Increased Intracranial Pressure
Monro-Kellie hypothesis: because of limited
space in the skull, an increase in any one skull
component—brain tissue, blood, or CSF—
necessitates a change in the volume of
another
Compensation to maintain a normal ICP of 10 to
20 mm Hg is normally accomplished by
shifting or displacing CSF
With disease or injury, ICP may increase
Increased ICP decreases cerebral perfusion,
causes ischemia, cell death, and (further)
edema
ICP and CPP
Normal ICP is 10 to 20 mmHg
CCP (cerebral perfusion pressure) is closely linked
to ICP
CCP = MAP (mean arterial pressure) – ICP
Normal CCP is 70 to 100
A CCP of less than 50 results in permanent
neuralgic damage
Early Signs of ICP
The earliest sign of increasing
ICP is a change in LOC.
Slowing of speech and delay in
response to verbal suggestions
are other early indicators.
Detecting Early Indications of Increasing ICP
Disorientation, restlessness, increasing agitation,
increased respiratory effort (Kussmaul breathing),
purposeless movements, and mental confusion.
Pupillary changes and impaired extraocular
movements.
Weakness in one extremity or on one side of the
body.
Headache that is constant, increasing in intensity,
and aggravated by movement or straining.
Other manifestations include:
Behavior changes
Seizures
Nausea and Vomiting
Lethargy
in ICP is a medical
emergency
Treatment should be
initiated immediately
Ways to relieve an increase in ICP
Decrease Cerebral Edema Maintaining Cerebral
Mannitol Perfusion
Fluid Restrictions Dobutrex
Assess BP, skin turgor, Levophed
mucous membranes,
urine output & osmolality Keep head in a midline
IV Fluids prescribed – position
slow to moderate rate Avoid extreme hip
Oral hygiene b/c of flexion
dehydration
Avoid the Valsalva
maneuver
Ways to relieve an increase in ICP
Controlling Fever
Antipyretic medications
Reducing CSF and Hypothermia blanket
Intracranial Blood Avoid shivering in the patient
Volume Removing all bedding over the
Drain CSF patient (except for a light sheet)
Giving cool sponge baths and
Aseptic technique an electric fan to facilitate
and assess for signs cooling
of infection Monitor temperature
frequently – monitor response
Hyperventilation – as to therapy and to prevent
a last resort excess decrease in temperature
and shivering
Ways to relieve an increase in ICP
Maintaining Reducing Metabolic
Oxygenation Demands
Maintain a patent airway High doses of
Discourage coughing and barbiturates
straining Paralytics
Auscultate lungs every 8
hours
Monitor ABGs and Pulse
oxymetry
Optimize hemoglobin
saturation
Due to the use of paralyzing agents patient
will require:
Continuous cardiac monitoring
Endotracheal intubation
Mechanical ventilation
ICP monitoring
Arterial pressure monitoring
Monitoring ICP
Ventriculostomy:
AKA Ventricular Catheter Monitoring Device
Fine bore catheter is inserted into the non-dominant
hemisphere of the brain
Catheter connected to a transducer that monitors the
ICP and Records data-Oscillator scope
Allows for ICP relief by allowing for CSF release thus
relieving intercranial HTN
Intraventricular Med Administration access
Air or contrast administration for Ventriculography
Complication of
Ventriculostomy:
Infection
Meningitis
Ventricular
Collapse
Occlusion of
catheter device by
brain or blood
materials
Problems with Ventriculostomy with fiber optic transducer-
tipped device
monitoring system
Monitoring ICP (continued)
Subarachnoid Screw or Bolt:
Screw or bolt is a hollow screw that is inserted
through a hole drilled in the skull and through a
hole cut in the dura mater in to the subarachnoid
space.
Hollow screw avoids complications from brain shifting
Doesn’t require ventricular puncture
Infection & clogging screw with brain matter affecting
readings
Subarachnoid screw or bolt
Monitoring ICP (continued)
Epidural Sensor:
Epidural Device is placed through a burr hole
drilled in the skull, just over the epidural
covering. Uses pneumatic pressure to signal
an alarm for pressure abnormalities.
Epidural lining is not perforated, thus less invasive
& less infection
Cannot relieve excess CSF.
Monitoring ICP (continued)
Fiber Optic Sensor
Fiber Optic device can be inserted into the
ventricle, subarachnoid and subdural space.
Mini-Transducer converts ICP readings into
electronic digital monitoring
When inserted in to the ventricle can allow for
CSF withdrawal.
Trending ICP Values
ICP Waves:
A Waves-Can last 5-20
minutes with amplitudes
between 50-100 mmHg
B Waves-30 seconds to 2
minutes with amplitudes
up to 50 mmHg
C Waves – Occur up 6
times a minute with
amplitudes up to 25
mmHg
New Trends in Neuro Monitoring
Licox Catheter
A 3 in 1 white matter catheter
that measures ICP,
Temperature, and end
capillary tissue oxygen level.
Gives real time feed back of
ICP management, guiding
therapy and oxygenation of
tissue at risk in the cerebrum.
The temperature probe can
be replaced with a
microdialysis probe
Picture from INTREGA website: http://www.integra-is.com/PDFs/licox/NS327%20ICP%20Catheter%20w%20IMC%20Bolt.pdf.
Late Manifestations of Increased ICP
Further deterioration of LOC; stupor to coma
Decreasing level of responsiveness &
consciousness
Reacting only to loud or painful stimuli
Deterioration of motor function; abnormal
motor responses
Hemiplegia, decortications, decerebration, or
flaccidity may occur (abnormal posturing)
Decorticate Posturing
Decerebrate Posturing
Late Manifestations of Increased ICP cont.
Alterations in vital signs
Increase in systolic blood pressure
Widening of pulse pressure
Slowing of the heart rate; pulse may fluctuate rapidly
from tachycardia to bradycardia
Increase in temperature
Cushing’s Triad: bradycardia, hypertension, &
bradypnea
Immediate intervention required to prevent herniation of
brain stem & occlusion of blood flow
Cessation of cerebral blood flow results in cerebral
ischemia, infarction, & brain death
Late Manifestations of Increased ICP cont.
Visual changes; pupillary changes reflecting pressure on
optic/oculomotor nerves
Pupils decrease or increase in size or become unequal
Lack of conjugate eye movement
Papilledema
Projectile vomiting may occur with increased pressure
on the reflex center in the medulla
Loss of brain stem reflexes, including pupillary, corneal,
gag, & swallowing reflexes
Loss of reflexes is an ominous sign of approaching brain
death
Late Manifestations of Increased ICP cont.
Classic fixed and
dilated “blown
pupil”
Absence of
oculocephalic
reflex or “doll’s
eye”
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Late Manifestations of Increased ICP cont.
Major complication of
Increased ICP - Hernation
(1) Herniation of the
cingulate gyrus under the
falx cerebri. (2) Central
transtentorial herniation. (3)
Uncal herniation of the
temporal lobe into the
tentorial notch. (4)
Infratentorial herniation of
the cerebral tonsils.
Late Manifestations of Increased ICP cont.
Diabetes insipidus is the result
of decreased secretion of
antidiuretic hormone (ADH).
SIADH is the result of
increased secretion of ADH.
All information other than the Licox slide, and ‘blown pupil’ slide is from Brunner & Suddarth’s Textbook of Medical-Surgical Nursing, 11 th edition
http://thepointeedition.lww.com/pt/re/9780781759786/bookcontent.01269236-11th_Edition-4.htm;jsessionid=JDwGTQLQgQ7mx2GyvpyknRhhvPRV
J2Z6KpkpX2sJTT983RtPFhyL!-985563194!181195629!8091!-1 Information compiled by Stephen Strom, Michelle Harris, Angela Reaves, Suzanne Finch, and
Amanda King
