Problem Statement Diabetes Mellitus
Problem Statement Diabetes Mellitus
millions of people with diabetes. More than 80% of diabetes deaths are recorded in
low and middle-income countries, which are mostly less prepared to
face this epidemic. Deaths due to diabetes could double between 2005 and
2030. It is estimated that in 2004, 3.4 million people died as a consequence of
excess sugar in the blood. Almost half of those deaths correspond to people from
less than 70 years old, and 55% are women.
In the State of Mexico, to mention a few data points, according to the Directorate
General Health Information, during the period 2006-2010, registered 51,950
deaths due to diabetes, with the female gender being more affected. Therefore,
regarding hospital expenses for this condition, during the period of 2005 to 2009, there
26,031 were recorded, with the female gender being the most affected.
488 thousand 700 are men and 572 thousand 600 are women.
causes this disease, so that students have sufficient knowledge about the
prevention of the different types of diabetes mellitus and their ability to identify the signs and
symptoms of this disease
What is the level of knowledge about diabetes mellitus among students of the Bachelor's degree.
The genomics of the multidisciplinary academic division of Jalpa de Méndez (DAMJM)?
4
1.3 Objetivos
1.3.1 General
Evaluate the level of knowledge about diabetes mellitus among students of
the Lic. in Genomics of the multidisciplinary academic division of Jalpa de Méndez
(DAMJM)
1.3.2 Specific
The history of diabetes dates back to ancient times. The first records that
The knowledge about diabetes is found in the Ebers Papyrus (1550 B.C.), which talks about a
therapeutic treatment of polyuria (excessive urination), being mentioned for the first time
the main symptom of diabetes. Demetrius of Apamea (2070 B.C.), created the denomination
diabetes, which means in Greek 'to pass through', since urine does not stay in the body
(excessive urine), but passes through a tube. A century later, in his work "of
"Medicine" Celso (30 B.C.), already knows two fundamental principles of treatment of the
diabetes: diet and muscle work ([Link], 2001). Thus, through the centuries
make great discoveries, until in the year 1869 a doctor with the last name Langerhans,
It is discovered that diabetes occurs because the body is unable to produce insulin. Without
embargo, his greatest contribution was to discover that insulin is created by groupings of
Beta cells in the pancreas. To this day, these cellular groups are known as
Islets of Langerhans.
Another great contribution was made by Joslin in 1923, when he began to treat his
patients with insulin and significantly reproduce the incidence of deaths
([Link], 2001). Due to the high rate of diabetic people in Mexico, this
disease is considered the leading cause of death in our country, as there is 10.9
millions of diabetics, as well as a public health problem according to provided data
through the national center for epidemiological surveillance and disease control of the secretary
In federal health, every 2 hours 11 people die from complications derived from this illness,
the same that registers 176 million sick people worldwide (Druck, 2005). It is said about
hundreds of millions around the world and the people in Asia, Latin America, and Africa are more
6
prone to suffer from this disease. In the United States of North America, one in five
people are diabetic (ADA, 2005). The projection indicates that the increase will continue.
in the number of diabetics.
A high percentage of the adult population in Mexico suffers from this chronic disease.
degenerative. In most cases, people realize they have it when it
the disease is very advanced (Guarque, 2005). In this chapter, it will be disclosed
its characteristics, what it consists of, and what its consequences are. To do this, it will define what
It is diabetes. Diabetes is a systemic, chronic-degenerative disease in nature.
heterogeneous, with varying degrees of hereditary predisposition and with participation of
various environmental factors, characterized by the increase in glucose levels
blood (hyperglycemia), caused by a defect (complete or not) in secretion or action
of insulin and/or resistance to the action of insulin produced by the body itself. (1)
Very rarely do they exceed 130 mg/dL, even when food has been consumed.
very high in sugars or fats. The stability of blood glucose is due to the existence of
extraordinarily fine and sensitive regulatory mechanisms: when a person does not
diabetic consumes food, the substrates they contain are absorbed from the intestine and
they enter the blood, where they raise glucose levels. Such a trend in the increase of
glucose is immediately detected by the insulin-producing cells in the pancreas
that respond with a rapid secretion of it; this, in turn, passes to the cells of the
muscles, from adipose tissue and from the liver, reducing its level in the blood. Once that
glucose has entered the tissues, it is metabolized and produces energy, used to maintain the
functions of the organs and their structure; a similar amount is stored in the liver and in the
muscles.
In a person with diabetes, insulin production is decreased or their
action is lower, preventing glucose from entering the cells and its concentration is
maintains elevated in blood, this excess of glucose in the blood produces a phenomenon of
osmotic diuresis and with it severe dehydration, as well as intense thirst. That is to say, due to the
high levels of glucose in the blood, the kidney, which acts as a filter for glucose, receives
7
On the other hand, the lack of insulin action makes it difficult for the cell to receive the input.
energy coming from sugars, the body tries to obtain it from fats, with
that a mobilization occurs of those last ones that are stored in the tissue
adipose. Therefore, this is one of the causes of weight loss and excessive appetite of
many diabetics. Additionally, disorders in fat synthesis occur,
liver and muscle glycogen, which leads to weight loss, decrease of
cellular immunity, elevation of lipids in the blood, among other metabolic consequences.
These alterations can progress and produce serious situations, such as the
ketoacidosis and hyperosmolar non-ketotic state; the former is more common in type 1 diabetes.
second, in DM2.
Types of diabetes
Type 1 diabetes (T1D).
Type 1 diabetes (also called insulin-dependent, juvenile, or onset in the
childhood). It is most commonly diagnosed in people under 20 years of age, but it can
can occur at any age. In general, it does not affect all members of the same family and
it commonly appears in individuals who are thin or of normal weight. It is characterized by
the body does not produce insulin and the person must administer it daily to maintain
the figures in control parameters. The risk of ketosis is increased in these patients.
pregnancy. Its symptoms are similar to those of type 2 diabetes, but it is usually diagnosed
through prenatal tests, more than because the patient reports symptoms.
Unfortunately, there are no reliable records that provide figures for
prevalence of GDM for ALC, due to the lack of a diagnostic standard. They consist of
that carries out an analysis of various diagnostic studies of DMG in the EU and finds
that the prevalence varies between 1.1 and 14.3%. (2)
It is classified as follows:
• Glucose < 140 mg/dL. The person is categorized as healthy. However, it is
It is necessary to take into account the context of the patient. If they are obese or have some other
assess the patient's context to determine whether it is necessary to start therapy or not
pharmacological. In addition to measuring the glucose level to reach the diagnosis of
In diabetes mellitus, it is important to know the lipid profile since most people
those living with diabetes present dyslipidemias.
HDL cholesterol or high density > 40 mg/dL in men and > 50 mg/dL in women
women.
Prevention
It has been shown that simple lifestyle-related measures are effective.
to prevent type 2 diabetes or delay its onset. To help prevent diabetes of
type 2 and its complications are due to:
achieve and maintain a healthy body weight.
stay physically active: at least 30 minutes of regular moderate-intensity activity
moderate most days of the week; to control weight, it may be necessary to have a
most intense activity.
consume a healthy diet that avoids sugar and saturated fats.
avoid tobacco use, as it increases the risk of developing diabetes and diseases
cardiovascular.
Diabetes Treatment.
The fundamental objectives of treatment for all types of diabetes are:
Relief of symptoms,
Maintain metabolic control,
Improvement of quality of life,
Prevention of acute and chronic complications,
Treatment of diseases that accompany diabetes,
Decreased mortality.
Clinical picture.
The forms of clinical presentation are very varied and can be summarized in the
following:
Metabolic presentation. Insulin is one of the main hormones.
anabolic substances in the body and consequently, their dysfunction affects not only metabolism
of glucose, but also of fats and proteins. The assimilation of glucose in the
muscle and fat tissue decreases significantly or disappears. It not only stops being stored.
glycogen in the liver and muscle, but its reserves are completely emptied.
Fasting blood sugar can reach very high levels. When this happens,
produce its elimination through urine (glucosuria). If the glucose to be eliminated is very
elevated, polyuria occurs (excess urine), which leads to an intense loss of water and
electrolytes, which can cause diabetic coma. Intense thirst (polydipsia) appears.
due to water loss, and an increase in appetite (polydipsia), with weight loss (which
it can be 4-6 Kg in a month), being this the classic triad of diabetes: polyuria,
polydipsia and polyphagia. This symptomatology is often accompanied by asthenia; if it concerns children.
they lose the desire to play and remain much quieter than usual. The coma
diabetes can also occur due to ketoacidosis: the deficiency of insulin causes a
14
excessive destruction of fat cells and thereby raises the concentration of fatty acids
free.
Non-metabolic presentation. Metabolic symptoms may be minimal or present.
absent and the diagnosis is suspected due to infections or complications of the disease.
The patient reports having experienced polyuria, polydipsia, and increased appetite throughout their
life. There is usually no asthenia or it is very discreet, and weight loss is not constant. In others
in some cases, the disease is diagnosed by the ophthalmologist upon noticing lesions in the retina that
they suggest diabetic retinopathy. Other times the diagnosis is made by the dermatologist due to the
appearance of any characteristic skin lesion, such as diabetic dermopathy. In others
Sometimes the reason for the consultation is bulbar itching that can be caused by the
hyperglycemia or due to vaginal fungal overinfection, generally Candida albicans. The
infections are more common among diabetics than in the rest of the population. They are
especially frequent are genitourinary infections and respiratory infections.
Asymptomatic presentation. In many Western countries, it constitutes the most common form.
frequent diagnosis of non-insulin-dependent diabetes mellitus, which is usually determined by occupational medical exams.
In this case, treatment with multiple insulin injections is essential for life.
15
Gestational Diabetes.
Gestational diabetes is diagnosed for the first time during pregnancy. The
pregnancy becomes a precipitating factor for diabetes in women who present
relatives with the disease, overweight or obesity. Usually this type of diabetes is
treated with appropriate dietary plans and insulin. After childbirth, this type of diabetes
disappears, although, the woman greatly increases the risk of developing type 2 diabetes in the long term
deadline.
Its symptoms are similar to those of type 2 diabetes, but it is usually diagnosed.
through prenatal tests, more than because the patient reports symptoms.
Prevention.
It has been shown that simple lifestyle-related measures are effective.
to prevent type 2 diabetes or delay its onset. To help prevent diabetes
type 2 and its complications are due to:
Achieving and maintaining a healthy body weight.
17
Diabetes is expected to become the seventh leading cause of death worldwide by the year 2030.
death.
Ketoacidosis: a serious medical condition due to a very low level of insulin, and due to
elevated levels of glucose and ketone bodies in the urine.
Cholesterol: a substance similar to fat that is found in the bloodstream and
in the tissues. The body uses cholesterol to produce hormones and form cell walls.
21
However, too much cholesterol can cause a disease that harms the
blood circulation.
Good cholesterol: high-density lipoprotein (HDL) cholesterol.
it helps the liver to eliminate all the cholesterol from the body. The higher its level
the good cholesterol, the less likely you are to develop heart disease.
Long-acting insulin: insulin that provides the body with a level of insulin.
low and constant during the day and night; it can be administered through injections of
intermediate or long-acting insulin, or through continuous releases of insulin from
quick action with an insulin pump.
Rapid-acting insulin: insulin that acts faster and for a
shorter time period compared to regular human insulin; it is prepared at
modify the chemical structure of the insulin molecule.
Rapid-acting insulin: rapid-acting insulin (regular or fast-acting) that
provides the necessary insulin stimulus to stop the increase in glucose levels
blood that is produced after meals; it can be administered as an injection
after meals or with a dose after meals through a pump of
insulin.
Regular human insulin: the oldest form of fast-acting insulin. With the
regular human insulin; meals are ingested 30 minutes after the injection. In the
newer rapid-acting insulin treatments, such as NovoLog (insulin aspart [r
DNA origin injection), meals can be ingested within 5 to 10 minutes.
Gangrene: Death of body tissues. It is caused by loss of blood flow.
for obstruction of the arteries, especially of the legs and feet.
Gastroparesis: It is a type of gastrointestinal autonomic neuropathy that affects the
motility and emptying of the stomach. For this reason, food is not well digested and does not
they continue their normal course in the stomach, resulting in vomiting, nausea, and a feeling of
postprandial fullness. See also. Neuropathy.
Gene: Basic unit of inheritance. Genes are made up of DNA (deoxyribonucleic acid).
Glaucoma: Eye disease associated with increased pressure inside the eye.
Glaucoma can damage the optic nerve and cause vision impairment and blindness.
Glucose: Level of glucose in the blood. It can also be called glycemia.
It is performed in a clinical laboratory with a blood sample taken from a peripheral vein.
Some devices measure blood glucose in whole blood and others in serum or plasma. If the sample
comes from puncturing the pulp of one of the fingers and the drop of blood obtained and
applied to a strip is read on a small device (glucometer), the result is called
blood glucose monitoring.
after fasting for 8 to 14 hours. The normal result is between 60 and 110 mg/dl. The
A fasting blood glucose level greater than or equal to 126 mg/dl makes the diagnosis of diabetes.
mellitus. If the result is between 110 and 125 mg/dl, it is diagnosed as fasting blood glucose.
changed.
Two-hour post-glucose load blood sugar: Blood glucose level that is measured
2 hours after ingesting 75 grams of glucose (in children 1.75 gr per kilo of weight)
dissolved in water. The normal result corresponds to less than 140 mg/dl. The finding of
a glucose level two hours post-glucose load equal to or greater than 200 mg/dl establishes the diagnosis of
blood sugar level after meals and with this determine if any adjustment is necessary in the
treatment or in the food.
Glucagon: It is one of the counter-regulatory hormones of insulin that raises the
blood glucose level. When the body needs more glucose in the blood, the
Alpha cells of the pancreas (in areas known as islets of Langerhans) produce glucagon.
Sometimes injectable glucagon is used in cases of severe hypoglycemia. The injection
Glucagon helps to raise blood glucose levels.
Glucose: A simple sugar present in the blood. It is the main source of energy.
of the body. It is also called dextrose. See also below: Blood glucose.
Glucosuria: Presence of glucose in the urine. A normal person should not contain.
glucose in your urine. Glucosuria usually occurs in poorly controlled diabetes.
Glucose begins to appear in the urine when blood glucose levels are above 160-180 mg/dl;
This level is referred to as the 'renal threshold' for glucose.
Some people may have a very low renal threshold for glucose and present
positive glucosuria with normal blood sugar levels (renal glucosuria).
25
3.2 Population
It was carried out in the Multidisciplinary Academic Division of Jalpa de Méndez with the
first semester students of the Degree in Genomics.
117 students from the academic division of Jalpa de Méndez that will be held with a
confidence level of 96% and an error margin of 0.05 giving a total of 90 students
(117).
3.4 Sample
It was carried out by random clusters.
Inclusion
First semester students of the Bachelor in Genomics aged 18 to 19 years.
Students of both female and male sex.
Students who are present at the time of conducting the survey.
3.5.1 Exclusion
Those students who did not wish to participate in the survey
27
3.5.2 Deletion
Students who were not present at the time of the survey application
3.6 Instrument
A questionnaire format will be used for data collection whose preparation is
based on the issue under study (DKQ24 questionnaire).
3.7 Procedure
Data collection will be carried out through the technique of a survey. The
which will apply to the first semester students of the Genomics degree in the division.
multidisciplinary academic from Jalpa de Méndez who are between 18 and 20 years old.
A survey consisting of 24 questions about knowledge will be used as an instrument.
basics of the disease (10 items), blood glucose control (7 items) and prevention of
complications (7 items), of which only basic knowledge was taken from the
disease (6 items), glucose control (5 items) and prevention of
complicaciones (3 ítems) ya que estas son las preguntas que nos llevaran a lograr el objetivo
general. The questions are closed-ended, with answer options yes, no, and I don't know. The level of
knowledge is classified as sufficient with 10 or more correct answers (70% or more of the total)
correct answers) and insufficient knowledge with 9 correct answers or less.
28
2-Is the common cause of diabetes the lack of effective insulin in the body?
A) YES B) NO C) I DON'T KNOW
3- Is diabetes caused by the kidneys not being able to keep sugar out of
the urine?
A) YES B) NO C) I DON'T KNOW
10- Aren't the foods for diabetics the same as for other people?
A) YES B) NO C) I DON'T KNOW
GLUCOSE CONTROL
11-Will regular exercise increase the need for insulin or other medication for
diabetes?
29
12- Is a blood sugar level of 210 on a fasting blood test very high?
A) Yes B) NO C) I DON'T KNOW
PREVENTION OF COMPLICATIONS
18- Does diabetes often cause poor circulation?
A) YES B) NO C) I DON'T KNOW
20- Should diabetics take extra care when cutting their toenails?
the feet?
A) YES B) NO C) I DON'T KNOW
21--Should a person with diabetes clean a cut first with iodine and
Alcohol?
A) Yes B) NO C) I DON'T KNOW
23- Can loss of sensitivity in hands and feet occur due to diabetes?
A) YES B) NO C) I DON'T KNOW
24- Are socks and elastic stockings not recommended for diabetics?
30
Table No. 1
Is eating a lot of sugar and other sweet foods a cause of diabetes?
Percentage
Frequency Percentage Valid percentage accumulated
Source: direct n: 85
Graph No. 1
Source: table No 1
The results of the first reagent are shown in graph No. 1: where a total of
22.4% of students do not agree that high sugar consumption is not synonymous with diabetes.
3.6 is not aware of this possible cause, while 73.8% agrees with the cause of
diabetes.
Table No. 2
The common cause of diabetes is the common lack of effective insulin in the
body?
Percentage Percentage
Frequency Percentage valid accumulated
Graphic No 2
34
Source: table No 2
In reagent number 2, the following results were obtained: 3.5% do not suggest.
Some response when marking I don't know how to respond, 14.1% indicated no to the common absence of
effective insulin in the body is a cause of diabetes, and a large part of the studied population
he referred that it is one of the possible causes with an 82.4%.
Table No 3
Do the kidneys produce insulin?
Percentage Percentage
Frequency Percentage valid accumulated
Source: direct n: 85
Graph No 3
35
Source: table No 3
Reagent No. 3: it can be observed that 10.6% responded with 'I don't know' about the
insulin formation in the kidneys, while 25.9 chose yes as the origin of the
insulin in the kidneys, and 63.5% reported that they do not.
Table No 4
Percentage
Frequency Percentage Valid percentage accumulated
Graphic No. 4
36
Source: table No 4
In reagent no. 4, they say that there are not two types of diabetes mellitus, 3.5%.
while 4.7% are unaware, unlike the other 91.8% who assert that they do exist
two types of diabetes mellitus, so it can be said that more than half of the students
They identify the types of diabetes that exist.
Table No 5
Percentage
Frequency Percentage Valid percentage accumulated
Chart No. 5
37
Source: table No 5
6.0% are unaware if diabetes mellitus is hereditary, while another 11.9% assert that it is not.
it is hereditary while 82.1% affirm that diabetes mellitus is transmitted in a way
hereditary, this means that the vast majority of genomics students assert that the
diabetes mellitus is transmitted heredity.
Table No 6
Can diabetes be cured?
Percentage
Frequency Percentage Valid percentage accumulated
Valid no 75 88.2 89.3 89.3
Source: direct n: 85
Graph 6
38
Source: table No 6
4.8% of students are unaware if diabetes mellitus is curable, the other 6.0%
ensures that if it is curable, while 89.3% states that diabetes mellitus is not curable.
It means that the vast majority of students claim that diabetes cannot be cured.
Table No 7
Is a blood sugar level of 210 in a fasting test very high?
Percentage Percentage
Frequency Percentage valid accumulated
Source: direct n: 85
Chart No 7
Source: table No 7
39
Reagent 7: It is illustrated that 22.4% say they are unaware that the parameter of 210 is high in
fasting, 7.1% claim that they do not agree and finally 70.6% favored that the level of
fasting glucose is 210 mg/dl.
Table No 8
Is medicine more important than diet and exercise to control my
diabetes?
Percentage Percentage
Frequency Percentage valid accumulated
Source: direct n: 85
Graph No 8
40
Source: table No 8
Reagent 8. The results show that 4.7% do not know about this.
Aspects, of the respondents 23.5% took it as 'yes' to agree.
with the previous condition, as long as 71.8 states that they are not in
concordance.
Table No 9
Percentage Percentage
Frequency Percentage valid accumulated
Source: direct n: 85
Graphic No 9
41
Source: table No 9
Table No 10
Percentage Percentage
Frequency Percentage valid accumulated
Source: direct n: 85
Chart No. 10
42
Source: table No 10
16.5% do not know if sweating and trembling are signs of diabetes. Regarding
that 35.3% have no relationship at all regarding this and the other 48.2 states
that 'yes' are signs of diabetes.
Table No 11
Percentage Percentage
Frequency Percentage valid accumulated
Source: direct n: 85
43
Graphic No 11
Source: table No 11
Reagent 11. It shows that urinating a lot and having excessive thirst are
Signs of low blood glucose at 16.7% reported that they did not, 33.3%
50.0% are unaware of this situation and state that they maintain some relationship.
Table No 12
Percentage Percentage
Frequency Percentage valid accumulated
Direct source n: 85
44
Graph No 12
Source: table No 12
Reagent 12. The studied population only took 'yes' as a reference in their responses.
and "no", therefore 7.1% rated as "no" regarding whether cuts and scrapes heal.
With slowness in these types of people with this illness, 92.9% affirmed that it is.
possible as a consequence of diabetes is the slow healing of these wounds.
Table No 13
Percentage Percentage
Frequency Percentage valid accumulated
Source: direct n: 85
45
Graph No 13
Reactive 13: 5.9% of the studied population stated that the kidney can be damaged.
Due to diabetes mellitus, 27.1% claim to be unaware if these get damaged, while the
67.1% state that the kidneys do not get damaged.
Table No 14
Percentage Percentage
Frequency Percentage valid accumulated
Source: direct n: 85
46
Graphic No 14
Reagent 14. It is possible to estimate that 3.5% state that they do not
They present loss of sensitivity in the feet and hands in diabetic people.
18.8% have no knowledge at all and 77.6% claim that they do maintain a relationship.
some.
Chapter V. Discussion
5.1 Discussion
However, it is still difficult to find a health service that puts equal emphasis on the
educational aspects that in caregiving, despite the results of the research
conducted in the field of diabetes mellitus show, in a deficient manner, that due to
ignorance of at-risk groups increases their prevalence, due to lack of knowledge, lack of
skills and motivations to face therapeutic demands.
The present study shows that the basic concepts about Diabetes at a level of
knowledge in first cycle students is practically the same as that presented by studies
carried out on diabetic patients with very low education (incomplete primary education
mainly) because the findings of knowledge about diabetes that our expose
university students in the early cycles make us reflect on the little
diabetes education that people in the communities could have
48
They belong. The high levels of knowledge regarding inheritance draw attention.
diabetes and the importance of food selection and the way of preparing them in control
of the patient. In this aspect, the students responded better, probably due to education
the formality that the students have had during their learning process has had to do with
diet aspects, on the other hand considering the high incidence of diabetes mellitus in
Our population, it was to be expected that they would have knowledge about the inheritance of this
disease. The relationship between untreated diabetes and hereditary factors in diabetes is
aspects with responses similar to those observed in a study conducted on healthcare personnel
where probably due to the students' experience by having been in contact with
Diabetic relatives may have been influenced to answer correctly and there was no existence.
significant statistical difference between the different school groups. The rest of
Basic knowledge about diabetes mellitus obtained better grades, very
probably secondary to the fact that the curriculum of the Genomics program has contemplated
several students who had preparatory studies with a similar profile.
The purpose of the work was not to evaluate the increase in scientific concepts about
diabetes mellitus in the genomics students, but the knowledge they had presented
students of the course about what diabetic patients should know for this
potentially be able to understand them better and interfere in the investigation. So
it was interesting to observe the increase in knowledge, undeniably secondary
to his teachings of the curriculum, but also, the lack of notions in areas that
Frequently, the diabetic patient might question the student or during their activity.
professional.