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Understanding Poison Toxicity Mechanisms

The document discusses various topics related to toxicology and poisoning including: 1) The importance of understanding the toxic mechanism of a poison is to know what vital functions will be affected, the potential severity of the case, and to help decide the appropriate course of action. 2) Sulfuric acid is a classical example of a poison that can cause both systemic and local effects. 3) Absorption of the poison refers to the poison reaching systemic circulation from the site of exposure. 4) The most important factor regarding the expected severity of a poisoning case is the dose of the poison administered.

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750 views15 pages

Understanding Poison Toxicity Mechanisms

The document discusses various topics related to toxicology and poisoning including: 1) The importance of understanding the toxic mechanism of a poison is to know what vital functions will be affected, the potential severity of the case, and to help decide the appropriate course of action. 2) Sulfuric acid is a classical example of a poison that can cause both systemic and local effects. 3) Absorption of the poison refers to the poison reaching systemic circulation from the site of exposure. 4) The most important factor regarding the expected severity of a poisoning case is the dose of the poison administered.

Uploaded by

esraa
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PPTX, PDF, TXT or read online on Scribd
  • Toxic Mechanisms of Poisons
  • Systemic and Local Effects of Poisons
  • Types of Hypoxia
  • Direct Toxic Mechanisms
  • Indicators of Poisoning
  • Factors Influencing Poisoning Severity
  • Importance of Understanding Toxic Mechanisms
  • Sources of Poisons and Their Severity
  • Management of Inhaled Poisons
  • Examples of Direct Toxic Mechanisms
  • Absorption Routes of Poisons
  • Understanding Poison Absorption
  • Identifying Poisons by Smell
  • Corrosive Acids with Dual Action
  • Misconceptions in Toxicology

Why is it important to know the toxic mechanism of a poison?

a) To know what vital function will be


affected.
b) To know the potential severity of the
case.
c) It helps to decide what course of
action will be taken.
d) All of the above.
A classical example of a poison that can give both systemic and local effects is:

a) Oxalic acid.
b) Sulfuric acid.
c) Alkali
d) All of the above.
Types of hypoxia include
a) Hypoxic hypoxia
b) Anemic hypoxic
c) Cytotoxic hypoxia
d) Stagnant hypoxia
e) All of the above
Which of the following is a direct toxic mechanism:

a) Binding of the poison to cellular protein.


b) Inhibition of an enzyme.
c) Burning of the skin by a mineral acid.
d) Formation of a toxic metabolites.
Which of the following indicators is most helpful to you in deciding
whether you have a case of poisoning or not?

a) Signs and symptoms.


b) Laboratory analysis.
c) A witness saw the incidence.
d) Presence of the poison with poisoned
person.
In general, which of the following factors is the most important
regarding the expected severity of a case of poisoning?

a) Dose of the poison.


b) Age of the person.
c) Sex of the person.
d) Form of the substance.
e) Route of exposure.
Why is it important to know the toxic
mechanism of a poison?

a) To know what vital function will be affected.


b) To know the potential severity of the case.
c) It helps to decide what course of action will be taken.
d) All of the above.
e) Only A & C.
The source of poison that give least frequent number of cases
but most serious is:

A. Animal source.
B. Plant source.
C. Chemical source.
D. All of the above give almost the same
frequency of cases.
When a poison is inhaled what methods you will be thinking of to
manage the case?

a) Induction of emesis.
b) Carrying out a gastric lavage.
c) Thinking of an active elimination technique.
d) Administration of a suitable antidote.
e) Both (C) & (D) are possible.
The following is a good example of direct toxic mechanism:

a) A burn of student hand in the lab by a sulfuric


acid.
b) Inhibition of AchE in a case of organophosphate
poisoning.
c) Death due to asphyxia by CO poisoning.
d) Interruption of protein synthesis by a heavy
metal.
e) Depletion of liver glutathione by paracetamol
poisoning.
Absorption of the poison is more by:

A) inhalation
B) ingestion
C) Skin contact
D) Absorption is similar in all
routes
Absorption of the poison means

A) Poison reaches circulation


B) Poison leaves blood to tissues
D) Effect of the poison on receptors
E) none of the above
Which of the following poisons can be
identified by smell?

A. parathion.
B. Alcohol.
C. Hashish.
D. All of the above.
E. None of the above.
• Which of the following corrosive acids
can cause both local and systemic
action?

A. Oxalic acid.
B. Hydrochloric acid.
C. Sulfuric acid.
D. All of the above.
Select the wrong statement
a) Toxicology is the science of poisons
b) Forensic toxicology deals with the
identification of legal aspects of
poisoning
c) The poison is the substance that
causes harmful effects to the living
organism
d) All poisons are toxins

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