DETAILED LESSON PLAN IN GRADE 8
Division: Antique Grade Level: Grade 8
Name of Teacher: Jeralyn C. Ogatis Learning Area: Biotechnology
Teaching Date & Time: Week 3 (Day 1-2) Quarter: 3rd Quarter
Duration: 60 minutes
Learning Area: Biotechnology 8 Quarter: 3 Week: 3
I.
OBJECTIVES
A. Content Understand the concept of genetic material (DNA), how
Standard it functions, and how it can be manipulated in scientific
processes like genetic engineering.
B. Performance Explain how genetic material is manipulated through
Standard various methods and recognize its real-life application
in agriculture, medicine and technology.
C. Learning Discuss How Genetic Material is Manipulated (S8LT-
Competency with Ie-4)
Code
D. Learning At the end of the lesson, the Grade 8 learners should be
Objectives able to perform the following tasks with 80%
proficiency:
1. Describe what genetic material is and explain how it
can be manipulated.
2. Illustrate a basic process of genetic material
manipulation through drawing.
3. Express opinion about the benefits and risks of
manipulating genetic material.
II. CONTENT
Topic: How Genetic Material is Manipulated
Subject Science, Ethics and Social Studies, Language Arts
Integration:
Value Focus: Cooperation/ Participation
Critical Thinking
Responsibility
III. LEARNING
RESOURCES
A. References
A.1. Teacher’s Essential Learning Competencies of DepEd for Special
Guide Pages Science Program
A.2. Learner’s None
Material Pages
A.3. Textbook
Pages
B. Other Learning PowerPoint Presentation, Video Presentation, Printed
Resources materials of DNA structure and genetic modifications,
paper and colored pen
IV. TEACHER’S ACTIVITIES/ RESPONSES STUDENT’S
PROCEDURES ACTIVITIES/
RESPONSES
Preliminaries (Expected Answers)
Greetings Good morning class Good morning Ma’am
Ogatis
May I request anyone from the group to please (one student will
Prayer lead the prayer? volunteer)
Classroom May I request everyone to please pick up the
manageme rubbish under your chair and after that, please
nt arrange your chair and sit quietly
Checking
of Before we start, may I request the class monitor (The classroom monitor
Attendance to please check the attendance and submit to me will check the attendance)
later on the name of absentees for today
Lesson Proper
a. Elicit Last time, we’ve discussed about the different tools
used in genetic engineering together with its
corresponding descriptions, right?
Any idea about it? Yes ma’am.
Yes, (name of the student) Last time we discussed
about the different tools
used in genetic
engineering and its
application in the real-
world.
Very good.
“What do you think DNA is and why it is important?”
Yes, (name of the student) DNA is the molecule that
carries the genetic
instructions essential for
the growth, development,
functioning, and
reproduction of all living
organisms.
Very good.
(Will show a simple image of DNA)
Have you heard of genetically modified organisms
(GMOs)?
Yes, (name of the student) Yes Ma’am.
b. Engage I have here a video presentation in order for us to better
understand the concepts of our lesson for today which is
all about how DNA can be manipulated. But before
that, may I request anyone from the group to read our
learning objectives for us to be guided for today’s
lesson?
Yes, (name of the student) One student will read the
learning objectives.
(The video presentation will play)
(https://youtu.be/6tw_JVz_IEc?
si=F8VWBpSz59INDPcx)
Guide Questions:
1. What did you find interesting about the video?
Yes, (name of the student) I found it interesting how
CRISPR can precisely
edit specific parts of
DNA, making it possible
to create GMOs that are
more resistant to diseases,
pests, or harsh
environmental conditions.
Impressive.
2. What did you learn about genetic modification?
Yes, (name of the student) I learned that genetic
modification involves
changing the DNA of an
organism to give it new
traits.
Amazing.
c. Explore Let me introduce to you the genetic material (DNA)
which is a molecule that contains the instructions for all
living organisms to grow, develop, and function.
Did you know that DNA is a blueprint of life? Yes, ma’am.
Why is it so?
Yes, (name of the student) Because it stores the
genetic materials ma’am.
Okay, very good. DNA is like a blueprint for life,
storing all the information needed to build and maintain
an organism. I have here an illustration of a DNA,
please observe closely the different parts of it because
later on, I will ask anyone from the group what are the
four nitrogenous bases of the DNA.
I will show the key features of the DNA through a
PowerPoint Presentation, its location, and function.
The importance of DNA structure is also included in the
presentation for a smooth flow of the lesson.
A short demonstration of how DNA can be altered
Step1: Cutting DNA
Scientists use tools like CRISPR to cut specific
sections of DNA
Example Drawing: Show a DNA strand with a
cut marked by scissors.
Step 2: Inserting of new gene
A new gene is added where the cut was made, (The students will
giving the organism new traits. participate in the said
Example Drawing: Highlight the new gene as short demonstration)
colored segment added to the DNA strand.
Step 3: Reconnecting DNA
The DNA is reconnected, now containing the
inserted gene.
Example Drawing: A complete DNA strand with
the new gene integrated.
This process allows scientists to create modified
organisms, like pest-resistant plants or medicines for
diseases.
d. Explain PowerPoint presentation is also presented as the guide
for a smooth flow of the topic including the genetic
engineering and gene editing.
What is genetic engineering?
Kindly read, yes (name of the student) Is the process of directly
modifying an organism’s
DNA using
biotechnology to
introduce, remove, or
alter specific genes,
allowing scientists to give
the organism new traits or
improve existing ones for
applications in medicine,
agriculture, and research.
How about gene editing?
Yes, (name of the student)
Is a technique that allows
scientists to make precise
changes to an organism’s
DNA by adding,
removing, or altering
specific genetic
sequences, often using
tools like CRISPR, to
correct genetic disorders
or enhance certain traits
Very good.
Applications:
A. Genetically Modified Plants
Scientists create pest-resistant crops by
inserting genes that produce natural
insecticides. For example, Bt cotton contains a
gene from bacteria that protects it from pests.
Other crops, like golden rice, are modified to
contain higher levels of vitamins, addressing
nutrient deficiencies
B. Genetically Modified Animals
Animals are modified for faster growth or
disease resistance. For example, genetically
engineered salmon grow twice as fast as regular
salmon.
Livestock may be edited to resist diseases,
improving animal welfare and food production.
3. Gene Therapy
Gene editing is used to treat genetic disorders in
humans. For example, CRISPR has been tested
to fix mutations causing diseases like sickle cell
anemia or cystic fibrosis.
This method targets specific faulty genes in
patients, offering personalized treatments.
e. Elaborate Positive and Negative Impacts of Genetic
Manipulation
Positive Impacts:
Increased Food Production: Genetically
modified crops, like pest-resistant corn or
drought-tolerant rice, improve yields and ensure
food security in harsh conditions.
Medical Advances: Gene therapy and genetic
engineering help treat diseases like cancer and
genetic disorders, improving health outcomes.
Environmental Benefits: Reduced pesticide use
in genetically modified crops minimizes
environmental damage.
Nutritional Improvements: Crops like golden
rice are enhanced with essential vitamins,
addressing malnutrition.
Negative Impacts:
Ethical Concerns: Modifying genes in humans
or animals raises questions about “playing
God” and potential misuse for non-ethical
purposes, such as designer babies.
Environmental Risks: Genetically modified
organisms (GMOs) may harm ecosystems by
affecting biodiversity or creating super weeds
resistant to herbicides.
Health Risks: Long-term effects of consuming
GMOs are still debated, with concerns about
allergies or unintended consequences.
Economic Disparities: GMO technology is often
patented, making it expensive and inaccessible
for small-scale farmers in developing countries.
f. Evaluate
With your seatmate, draw or illustrate a process of
genetic modification (e.g., inserting a gene into a plant The students will group
or using CRISPR) themselves and pass their
work on time.
g. Extend Assignment:
Research an example of genetic manipulation and share
what you have learned with the class.
References: www.genetics.utah.edu
www.nigms.nih.gov
Genetic Science Learning Center. (2020). Introduction to Genetic Engineering.
National Institute of Health. (2020). How Genetic Engineering Works.
PREPARED BY: CHECKED AND VERIFIED BY:
JERALYN C. OGATIS JOINVILLE M. OMAY
Student Intern Cooperating Teacher
