacteria can develop genetic mutations that
confer resistance to antibiotics.
• - Horizontal gene transfer: Bacteria can share resistant genes
with each other.
• - Overuse and misuse of antibiotics*: Inappropriate prescribing
and use of antibiotics accelerate the development of resistance.
• PHARMACEUTICAL IMPLICATIONS
• - Increased morbidity and mortality: Resistant infections can lead
to prolonged illnesses and increased risk of death.
• - Limited treatment options: Resistance can limit the
effectiveness of available treatments, making it challenging to
manage infections.
SCIENTIFIC • - Need for new antibiotics: Developing new antibiotics with novel
EXPLANATION ,PH mechanisms of action is crucial to combat resistance.
ARMACEUTICAL • CASE STUDIES
IMPLICATIONS OR • - Nigeria's antibiotic resistance crisis: Studies have shown that
antibiotic resistance is a significant public health concern in
CASE STUDIES Nigeria, with high resistance rates to commonly used antibiotics .
PUBLIC
HEALTH
• Antibiotic resistance is a
significant public health
concern that requires a
multifaceted approach to
prevention and control.
Promoting responsible
antibiotic use, improving
infection control practices,
and investing in research
and development are
essential to mitigating the
impact of antibiotic
resistance on public health.
SOLUTION
• 1. Practice good hygiene:
Wash hands regularly,
especially when interacting
with healthcare systems.
• 2. Use antibiotics responsibly:
Only use antibiotics as
prescribed by a healthcare
professional and complete
the full course of treatment.
• 3. Get vaccinated: Stay up-
to-date on recommended
vaccinations to prevent
infections.
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increasing
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REFERENCES •
05-05.
"CDC Press Releases". CDC. January 2016. Retrieved 2016-05-05.
