DI
P
H
By:
T ELGARIO, Mariane
H IBAAN, Shyluck May
E RABOY, Mario Elizer
RI RAPACON, Jobelle
A
DEFINITION:
acute contagious disease characterized by
general toxemia emanating from localized
inflammatory process characterized by the
formation of “pseudomembrane” commonly
in the face area & tonsils, & the elaboration
of a powerful exotoxin affecting the impt.
viscera as the heart & kidneys & the
peripheral nervous system.
CAUSATIVE AGENT:
Corynebacterium diphtheriae or Klebs Loffler
bacillus > gram positive rod
RESERVOIR: Man
SOURCE: Discharges or secretions from nasopharynx
MODES OF TRANSMISSION:
Direct contact – discharges form respiratory
passages; saliva
Indirect contact – though various articles including
toys & clothing contaminated by infected
individual
INCUBATION PERIOD:
1 to 7 days
PERIOD OF COMMUNICABILITY:
2 to 4 weeks, average: 2 weeks
SIGNS AND SYMPTOMS:
fever,
red sore throat,
weakness,
Headache
difficulty swallowing, or
difficulty breathing
dryness & excoration of upper lip & nares
bull neck appearance
Laryngeal stridor
Hoarseness of voice
“PSEUDOMEMBRANE” > Hallmark sign ( thick gray
covering in the back of throat that can make breathing
difficult)
DIAGNOSTIC EXAM:
Nose & throat culture – there must be 3
consecutive (-) result
Schick’s test – determine susceptibility &
immunity to diphtheria.
Molony test – determine hypersensitivity to
diphtheria anti-toxin
TREATMENT:
Drugs
(ADS) anti-diphtheria serum à to neutralize
toxins = IM, IV ANST
Antibiotics – Penicillin G. Sodium, Eythromycin to
kill the causative agent
Supportive
O2 inhalation
Tracheostomy
Suction secretions
NURSING CARE:
TSB for fever
Provide liquid to soft diet with minimal
CHON & sufficient CHO
Strict isolation
CBR – no early ambulation
Increase fluid intake
Small frequent feedings
Maintain patent airway
Proper disposal of naso-pharyngeal secretions
Diversional activities to children
COMPLICATIONS:
Myocarditis – dec apical pulse < 60 lead to
cardiac arrest.
Peripheral neuritis
Broncho pneumonia
Encephalitis
Cerebral Infarction
Renal Function
Shock
PREVENTION:
Avoid MOT
Immunization – DPT 0.5cc IM – vastus lateralis
given at the same time with OPV 6,10,14 wks
after DPT don’t massage to prevent lump
forming
put hot moist compress if with lump formation
expect fever within 24 hrs -- give Paracetamol
q4hours for 24 hours
check patient's temp before giving DPT
don't give succeeding doses if patient
experienced convulsion