15
PART B
The Urinary System
PowerPoint® Lecture Slide Presentation by Jerry L. Cook, Sam Houston University
ESSENTIALS
OF HUMAN
ANATOMY
& PHYSIOLOGY
EIGHTH EDITION
ELAINE N. MARIEB
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Urinary Bladder
Smooth, collapsible, muscular sac
Temporarily stores urine
Figure 15.6
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Urinary Bladder
Trigone – three openings
Two from the ureters
One to the urethrea
Figure 15.6
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Urinary Bladder Wall
Three layers of smooth muscle (detrusor
muscle)
Mucosa made of transitional epithelium
Walls are thick and folded in an empty
bladder
Bladder can expand significantly without
increasing internal pressure
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Urethra
Thin-walled tube that carries urine from the
bladder to the outside of the body by
peristalsis
Release of urine is controlled by two
sphincters
Internal urethral sphincter (involuntary)
External urethral sphincter (voluntary)
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Urethra Gender Differences
Length
Females – 3–4 cm (1 inch)
Males – 20 cm (8 inches)
Location
Females – along wall of the vagina
Males – through the prostate and penis
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Urethra Gender Differences
Function
Females – only carries urine
Males – carries urine and is a passageway
for sperm cells
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Micturition (Voiding)
Both sphincter muscles must open to allow
voiding
The internal urethral sphincter is
relaxed after stretching of the bladder
Activation is from an impulse sent to the
spinal cord and then back via the pelvic
splanchnic nerves
The external urethral sphincter must be
voluntarily relaxed
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Micturition Reflex= 200- 300mL
Urination proper= 500-800 mL
“DRIBBLES” = 801 mL
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Maintaining Water Balance
Normal amount of water in the human body
Young adult females – 50%
Young adult males – 60%
Babies – 75%
Old age – 45%
Water is necessary for many body functions
and levels must be maintained
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Distribution of Body Fluid
Intracellular fluid
(inside cells)
Extracellular fluid
(outside cells)
Interstitial fluid
Blood plasma
Figure 15.8
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The Link Between Water and Salt
Changes in electrolyte balance causes water
to move from one compartment to another
Alters blood volume and blood pressure
Can impair the activity of cells
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Maintaining Water Balance
WATER INTAKE = WATER OUTPUT
Sources for water intake
Ingested foods and fluids
Water produced from metabolic processes
Sources for water output
Vaporization out of the lungs
Lost in perspiration
Leaves the body in the feces
Urine production
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Maintaining Water Balance
Dilute urine is produced if water intake is
excessive
Less urine (concentrated) is produced if
large amounts of water are lost
Proper concentrations of various electrolytes
must be present
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Regulation of Water and Electrolyte
Reabsorption
Regulation is primarily by hormones
Antidiuretic hormone (ADH) prevents
excessive water loss in urine
Aldosterone regulates sodium ion content
of extracellular fluid
Triggered by the rennin-angiotensin
mechanism
Cells in the kidneys and hypothalamus are
active monitors
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Maintaining Water and Electrolyte
Balance
Figure 15.10
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Maintaining Acid-Base Balance in Blood
Blood pH must remain between 7.35 and
7.45 to maintain homeostasis
Alkalosis – pH above 7.45
Acidosis – pH below 7.35
Most ions originate as byproducts of cellular
metabolism
KIDNEYS AND LUNGS work to maintain
the acid-base balance
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Dec Ph level= ACIDIC
Inc Ph level= ALKALOSIS
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ACID-BASE BALANCE
Ph 7.35-7.45
HCO3: 35-45
PACO2: 22-26
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Maintaining Acid-Base Balance in Blood
Most acid-base balance is maintained by the
kidneys
Other acid-base controlling systems
Blood buffers
Respiration
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Blood Buffers
Molecules react to prevent dramatic changes
in hydrogen ion (H+) concentrations
Bind to H+ when pH drops
Release H+ when pH rises
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The Bicarbonate Buffer System
Mixture of carbonic acid (H2CO3) and
sodium bicarbonate (NaHCO3)
Bicarbonate ions (HCO3–) react with strong
acids to change them to weak acids
Carbonic acid dissociates in the presence of
a strong base to form a weak base and
water
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The Bicarbonate Buffer System
Needs good renal function (HCO3-
regulation)
Converts H+ (hydrogen) to H2CO3
(carbonic acid) which is then able to be
“blown off” via the lungs as CO2.
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Respiratory System Controls of Acid-
Base Balance
Carbon dioxide in the blood is converted to
bicarbonate ion and transported in the plasma
Increases in hydrogen ion concentration
produces more carbonic acid
Excess hydrogen ion can be blown off with
the release of carbon dioxide from the lungs
Respiratory rate can rise and fall depending
on changing blood pH
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Respiratory System Controls of Acid-
Base Balance
CO2 diffuses passively into the cerebrospinal
fluid and the medulla controls rate and depth
of respiration
Dependent on HCO3- stores and adequate gas
exchange
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Renal Mechanisms of Acid-Base Balance
Excrete bicarbonate ions if needed
Conserve or generate new bicarbonate ions if
needed
Urine pH varies from 4.5 to 8.0
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Developmental Aspects of the Urinary
System
Functional kidneys are developed by the third
month
Urinary system of a newborn
Bladder is small
Urine cannot be concentrated
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Developmental Aspects of the Urinary
System
Control of the voluntary urethral sphincter
does not start until age 18 months
Urinary infections are the only common
problems before old age
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Aging and the Urinary System
There is a progressive decline in urinary
function
The bladder shrinks with aging
Urinary retention is common in males
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