Lymphedema Algorithm — Evaluation Flowchart
Clinic quick-reference with directional arrows
START — Patient with limb swelling
Confirm laterality and chronicity; obtain vitals; identify immediate red
flags while rooming.
Rule-Outs & Red Flags (do first)
• Acute unilateral pain/swelling → Venous duplex to r/o DVT
• Fever/erythema/warmth → Treat cellulitis; defer MLD/compression over hot
area
• CHF/renal/hepatic decompensation → Stabilize before CDT
Focused History
Onset/trajectory; surgical/RT/trauma/infection risks; symptoms (heaviness,
tightness, diurnal change); cellulitis history; prior CDT/MLD/compression;
impact on ADLs/QOL.
Targeted Exam & ISL Stage
Distribution (dorsum hand/foot, digits), Stemmer sign, pitting vs fibrosis,
skin changes; venous signs. Stage 0–III. Capture photos.
Objective Measures
Circumferences/volume → %/cm asymmetry; BIS/L-Dex if available (∆ from
baseline). Record PRO (LLIS/LYMQOL) and pain score.
c suspected NO/UNCERTAIN →
udy; labs/echo Lymphoscintigraphy (con
Diagnosis clear from H&P + measures?
tributors. physiology); ICG lymphog
(pattern/mapping); MR
lymphangiography (anato
YES → Initiate CDT
Start Phase I CDT: MLD, short-
stretch bandaging, skin care,
This tool supports, not replaces, clinical judgment.exercise; fit compression
© Lymphedema Expert (UE 20–30;
LE 30–40 as tolerated).