ExperimentNo.9 Date:…………………….

PREPARATION AND STANDARDIZATION

OF CERIC AMMONIUM SULPHATE
AIM: To prepare and standardize 0.1M cerric ammonium sulphate.

REFERENCE:

1) Practical pharmaceutical chemistry, Fourth edition-part one, edited by A H BECKETT,

J B STENLAKE, CBS Publishers and Distributors, 2005, P-194,195

2) Indian Pharmacopoeia by ministry of health and family welfare, Govt. of India,8 th edition
vo.1I, 2018, PP 967.
REQUIREMENTS:
Cerric ammonium sulphate, sulphuric acid, arsenic trioxide, sodium hydroxide(8%w/w), osmic acid
solution, sodium oxalate, ferroin sulphate solution and distilled water.

PRINCIPLE:

Cerium sulphate is a power full oxidizing agent in acid solution (1-8N). It is bright yellow
color and corresponding cerium salt form by reduction is colorless strong solutions are self
indicating. However since dilute solutions are used hence indicators are used for observation of
end point. Arsenic trioxides used as primary standard in presence of sulphuric acid and osmic
acid using ferroin sulphate as an indicator for standardization of the solution. The
standardization depends on the reactions expressed by the following equations:
PROCEDURE:

Preparationof 0.1M cerric ammonium sulphate

Dissolve 65g of cerric ammonium sulphate, with the aid of gentle heat, in a mixture of 30ml of
sulphuric acid and 500ml of water. Cool, filter the solution, if turbid, and dilute to 1000ml with
water .Standardize the solution in the following manner.

Standardization of 0.1M cerric ammonium sulphate

Weigh accurately about 0.2 g of arsenic trioxide, previously dried at 105°for 1hour, and transferred
to a 500 ml conical flask. Wash down the inner walls of the flask with 25 m1 of a 8.0 per cent w/v
solution of sodium hydroxide, swirl to dissolve, add 100 ml of water and mix. Add 30 ml of dilute
sulphuric acid, 0.15 ml of osmic acid solution, 0.1 ml of ferrroin sulphate solution and slowly titrate
with the eerie ammonium sulphate solution until the pink colour is changed to a very pale blue,
adding the titrant slowly towards the end-point. 1 ml of 0.1 M eerie ammonium sulphate is equivalent
to 0.004946 g ofAs20 3.

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 OBSERVATION TABLE
S.NO. Burette Reading (ml) Average volume
Initial (a) Final (b) Net reading consumed
(b-a) (1+2+3 / 3)
1.
2.
3.

Calculation:

Weight x Standard Molarity

M = --------------------------------------------------
Volume consumed X Equivalent Factor

RESULT:

19