Effects of Human Growth Hormone
Process Diagrams Step-by-Step
Copyright 2007 by John Wiley & Sons, Inc.
1 Low blood glucose (hypoglycemia) stimulates release of
GHRH
1 Low blood glucose (hypoglycemia) stimulates release of
GHRH
2 GHRH stimulates secretion of hGH by somatotrophs hGH
1 Low blood glucose (hypoglycemia) stimulates release of
GHRH
2 GHRH stimulates secretion of hGH by somatotrophs hGH
3 hGH and IGFs speed up breakdown of liver glycogen into glucose, which enters the blood more rapidly
1 Low blood glucose (hypoglycemia) stimulates release of
GHRH
2 GHRH stimulates secretion of hGH by somatotrophs hGH
3 hGH and IGFs speed up breakdown of liver glycogen into glucose, which enters the blood more rapidly
4 Blood glucose level rises to normal (about 90 mg/100 mL)
1 Low blood glucose (hypoglycemia) stimulates release of
GHRH
2 GHRH stimulates secretion of hGH by somatotrophs hGH
Anterior pituitary 3 hGH and IGFs speed up breakdown of liver glycogen into glucose, which enters the blood more rapidly
4 Blood glucose level rises to normal (about 90 mg/100 mL)
5 If blood glucose continues to increase, hyperglycemia inhibits release of GHRH
1 Low blood glucose (hypoglycemia) stimulates release of
6 High blood glucose (hyperglycemia) stimulates release of
GHRH
GHIH
2 GHRH stimulates secretion of hGH by somatotrophs hGH
Anterior pituitary 3 hGH and IGFs speed up breakdown of liver glycogen into glucose, which enters the blood more rapidly
4 Blood glucose level rises to normal (about 90 mg/100 mL)
5 If blood glucose continues to increase, hyperglycemia inhibits release of GHRH
1 Low blood glucose (hypoglycemia) stimulates release of
6 High blood glucose (hyperglycemia) stimulates release of
GHRH
GHIH
2 GHRH stimulates secretion of hGH by somatotrophs hGH
7 GHIH inhibits secretion of hGH by somatotrophs
3 hGH and IGFs speed up breakdown of liver glycogen into glucose, which enters the blood more rapidly
4 Blood glucose level rises to normal (about 90 mg/100 mL)
5 If blood glucose continues to increase, hyperglycemia inhibits release of GHRH
1 Low blood glucose (hypoglycemia) stimulates release of
6 High blood glucose (hyperglycemia) stimulates release of
GHRH
GHIH
2 GHRH stimulates secretion of hGH by somatotrophs hGH
7 GHIH inhibits secretion of hGH by somatotrophs
Anterior pituitary 3 hGH and IGFs speed 8 A low level of hGH and up breakdown of liver IGFs decreases the rate glycogen into glucose, of glycogen breakdown which enters the blood in the liver and glucose more rapidly enters the blood more slowly
4 Blood glucose level rises to normal (about 90 mg/100 mL)
5 If blood glucose continues to increase, hyperglycemia inhibits release of GHRH
1 Low blood glucose (hypoglycemia) stimulates release of
6 High blood glucose (hyperglycemia) stimulates release of
GHRH
GHIH
2 GHRH stimulates secretion of hGH by somatotrophs hGH
7 GHIH inhibits secretion of hGH by somatotrophs
Anterior pituitary 3 hGH and IGFs speed 8 A low level of hGH and up breakdown of liver IGFs decreases the rate glycogen into glucose, of glycogen breakdown which enters the blood in the liver and glucose more rapidly enters the blood more slowly
4 Blood glucose level rises to normal (about 90 mg/100 mL)
9 Blood glucose level falls to normal (about 90 mg/100 mL)
5 If blood glucose continues to increase, hyperglycemia inhibits release of GHRH
1 Low blood glucose (hypoglycemia) stimulates release of
6 High blood glucose (hyperglycemia) stimulates release of
GHRH
GHIH
2 GHRH stimulates secretion of hGH by somatotrophs hGH
7 GHIH inhibits secretion of hGH by somatotrophs
Anterior pituitary 3 hGH and IGFs speed 8 A low level of hGH and up breakdown of liver IGFs decreases the rate glycogen into glucose, of glycogen breakdown which enters the blood in the liver and glucose more rapidly enters the blood more slowly
4 Blood glucose level rises to normal (about 90 mg/100 mL)
9 Blood glucose level falls to normal (about 90 mg/100 mL)
5 If blood glucose 10 If blood glucose continues to increase, continues to decrease, hyperglycemia inhibits hypoglycemia inhibits release of GHRH release of GHIH
