G.I.
Bleeding
dr. Diah Ari Safitri, SpPD
G.I. Bleeding
Acute Vs Chronic
Acute Upper G.I.Bleeding
Acute Lower G.I.Bleeding
Acute Upper G.I. Bleeding
Haematemesis
Melaena
Acute U.G.I. Bleeding
Aetiology
Drugs (Aspirin & NSAIDs)
Alcohol
Chronic peptic ulceration
– (50% of GI hemorrhage)
Others:
– reflux esophagitis,
– varices,
– gastric carcinoma,
– acute gastric ulcers & erosions.
Acute U.G.I. Bleeding
Clinical approach
recent (24 hrs)
if small amount, no immediate Tx,
– CVS can compensate
85% stop bleeding during 48 hrs
history helps in diagnosing the cause
of the hemorrhage,
factors include:
age (60 +)
amount of blood lost
continuing visible blood loss.
signs of chronic liver disease
classical clinical features of shock
Acute U.G.I. Bleeding
Immediate management
Emergency management:
History + exam
Monitor: pulse & BP /30 min
Bld sample: Hb, urea, electrolytes, grouping &
cross-matching
I.v. access
Bld transfusion in case of
– shock
– Hb <10 g/dl
Urgent endoscopy
Surgery when recommended
Shock management: ABC
Airway
endotracheal tube, oropharyngeal airway.
Give oxygen
Breathing
support respiratory function
Monitor: resp. rate, bld gases, chest radiograph
• Circulation
• expand circulating volume: blood, colloids, crystalloids
Monitor: skin color, peripheral temp., urine flow, BP, ECG
Acute U.G.I Bleeding
General Investigations
1. Hb
2. CBC
3. Bld glucose
4. Platelets, coagulation
5. Urea, creatinine, electrolytes
6. Liver biochem.
7. Acid-base state
8. Imaging: chest & abd. radiography,
US, CT
Acute U.G.I. Bleeding
General management:
Blood volume
1. restore volume to normal
2. transfusion
Endoscopy
1. shock, suspected liver disease or
continued bleeding
2. control varices or ulcers to reduce
re-bleeding
Drug therapy
1. H2 – receptor antagonists
2. proton pump inhibitors
Factors in reassessment
1. age: 60 + greater mortality
2. recurrent hemorrhage: +++ mortality
3. re-bleeding: mostly within the 1st 48 hrs
4. surgical procedures in case of severe
bleeding.
Lower gastrointestinal
haemorrhage
Causes
• Angiodysplasia
• Diverticular disease
• Inflammatory bowel disease
• Ischaemic colitis
• Infective colitis
• Colorectal carcinoma
Lower gastrointestinal haemorrhage
Investigation
• Most patients are stable and can be
investigated once bleeding has stopped
• In the actively bleeding patient consider
• Colonoscopy - can be difficult
• Selective mesenteric angiography
• Requires continued bleeding of >1 ml/minute
• May show angiodysplastic lesions even once
bleeding has ceased
•Radionuclide scanning
•Uses technetium-99m labeled red blood cells
Management
• Acute bleeding tends to be self limiting
• Consider selective mesenteric embolisation if life
threatening haemorrhage
• If bleeding persists perform endoscopy to exclude
upper GI cause
• Proceed to laparotomy and consider on-table lavage
an panendoscopy
• If right-sided angiodysplasia perform a right
hemicolectomy
• If bleeding diverticular disease perform a sigmoid
colectomy
• If source of colonic bleeding unclear perform a
subtotal colectomy and end-ileostomy