DIPHYLLOBOTHRIUM
LATUM
THE LIFE CYCLE OF FISH TAPEWORM
- BY CHELSI BALLARI
- ROLL NUMBER 13
INTRODUCTION
• Diphyllobothrium latum is also called as fish tapeworm or dog
tapeworm.
• It belongs to the class of cestodes, in family of Diphyllobothridae.
• It is endemic to Europe, Siberia, Japan and India
MORPHOLOGY
• It is the longest tapeworm found in man found upto a length of 10
meters or more.
• It contains as many as 3000 or more proglottids
• It is found in small intestine in ileum
• It consists of scolex, neck and strobila.
ADULT WORM OF DIPHYLLOBOTHRIUM
LATUM
• Scolex :
• The head is called as scolex
• It is spoon shaped and 2-3mm in length and 1mm in breadth
• It has 2 slit like groves
• No rostellum and hooklets
• Neck :
• It is behind scolex
• It is unsegmented and long
• Strobila :
• It has 3000 or more proglottids.
• It has immature, mature and gravid proglottids in that order.
• Mature proglottid has male and female reproductive organs
• Terminal segment discharges upto one million eggs daily.
• They are broken off and released.
EGG
• Egg is yellow colour ( bile stained)
• It is oval shaped
• It has operculum on one end and a knob on other end
• It has immature embryo
• It is not infective to humans
OPERCULATED EGG
LARVAL STAGES
• It has 3 stages of larvae.
• The first stage larvae is in water, known as coracidium.
• The second stage larva is in fresh water copeped cyclops (first
intermediate host) called as procercoid.
• The third stage is in fresh water fish called as plerocercoid.
LIFE CYCLE
• Definitive host :
• Man is main definitive host.
• Sometimes dogs, cats, pigs, foxes and bears
• Intermediate host :
• First intermediate host : copepods of genera Dioptomus and Cyclops
• Second intermediate host : Freshwater fishes
• Adult worm resides in small intestine of man
• Its operculated eggs are passed in feces.
• The embryo with 3 pairs of hooks
• It matures in 1-2 weeks and emerges through operculum as
coracidium.
• It is ingested by freshwater copepod.
• It penetrated the intestine and enters the body cavity.
• It transforms into procercoid larva.
• The infected copepod is ingested by freshwater fish.
• It penetrates intestine and enters muscle fibers of the fish
• It transforms into plerocercoid larva and measures 10-20mm x 2-
3mm.
• It is infective stage for man.
• Humans are infected when they consume infected fish
• It develops into adult worm and starts laying eggs in about 5-6 weeks.
• The eggs are released though feaces and continues the cycle.
LIFECYCLE OF DIPHYLLOBOTHRIUM LATUM
LIFE CYCLE OF DIPHYLLOBOTHRIUM LATUM
PATHOGENESIS
• Most infections cause no effect
• Patient develops fatigue, weakness, diarrhea, numbness of lips etc.
• It sometimes develops vitamin B12 deficiency.
LABORATORY DIAGNOSIS
• Stool microscopy is the investigation done
• It is diagnosed by identifying operculated eggs in feaces.
• The proglottids passed in feaces are identified
TREATMENT
• Praziquantel is drug of choice.
• Alternate drug in niclosamide.
• Tab. Vitamin B12 is taken to correct deficiency
PROPHYLAXIS
• Proper cooking of fish
• Prevention of fecal pollution of natural water
• Proper sanitation and disposal of feaces
• Antimicrobial therapy of infected humans
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