Proficient Learning APP 1
Epidural Anesthesia — Comprehensive Academic Notes
Title: Epidural Anesthesia – Technique, Advantages, and Clinical Insights
Prepared by: Department of Anesthesiology & Pain Medicine
Author: Proficient Learning App | Academic Notes Series
1. Learning Objectives
At the end of this topic, learners will be able to:
• Describe the epidural space anatomy and technique.
• Differentiate epidural from spinal anesthesia.
• Discuss clinical indications, complications, and management.
2. Introduction
Epidural anesthesia is a regional anesthesia technique involving deposition of local
anesthetic in the epidural space, producing segmental anesthesia. It allows titration
of dose and continuous analgesia via catheterization.
3. Anatomy of the Epidural Space
• Located outside the dural membrane, extending from the foramen magnum
to the sacral hiatus.
• Contains fat, veins, lymphatics, and nerve roots.
• Identified by the loss-of-resistance technique during needle insertion.
4. Technique
1. Patient positioned sitting or lateral.
2. Identify L2–L3 or L3–L4 interspace.
3. Insert Tuohy needle perpendicular to skin.
4. Detect loss of resistance to air/saline → epidural space reached.
Proficient Learning APP 2
5. Catheter may be advanced 3–5 cm for continuous infusion.
5. Drugs Used
Drug Concentration Duration
Bupivacaine 0.25–0.5% 2–4 h
Ropivacaine 0.2–0.5% 2–4 h
Lidocaine 2% 1–2 h
Adjuvants Fentanyl, Morphine, Clonidine Prolonged action
6. Advantages
Titrable and prolonged anesthesia
Postoperative pain relief
Less hypotension than spinal
Useful in obstetric analgesia and prolonged surgeries
7. Complications
• Accidental dural puncture → headache
• Hypotension
• Infection or abscess formation
• Accidental intravascular injection → systemic toxicity
• Catheter misplacement or migration
8. Differences Between Spinal and Epidural
Feature Spinal Epidural
Injection Site Subarachnoid space Epidural space
Volume Required 2–4 mL 10–20 mL
Onset 2–5 min 10–20 min
Proficient Learning APP 3
Feature Spinal Epidural
Catheter Use Not possible Possible
Duration Limited Adjustable
9. Clinical Applications
• Obstetric analgesia (labor pain control)
• Postoperative pain management
• Thoracic and abdominal surgeries
• Chronic pain procedures
10. References
1. Miller RD, Anesthesia, 9th Edition.
2. Morgan GE, Clinical Anesthesiology, 7th Edition.
3. Barash PG et al., Handbook of Clinical Anesthesia, 2021.