Roll no: J4
Appendix -1
A typical format for the assessment
of an Assignment-2
MET,INSTITUTE OF PHARMACY
Name of the College:
Name ofthe Student:
Roll no of the Student:
2024-2025
Academic Year of the Student:
BIOCHEMISTR Y& CLINICAL PATHOLOGY
Name of the Subject:
Title of the Assignment: Pathological report of Lipid Profile & CBC
14/11/2024
Date on which the Assignment was given:
Date on which the Assignment was submitted: 9/h2/2024
MRS. KIRAN S. DUBE
Name & Designation of the Evaluator:
Score out
Assessment Criteria Score Comments if any
of 5/10*
a. Relevance with the content
b. Use of resource material
c. Organization & mechanical accuracy
d. Cohesion & coherence
e. Language proficiency & Timely submission
Total Score (Out of 25)
Pkearaan
Ta12/2024
Signature of the Student with Date Signature of the Teacher with Date
Directions for markgrading: 5- Excellent; 4 -Very Good; 3- Good; 2- Satisfactory; 1-Poor
*Total Score (out of 25) is reduced to Score (out of 5/10) as per the course requirement.
SHRI K.V.O. JAIN MAHAJAN - MUMBAI
SANCHALIT
NAVNEET) CHARITABLE HOSPITAL & PRINCE DIAGNOSTIC CENTRE
jos
Regd No.: E26713 CONDUCTED BY: SHRI K.V.O, JAIN MANAV SEVA KENDRA, DAHISAR Regd. No. E-17051
Reliable Residency, Near Achole Talav, Achole Road, Nallasopara (E), Dist. Palghar. Tel.:77097 22247 /
1st Fleer Chandra Dashan Bldg. Behind Jain TeFmple, Aear Railway Station, 77097 31116/ 77097 77351
Lab. No 2475
Nallasopara (E), Dist. Palghar. Tel. 91376 30280
Date 03/Jur2024
Patient Name: 94771
Age/Gender :18 Years/F
Reffered By : OPD Sample Date : 03/Jun/2024 11:02
Test Name Result Unit Normal Range
C.B.C. ESR
HAEMOGLOBIN% 10.6 gms/dl 11.5 - 16.5 gms/dl
RED BLOOD CELLS 4.47
*10*6/ul 3.90 - 5.60 *10*6/ul
PACKED CELL VOLUME 34.8 35.0- 60.0 %
MEAN CORPUSCULAR VOLUME 77.85 fl 76.00 - 97.00 fl
MEAN CORPUSCULAR HB 23.71 Picograms 25.00- 31.00 Picograms
MEAN CORPUSCULAR HB CONC 30.46 % 33.00 - 37.00 %
PLATELET COUNT 269
*I0^3/ut150450 10^3/ul
R.D.W. 15.5 % 11.5 - 16.5 %
TOTAL W.B.C. COUNT 5700 /cmm 4000 - 11000 /cmm
DIFFERENTIAL COUNT
NEUTROPHILS 54 40- 75 %
LYMPHOCYTES 38 20 - 45 %
MONOCYTES 06 1.00 - 10.00 %
EOSINOPHILS 02 1.00- 6.00 %
BASOPHILS 00 0-1%
ABNORMALITIES OF W.B.C.s Nil
ABNORMALITIESOF R.B.C.s Hypo +, Micro +
Remark
ESR 2 mm 0 - 20 mm
Dr.Ameya Khadilkar Dr.Daxesh Patel
M.D. M.D.
Lab Techtician
Consultant Pathologist Consultant Pathologist
A Dataman Software (0512) 2376505,2317191 Printed On:03/Jun/2024 12:02
TATHOLOGICAL REPORT D COMPLETE BLOOD
COUNT(CB)
Fondion fsst xasponds4 to mloobial irteatiny, Hhey engult end dechey
batoia
lymphoute2o-4o %in wBc, welks to yeaus likespen):
Fondoh Key playes
Tcoly Atack nefeted
34
Monauta 2-87% in WBG, days to manth litespan)
Fontoniransfo ato mauophages or denctitie alle n tissues, cohe tRey
cnaut pothogand ondprzust antgunt to Tul
4.Eosinophils( 4% in WBe, 8-12 days lkspan)
Fundtion: ambat pastaiio infestons play a eoe n allegi dastiong
undaran FOR EDUCATIONAL USE
5.
Fndtion : Rlease histaine dueing allgt adird nflaMimattone
FUNCTTON OP RBGs
2 Remove Casebon coxidu : Toansport cO tooM tssuy back the dung
8. |Maintain Arid- base baane: Hele ugulote blood p by tranuporhng cosebon
ioxtde
buppst nthent deliey: Ad hcotla matabolism hy providing oxygn.
S Regulote blood yiscasthy : Contibutz to Hoad ftew h pseuure
Trangost nitic oxide: Help talax Bood vetele e Iapove chauletton
tUNCTION OF PLATE LETS
tempory plug t at af blood vesal
2 Wond heing: uy suleae grouth dator that premáte fssue sepair helng
3- |Nessel apuir:Platdt kelp in canatidion of blod veuel atn mjusy, suducing bleod
Indaram FOR EDUCATIONAL USE
5. Basphils (<l% InwBc, tew hau to kew da lfespan)
Funtion: Rlense histansine duxtng allengl atlons l înflaamatten
FUNCTION OF RBCs
1:
2 Remove Caschondosde Toanspsrt co, aom tissues back t the dunge
3.Mairtain Aid- base balane: Help nguledte blood pH by tranporting tarbon
dlioxide
Lsuppostt nstint dulvy: Aid malalan matabolism hy providing oxygan:
S. Requlate bood viseosty: Contibute to laed flow e paeure
6.Transpost nitie oside: Help salex Wood veseta ae Irmpake cinuldton
PUNCTION OF PLATE LETS
Blood elottng (H&mastais) :?latestt tomm a temporey plug ot t ot blood vead
RWhnd healing: They suleak outh tazto that poomÑt Hssue epair healing
3- Nestel epuir Platehs help in constiion of blood veres aten iniusy, duing blood
Sundaram) FOR EDUCATIONAL USE
YATHOLOGTCAL CONDITION:
White bood cals (wBGs)
eountwhi Can wolt om vira
tafedton chemotheHapy.
2-| Red bood
Anemia A coniton ahee thes ase nsuffiaert RBCs o henaglebin,
broale diseases genciie dsordeses.
Palyuthuniaz An aespadutton ot RGG, wbidh can cause
blood and incat the isk af bood clots. Tt can be
pimay (du to bohu mazos disoreoy) scanday (du to
Low oxygen leNels tumox
3 Plateltt
|Thombeeytsis An incaeage in plalet caunt which cah diad t abnoma
elotting and ineuee the sisk ot thrombesis Tt can be
ative (ds to tetion, infommation, o iron dtdeny)
lso keessential
thembouytenia
fundaram FOR EDUCATIONAL USE
Disseralnated Tntavasulan leggletton PI):A loncitio chusatudnad
by widaspad aattiag and sledirg, aden ulting a dapl
Sundara FOR EDUCATIONAL USE
Regd. No XXXX54826XX
G+9112345 67890
Labsmart Software M yourlabnamegsysibcom
Sample Letterhead # httpsl/www.yourlabgane in
1007
Registered on : 7/10/2024 05:32 PM
:22YRS IM
Aoe/Sex Collecled on : 7/10/2024
Relerred by :Dr. Sachin Patll (MBBS) : 7/1012024
Recelved on
Reg,no. :1007 Reported on : 7/10/2024 05:33 PM
BIOCHEMISTRY
LIPID PROFILE
VALUE UNIT AEFERENCE
TEST
TOTAL CHOLESTEROL 180 mg/dl 125- 200
172 mg/dl 25- 200
TRIGLYCERIDES
HDL CHOLESTEROL 55 mg/dl 35- 80
90.60 mg/dl 85- 130
LDL CHOLESTEROL
VLDL CHOLESTEROL 34.40 mg/dl 5- 40
1.65 1.5 -3.5
LDL/HDL
TOTAL CHOLESTEROL/ HDL 3.27 3.5 -5
TG/ HDL 3.13
NON-HDL CHOLESTEROL 125.00 ne,
Abnormallties of lipids are associated wlth Increased risk of coronary artery disease (CAD) in palients with DM. This risk can be
reduced by intenslve trealment of lipid abnormalities. The usual pattern ol lipid abnormalitles in type 2 DM is elevaled
triglycerides, decreased HDL cholesterol and higher proporion of small, dense LDL particles. Cholesterol is a lipid found in all
cell memnbranes and in blood plasma. It ls an essenlial cormponent of the cell membranes, and is necessary for synthesis of
sierold hormones, and for the formation of bile acids. Cholesterol is synthesized by the liver and marny other organs, and is also
ingested inthe dletl. Triglycerides are lipids in whlch thrae long-chain fatty acids are atached to glycerol. They are presant in
dietary lat and also synthesized by llver and adipose tissue.
Newer treatment goals and statin initlation thresholds based on the risk categories proposed by Lipid Assoclalion of India in
2020.
Risk Category Treatment Goal Consider Therapy
LDL'Cholesleroi {Non-HDLCholestero1;LDL cholesterol; Non HDL Cholesteroi
(LDL-C) (Mg/dl) (Non HDL-C) (Mg/dl) (LDL-C) (Mgldl) (Non HDL-C) (Mg/dl)
<50 {<80 ie80
Extreme Risk Group Calegory A,(Oplional Goale=30) (Optlonal Goal<=60) >=50
Extreme Risk Group CalegoryA<-30 i<e60 >30 i>60
Very High <50
High 70 f100 >70 100
ial
Mr. Seohin Sherma Dr. A. K. Asthøna
DMLT, Lab Incharge MBBS, MD Palhologist
NOT VALID FORMEDICO LEGAL PURPOSE
Work timings: Monday to Sunday, Bam to 8 pm
Please correlate olinlcolly. Although the tost rOsults arc chockod thoroughly, In cos$e of ony unexpected (est results which
could bo due to machlna orror or typing error or ony other roason ploasa contoct tholob Immediotoly for a frae evaluotian.
ATHOLCGICAL REPORT OF LIPID PROFTLE
LOw-DENSITY LIPOPROTEIN (LD)
k s a dype of lipopotin Hht playea cudal euglk in pid
metaboRsm and th trnport af cholesteal witin the body
fNCTIONS
|Cha lestexel transport tto caldi
calli IDL Aliva chokstesl to cellh thoughat he
bely whee tis used foy Vasious tunctong, Auch aa bilding call membxanes,
prodrung euoid homones ond aynthesízing tmin D.
LDL deiveg
9Eaesytg
Atoxed nd sed as n
chelestesol ond lipid to celle whste con be
whenneded.
3.
Membran omatien chalestesal coded by LDL is wittcal fox maánstedni ng
the inteqity and Auidity of ell. naembzanet
4.eid homone prodaion : 1DL deli ves choltteAal to endacaine alanda f a
Aynthesis ot stenaBd homonel, such ed cortis l, estrogn, testostekane anl
aldestecane
5.
&uppot cfx NeeMoUS system un dion Chalesteal delveed by LDL Ja esLoial
x he toomation and the mainta'nana cf myelin, which insolte
Abre and cidy in efiient sgnal transmnission ih the nesous Bystam.
undaram FOR EDUCATIONAL USE
HTH-DENSITY LIpOPRO TETHI(HDL)
to es aood chalsttauc' playe en
estetialole ih maintiningpid honuostask and ceslovaB udas hatth
FUNGTIONS.
Revese cholestol transpost HDl caleets excese choluteol trom pephsa
Ssuey cnd tsanspexta it back to Lven tor exuton ox convcsion ro bila
adds This prous helpsprvut holesteol bultd up in the blood stsm
(asdiovaua protion' HDL heles weluce the sk of etheosletosis by
umouing chalestol ctrem tuid walls, ducing plaqu dormatian &
premoting huat health
Anrh- inttam matony popesties HDL Posscsxes ont inttammaton ttets by
hutralzing po nlammotoy substhuy cnd sudeing eridatve stres,which
contiibute to vasua damage
Ari oxidant tuntion> HDLprvnts the oxidatíon af DL cholesteol, a key step in
the fomotion ot atheosaaie plaqueke
5. Endotkalial nton inmprovenent : HDL Appoxta the rnaintinane end uepoir
6 Lipld Radistabutioni HDL poticyatea inedistibuting ipida between pa
pxotcins s wildor munbrane, en auring prepeu ipld metaballsro and balane.
ram) FOR EDUCATIONAL USE
VERY LOw-DENSITY LIPOPROTEIN(VLDL)
FUNGTIONS
sythsied in
he ivex, to pepheal tissue poide enuqy
2Delivey a cholesteels while t VLDL pimaslly cazsie tiglywdla, H also
tonspoxk cholestoul to tissueA cfar yas funtons, such as eld mambrona
Ayntheis & homane producien.
Oxidzd cor enegypatiuloly duzing ts ing phyalcal atity
LDL fomaton Aften VLDL deioy toiglyaeides to tissug,
ipopratein CD) aad ewentually Aawcn síty ipopretujn (LDy, which ontinaes
pid Homzostais s VLDL playa C
gld lavc in thu blaodstream by egulating tigyuzdde dstabution
undaram FOR EDUCATIONAL USE
DRUGrS USED TO TREAT HYaRLIPIDEMTA.
HMG CoA ledutasA Saibitos (Stottn: Atrvatetin Aimyastatin
Nonctatiy
Bile acid scqussandts- (holesthyyamine , Colesevelam
Niothic_aid Niain
Fibyotes- fenabrde
Nen phaoacolagice counedliz o bgedecie
ietsy Modiicatiens
Beduce settal tets: limit isteke ot sed meat, tull fat da'sy, cenel
procesed toode.
Avoid Frons fauto: Chack dobey for hysaguntd oile in pewsed foods
vegtables n your dit
ansume heathy es: Emphaize omega - 3- dety aide from sourus ihe
aty Hsh Aaxsede e walnuti Ue olik oll ihstead ot butteo mesgadne.
PLiit Dictasy chaleteal? Found h egg yolke, agan meats, and dhelesha
undaram) FOR EDUCATIONAL USE
Toespt pet enale Jnole: fownd n fortkd toodhe megos¥n,
oYenge juie ond yaghust
2 alReglax Phytlcad Atity
Aobi eKenisei Aim for t oast 3o rminuty ot modute-intnsity
brniK (wal ling. egging iuimming yeing on mmest dey
ent Taiaing: Thdud suiskana erotisy at leat to days a weuk
to enhona metabolie heath.
Achesred tHaictgina hthy wyt
wciqat s-lo°2) ten algniticenly lowen iDL eholestesl & tiglyuida.
4`moking Ceiaion
Pradiina dmskiy cestctinn Aawess Hhe LDl evele,Anme king
Lous HDL (good chslestes) end demage blood vegels. Prouide
stategies and eloUYLS foy quithng scking
A
Poachu 3lexotion teehniqAus ik medittim, yoga ox dqp heath íng
to menage sty, which con hyatty ipat ipid Aeva
FOR EDUCATIONAL USE
aram
daram)
*Keoenes
Fducate
Montax 1 G
Robbins *el AGxcs Liait
meycine
OHO wlwcomwi
Hemetology: petonelzed
helistic
goal (1dink]day
(2-2)
menituring alcohal Aloho)
uicll'ny BasicCotaen tor
con Consu
for pánúpla path Enourag men,
ise nption
maenagumet logie
LUSE
FOR k 2
tiglyides.
dinksday
pratlu Basie
xgula
ot (1th ot
dyslipicemla for En
eolDiscax
) caurage
ipid men)
Coth pofill
ta modxaton
alalts. c)
cheehe