Msds Vk-Wsa Catalyst
Msds Vk-Wsa Catalyst
2011
Date of last issue: 19.12.2022
Revision Date: 15.11.2023
Version: 2.13 Page 1 of 15
VK-WSA
1.2 Relevant identified uses of the substance or mixture and uses advised against
○ Identified uses: Sulphuric acid catalyst.
For the full text of the H-Statements mentioned in this Section, see Section 16.
○ Hazard pictograms
○ Hazard statements
- H318: Causes serious eye damage.
- H331: Toxic if inhaled.
- H341: Suspected of causing genetic defects.
- H350: May cause cancer.
- H361fd: Suspected of damaging fertility. Suspected of damaging the unborn child.
- H362: May cause harm to breast-fed children.
- H373: May cause damage to organs (Lungs, Respiratory Tract) through prolonged or
repeated exposure if inhaled.
- H412: Harmful to aquatic life with long lasting effects.
○ Precautionary statements
- P201: Obtain special instructions before use.
- P260: Do not breathe dust.
- P280: Wear protective gloves/ protective clothing/ eye protection/ face protection.
- P304 + P340 + IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call
P311: a POISON CENTER/ doctor.
- P305 + P351 + IF IN EYES: Rinse cautiously with water for several minutes. Remove contact
P338 + P310: lenses, if present and easy to do. Continue rinsing. Immediately call a POISON
CENTER/ doctor.
- P308 + P313: IF exposed or concerned: Get medical advice/ attention.
- P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
3.2 Mixture
REACH Registration
Components Classification %w/w
Number
Amorphous Silica 01-2119379499-16- not to be classified 60 - 70
CAS-No.: 7631-86-9 XXXX
EC-No.: 231-545-4
Potassium sulphate 01-2119489441-34- not to be classified 10 - 30
CAS-No.: 7778-80-5 XXXX
EC-No.: 231-915-5
Aluminum sulfate 01-2119531538-36- Eye Dam. 1; H318 5 - 10
CAS-No.: 10043-01-3 XXXX Met. Corr. 1; H290
EC-No.: 233-135-0
Divanadium pentoxide 01-2119531331-54- Acute Tox. 3; H301 5-9
CAS-No.: 1314-62-1 XXXX Acute Tox. 2; H330
EC-No.: 215-239-8 Eye Dam. 1; H318
Muta. 2; H341
Carc. 1B; H350
Repr. 2; H361fd
Lact. H362
STOT SE 3; H335
STOT RE 1; H372
Aquatic Chronic 2; H411
Sodium sulphate 01-2119519226-43- not to be classified 1-7
CAS-No.: 7757-82-6 XXXX
EC-No.: 231-820-9
No crystalline silica forms found.
For the full text of the H-Statements mentioned in this Section, see Section 16.
4.2 Most important symptoms and effects, both acute and delayed
○ Inhalation: Toxic by inhalation. May cause damage to organs through prolonged or
repeated exposure if inhaled. Inhalation of excessive amounts of dust may
cause irritation of the respiratory system; symptoms may include coughing
and difficulty in breathing.
○ Skin contact: May cause skin irritation.
4.3 Indication of any immediate medical attention and special treatment needed
○ Symptoms: None known.
Further information
Prevent fire extinguishing water from contaminating surface water or the ground water system.
Fire residues and contaminated fire extinguishing water must be disposed of in accordance with local
regulations.
Additional exposure limits for substance(s) that may be released during handling
DNEL /PNEC
Amorphous Silica(7631-86-9)
Workers: DNEL: - No data available
Environment: PNEC: No data available
Potassium sulphate(7778-80-5)
Workers: DNEL: - No data available
Environment: PNEC: No data available
Divanadium pentoxide(1314-62-1)
Workers: DNEL: - No data available
Environment: PNEC: No data available
Sodium sulphate(7757-82-6)
Workers: DNEL: - No data available
Environment: PNEC: No data available
10.1 Reactivity
Stable under normal conditions.
○ Ingestion: Ingestion may cause irritation of the mouth and throat and may cause
discomfort.
○ Long term effects: Substances which should be regarded as if they are carcinogenic to
man. Substances which cause concern for man owing to possible
mutagenic effects but for which the available information is not
adequate for making a satisfactory assessment. Suspected of
causing genetic defects. Possible risk of irreversible effects.
Substances which cause concern for human fertility. Substances
which cause concern for humans owing to possible developmental
toxic effects. Prolonged or repeated inhalation may cause damage to
the lungs. Vanadium pentoxide is in EU classified as a mutagenic
substance in category 3 i.e. may cause possible risk of irreversible
effects. Vanadium pentoxide is also in EU classified as toxic for
reproduction in category 3, i.e. possible risk of harm to the unborn
child. IARC: (International Agency for Research on Cancer) Group
2B: Possibly carcinogenic to humans
Acute toxicity
Assessment: Toxic if inhaled.
» Oral
Amorphous Silica: LD50 Oral(Rat): > 5.000 mg/kg
Method: OECD Test Guideline 401
Potassium sulphate: LD50(Rat): > 2.000 mg/kg
Method: OECD Test Guideline 425
Aluminum sulfate: LD50(Rat): > 2.000 mg/kg
Method: OECD Test Guideline 401
Divanadium pentoxide: LD50(Rat): 221,1 mg/kg
Method: OECD Test Guideline 401
Sodium sulphate: LD50(Rat): > 2.000 mg/kg
Method: OECD Test Guideline 423
Mixture: Acute toxicity estimate: 2.785 mg/kg
Method: Calculation method
Remarks: Not classified due to data which are conclusive although
insufficient for classification.
» Dermal
Amorphous Silica: LD50 Dermal(Rabbit): > 2.000 mg/kg
Potassium sulphate: LD50 Dermal(Rat): > 2.000 mg/kg
Aluminum sulfate: LD50(Rat): > 5.000 mg/kg
Method: OECD Test Guideline 402
Divanadium pentoxide: LD50 Dermal(Rat): > 2.500 mg/kg
Method: OECD Test Guideline 402
Remarks: No adverse effect has been observed in acute toxicity tests.
» Inhalation
Amorphous Silica: LC0(Rat, 4 h): > 2,08 mg/l
Method: OECD Test Guideline 403
Potassium sulphate: LC0(Rat, 4 h): 3,6 mg/m³
Skin corrosion/irritation
Assessment: Not classified based on available information.
Amorphous Silica: Result: No skin irritation
Species: Rabbit
Exposure time: 4 h
Method: OECD Test Guideline 404
Aluminum sulfate: Result: No skin irritation
Species: Rabbit
Exposure time: 4 h
Method: OECD Test Guideline 404
Divanadium pentoxide: Result: No skin irritation
Species: reconstructed human epidermis (RhE)
Method: Regulation (EC) No. 440/2008, Annex, B.46
Respiratory sensitisation
Assessment: Not classified based on available information.
Amorphous Silica: Exposure routes: Inhalation
Remarks: study scientifically unjustified
Divanadium pentoxide: Exposure routes: Inhalation
Remarks: Not classified due to lack of data.
Skin sensitisation
Assessment: Not classified based on available information.
Amorphous Silica: Exposure routes: Dermal
Remarks: study scientifically unjustified
Divanadium pentoxide: Exposure routes: Dermal
Test Type: Maximisation Test
Species: Guinea pig
Result: negative
Method: OECD Test Guideline 406
Carcinogenicity
Assessment: May cause cancer.
Amorphous Silica: No observed adverse effect level: 1.800 - 3.000 mg/kg bw/day
Application Route: Oral
Species: Rat
Result: negative
Reproductive toxicity
Assessment: Suspected of damaging fertility. Suspected of damaging the unborn
child. May cause harm to breast-fed children.
Amorphous Silica: Reproductive Toxicity/Fertility
This information is not available.
Reproductive Toxicity/Development/Teratogenicity
Result: No adverse effects
Test Type: reproductive and developmental toxicity study
Species: Rat
Application Route: Oral
Divanadium pentoxide: Reproductive Toxicity/Fertility
LOAEL: 4 mg/m3
Test Type: Fertility
Species: Rat
Application Route: Inhalation
Symptoms: Effect on estrous cycle
NOAEL: 15 mg/kg bw/day
Test Type: Multi-generation study
Species: Rat
Application Route: Oral
Symptoms: Effects on mating performance, Effects on fertility, Effects
on reproduction parameters
Reproductive Toxicity/Development/Teratogenicity
NOAEL: 7,41 mg/kg bw/day
Species: Mouse
Symptoms: Effects on foetal development
Remarks: Read-across (Analogy)
Aspiration hazard
Assessment: Not classified based on available information.
12.1 Toxicity
Harmful to aquatic life with long lasting effects.
» Acute toxicity
No information available.
» Chronic toxicity
No information available.
» Other organisms relevant to the environment
No information available.
14.2 UN proper shipping name: Toxic solid, inorganic, n.o.s. (Divanadium pentoxide)
14.6 Special precautions for user: No special precautions are needed in handling this material.
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
○ Take note of Dir 94/33/EC on the protection of young people at work.
○ Take note of Dir 92/85/EEC on the safety and health at work of pregnant workers.
Key or legend to abbreviations and acronyms used in the safety data sheet
○ DNEL Derived No Effect Level
○ PNEC Predicted No Effect Concentration
○ Acute Tox. Acute toxicity
○ Aquatic Chronic Long-term (chronic) aquatic hazard
○ Carc. Carcinogenicity
○ EH40 EH40/2005 Workplace exposure limits
○ Eye Dam. Serious eye damage
○ Lact. Effects on or via lactation
○ Met. Corr. Corrosive to metals
○ Muta. Germ cell mutagenicity
○ Repr. Reproductive toxicity
○ STOT RE Specific target organ toxicity - repeated exposure
○ STOT SE Specific target organ toxicity - single exposure
○ TWA Long-term exposure limit
Classification and procedure used to derive the classification for mixtures according to
Regulation (EC) No. 1272/2008:
Training advice
Provide adequate information, instruction and training for operators.
The above information is believed to be accurate and is based on our present state of knowledge and experience. However, no
warranty or representation with respect to such information is intended or given. This information is intended to be used for
safety and environmental purposes only and should not be relied upon for any other purposes.
Information contained herein is confidential; it may not be used for any purpose other than for which it has been issued, and may
not be used by or disclosed to third parties without written approval of Topsoe A/S.