GUJARAT TECHNOLOGICAL UNIVERSITY
Pharm.D.
1st year
SubjectName: Pharmaceutics
SubjectCode: 818802
Scope: This course is designed to impart a fundamental knowledge on the art and science of formulating
different dosage forms. It prepares the students for most basics of the applied field of pharmacy.
Objectives:
Upon the completion of the course the student should be able to:
a. know the formulation aspects of different dosage forms;
b. do different pharmaceutical calculation involved in formulation;
c. formulate different types of dosage forms; and
d. appreciate the importance of good formulation for effectiveness.
TeachingScheme EvaluationScheme Total
Theory Tutorial Practical Total Theory Practical Marks
External Internal External Internal
2 1 3 6 70 30 70 30 200
Sr. No. CourseContents Hours ModuleW
eightage
1 a. Introduction to dosage forms - classification and definitions 6 10%
b. Prescription: definition, parts and handling
c. Posology: Definition, Factors affecting dose selection. Calculation
of children and infant doses.
2 a.
Historical back ground and development of profession of pharmacy 2 3%
and pharmaceutical industry in brief.
3 Development of Indian Pharmacopoeia and introduction to other 2 3%
Pharmacopoeias such as BP, USP, European Pharmacopoeia, Extra
pharmacopoeia and Indian national formulary.
4 Weights and measures, Calculations involving percentage solutions, 5 8.5%
allegation, proof spirit, isotonic solutions etc.
5 Powders and Granules: Classification advantages and disadvantages, 8 13.5%
Preparation of simple, compound powders, Insufflations, Dusting
powders, Eutectic and Explosive powders, Tooth powder and
effervescent powders and granules.
6 Monophasic Dosage forms: Theoretical aspects of formulation 7 11.5%
including adjuvant like stabilizers, colorants, flavours with examples.
Study of Monophasic liquids like gargles, mouth washes, Throat
paint, Ear drops, Nasal drops, Liniments and lotions, Enemas and
collodions.
7 Biphasic dosage forms: Suspensions and emulsions, Definition, 6 10%
advantages and disadvantages, classification, test for the type of
emulsion, formulation, stability and evaluation.
8 Suppositories and pessaries: Definition, advantages and 4 6.5%
disadvantages, types of base, method of preparation, Displacement
value and evaluation.
9 Galenicals: Definition, equipment for different extraction processes 5 8.5%
like infusion, Decoction, Maceration and Percolation, methods of
preparation of spirits, tinctures and extracts.
10 Pharmaceutical calculations. 6 10%
11 Surgical aids: Surgical dressings, absorbable gelatin sponge, sutures, 3 5%
ligatures and medicated bandages
12 Incompatibilities: Introduction, classification and methods to 6 10%
overcome the incompatibilities.
CourseMaterials: (Latest edition)
Text books
a. Cooper and Gunns Dispensing for pharmacy students
b. A text book Professional Pharmacy by N.K.Jain and S.N.Sharma.
Reference books
a. Introduction to Pharmaceutical dosage forms by Howard C. Ansel.
b. Remington’s Pharmaceutical Sciences.
c. Register of General Pharmacy by Cooper and Gunn.
d. General Pharmacy by M.L.Schroff.
Pharm.D.
1styear.
PHARMACEUTICS
Practical(3 Hours/ Week, 6 Credits, 90 Hours)
Sr. Experiments
No.
1 Syrups
a. Simple Syrup I.P b. Syrup of Ephedrine Hcl NF c. Syrup Vasaka IP d. Syrup of ferrous
Phosphate IP e. Orange Syrup
2 Elixir
a. Piperizine citrate elixir BP b. Cascara elixir BPC c. Paracetamol elixir BPC
3 Linctus
a. Simple Linctus BPC
a. b. Pediatric simple Linctus BPC
4 Solutions
a. Solution of cresol with soap IP b. Strong solution of ferric chloride BPC c. Aqueous Iodine
Solution IP d. Strong solution of Iodine IP e. Strong solution of ammonium acetate IP
5 Liniments
a. Liniment of turpentine IP*
a. b. Liniment of camphor IP
6 Suspensions*
a. Calamine lotion b. Magnesium Hydroxide mixture BP
7 Emulsions*
a. Cod liver oil emulsion
a. b. Liquid paraffin emulsion
8 Powders
9Powde Suppositories suppositories
rs
10 Incompatibilities a. Mixtures with Physical b. Chemical & Therapeutic incompatibilities
Eutecti
c
powder
CourseMaterials:
Text Book & Reference book: (Latest edition)
1. Practical Pharmaceutics, R. S. Gaud & G. D. Gupta
2. A practical book of Pharmaceutics I, Dr. Sanjar Alam & Dr Jaganath Sahoo
3. A practical Handbook of Pharmaceutics, Dr. A. A. Hajare & Dr D. A. Bhagwat
4. Dispensing Pharmacy, R. M. Mehta
5. Indian Pharmacopeia and U S Pharmacopeia
6. The theory and practice of industrial pharmacy, leon lachman and Herbert A.liebarman.
Scheme of PracticalExamination
Internal/Sessional External
Synopsis 05 15
MajorExperiment 10 25
MinorExperiment 03 15
Viva 02 15
Max.marks 20 70
Duration 3 hours 4 hours
Note: Total sessional marks is 30 (20 for practical sessional plus 10 marks for regularity, promptness, viva-
voce and record maintenance).
