Exp. No.

1 Date:
Aim: To prepare and submit 30 ml of Simple Syrup IP.

Reference:
1. Mehta R.M., Dispensing Pharmacy, Vallabh Prakashan, New Delhi, 2017; 155 – 156.
Requirements:
Apparatus Required:
Mortar & pestle, weigh balance, measuring cylinder, glass rod, spatula, beaker, stirrer etc.
Chemical Required:
Sucrose and purified water.
Principle:
Syrups are sweetened, viscous, concentrated solutions of sucrose or other sugars in water or anyother
suitable aqueous vehicles. These are further classified into 2 classes.
1. Simple flavored syrups
2. Medicated syrups
Simple flavor syrups:
Do not contain any medicament or drug. These syrups are used as a vehicle for other Liquid
preparation to mask the disagreeable taste of drug.
Medicated syrups:
These contain some medicinal substance along with their other additives. Sucrose concentration in
simple syrup is a 66.7 %w/w.
Formula:

Sl. No. Ingredients Official formula Requiredquantities

1 Sucrose 667gm
2 Purified water, quantity 1000ml 30ml
sufficient to produce (q. s)

Calculations:

Procedure:
Add water to sucrose in a beaker and heat on water bath until sucrose dissolves add sufficient boiling
water to produce the final volume. Filter hot syrup through cotton wool. cool the syrup and
preservatives may be added for stability. Add more purified water to make up the required volume.
Filter and transfer in a suitable container.
Category:
Sweetening agent, vehicle
Use:
Simple Syrups are used as vehicles for drugs such as antibiotics, Antihistaminic, antitussives and
vitamins.

Storage:
Stored in a well closed container at a temperature not exceeding 250C.
Label:
 SIMPLE SYRUP IP
30ml
Composition:
Sucrose BATCH NO. MFG. DATE:
Purified water
MFG. LIC. NO.: EXPIRY DATE:
Category: Sweetening agent, vehicle

FOR INTERNAL USE ONLY.

Use: Simple Syrups are used as vehicles for drugs such as antibiotics, Antihistaminic, antitussives
and vitamins.
Storage: Stored in a well closed container dark in a cool place and temperature not exceeding 250C
MFG. BY: ABCD Batch: Roll No.:

Report:
 Exp. No. 2 Date:
Aim: To prepare and submit 20ml of Piperazine citrate elixir.
Reference:
Mehta R.M., Dispensing Pharmacy, Vallabh Prakashan, New Delhi, 2017; 158 - 160
Requirements:
Apparatus Required:
Mortar & pestle, weigh balance, measuring cylinder, glass rod, spatula, beaker etc.
Chemical Required:
Piperazine citrate, chloroform spirit, glycerin, orange oil, syrup, purified water.
Principle:
Piperazine Citrate Elixir is mainly an anthelmintic. This kind of drug works to paralyze parasites that
may invade the host body and cause diseases. It therefore helps to remove the parasites andthus
inhibit the spread of disease in the body. The medicine is used totreat
ascariasis, enterobiasis, also called common pinworms. The drug immobilizes the parasitic worms
first, which are later passed out of the body through stool. This drug can only be obtained with a
proper prescription by your doctor and is not available over the counter. The medicine is available in
the form a tablet or as syrup.

Formula:

Sl. No. Ingredients Official Required

Formula quantities
1 Piperazine citrate 180gm
2 Chloroform spirit 0.5ml
3 Glycerine 100ml
4 Orange oil 0.25ml
5 Syrup 500ml
6 Purified water 1000ml 20ml

Calculation:

Procedure:
Dissolve piperazine citrate in part of water. Then mix with agitation orange oil, glycerin, syrup in
chloroform spirit and pour in watery solution of piperazine citrate. Adjust the volume with
sufficient purified water. Filter and transfer in a suitable container.

Storage:
Stored in a well closed container at a temperature not exceeding 250C.

Use:
It is used as anthelmintic which is used in the treatment of worm infections.
Label:

PIPERAZINE CITRATE ELIXIR

20ml
Composition:
Piperazine citrate
Chloroform spirit BATCH NO. MFG. DATE:

Glycerin
MFG. LIC. NO.: EXPIRY DATE:
Orange oil
Syrup
Purified water
Category: Anthelmintic
FOR INTERNAL USE ONLY.
Use: It is used as an anti-helminthics are used in the treatment of worm infections.

Storage: Stored in a well closed container dark in a cool place and temperature not exceeding
250C

MFG BY: ABCD Batch: Roll No.:

Report
 Exp. No. 3 Date:
Aim: To prepare and submit 30ml of aqueous iodine solution.
Reference:
Gupta A.K., Jain V.K., Pharmaceutics-I Practical Note Book, CBS Publishers & Distributors
[Link].2020; 15
Requirements:
Apparatus Required:
Mortar & pestle, weigh balance, measuring cylinder, glass rod, spatula, beaker, funnel etc.
Chemical Required:
Iodine, potassium iodide and purified water
Principle:
In pharmaceutical practice solution are defined as liquid preparation containing one or morechemical
substances usually dissolved in water. Aqueous iodine solution is also known as Lugol’s Solution
and contain 5%w/v of iodine and 10% w/v of potassium iodide.

Formula:

Sl. No. Ingredients Official formula Working formula Required quantities

1 Iodine 50gm

2 Potassium iodide 100gm

3 Purified water 1000ml 30ml

Calculation:

Procedure:
Dissolve potassium iodide and iodine in a purified water. Shake well till it dissolve. Then add
sufficient purified water to make up the required volume. Filter and transfer in a suitable container.

Use: Antiseptic

Storage: Well closed container made up of iodine resistant material.

Dose: 0.3 to 2ml.

Label:

AQUEOUS IODINE SOLUTION

30ml
Composition:
Iodine
BATCH NO.: MFG. DATE:
Potassium iodide
Purified water
MFG. LIC NO.: EXPIRY DATE:
Category: Antiseptic

FOR EXTERNAL USE ONLY

Use: It is used as an antiseptic
Storage: Stored in a well closed container at a temperature not exceeding 250C
MFG BY: ABCD Batch: Roll No.:

Report:
 Exp. No.-4 Date:
Aim: To prepare and submit 30ml of Castor oil emulsion.
Reference:
1. Mehta R.M., Dispensing Pharmacy, Vallabh Prakashan, New Delhi,2017;217
Requirements:
Apparatus Required:
Mortar & pestle, weigh balance, measuring cylinder, glass rod, spatula, beaker, funnel etc.
Chemical Required: Castor oil and Cinnamon water q. s.
Principle:
An emulsion is a mixture of two or more liquids that are normally immiscible (unmixable or
unblendable) owing to liquid-liquid phase separation. Depending upon the nature of the dispersed
phase, the emulsions are classified as (i) Water-in-oil emulsion (W/O) (ii) oil in water emulsion (O/W)
Liquid paraffin is primarily used as a pediatric laxative in medicine and is a populartreatment
for constipation and encopresis. Castor oil emulsion is used as a laxative, to empty the GI tract, while
the patients is prepared for thecolon X –ray, proctoscopy and endoscopic examination.

Formula:

Sl. Ingredients Official Working formula Required

No. formula quantities

1 Castor oil 20ml

2 Cinnamon water q. 50ml 25ml

s.

Calculation:
Procedure:
 Weigh calculated quantity of acacia is take in a mortar.
 Measured quantity of cinnamon water at once (calculated for primary emulsion formula) is added
into the mortar.
 The content, in the mortar is triturated to form mucilage.
 Measured quantity of castor oil is added in small quantities, with constant, rapid and light trituration
to produce a thick cream. Trituration is continued for three minutes to obtain a white stable emulsion.
It is indicated by click sound.
 Some more quantity of cinnamon water is added gradually with continuous trituration.
 The contents are transferred into a measuring cylinder.
 The pestle and mortar are rinsed with cinnamon water and rinsing are transferred into the measuring
cylinder.
 The quantity is adjusted to the required volume using cinnamon water and the contents are stirred
well.
 The castor oil emulsion is then transferred into a wide mouthed light resistant container.
 The bottle is capped, labelled, polished and submitted.
 Use: Castor oil emulsion is used as a laxative, to empty the GI tract, while the patients is preparedfor
the colon X –ray, protoscopy and endoscopic examination.

Storage: It should be store in a tightly –closed container in a cool place.

Category: Laxative.
Dose: 4 -6 ml
Direction: Take on an empty stomach followed with one full glass of water.

Label:

CASTOR OIL EMULSION

25ml
Composition:
Castor oil BATCH NO. MFG. DATE:
Cinnamon water q.s
MFG. LIC. NO.: EXPIRY DATE:

Category: Laxative

FOR INTERNAL USE ONLY.

Use: Castor oil emulsion is used as a laxative, to empty the GI tract, while the patients are prepared
for the colon X –ray, protoscopy and endoscopic examination.

Storage: It should be store in a tightly –closed container in a cool place.

MFG BY: ABCD Batch: Roll No.:

Report:
Exp. No.-5 Date:
Aim: To prepare and submit 30ml of Cod Liver Oil emulsion.
Reference:
Mehta R.M., Dispensing Pharmacy, Vallabh Prakashan, New Delhi, 2017;217
Requirements:
Apparatus Required:
Mortar & pestle, weigh balance, measuring cylinder, glass rod, spatula, beaker, funnel etc.
Chemical Required: Cod liver oil, Egg yolk, Purified water q.s
Principle:
An emulsion is a mixture of two or more liquids that are normally immiscible (unmixable or
unblendable) owing to liquid-liquid phase separation. Depending upon the nature of the dispersed
phase, the emulsions are classified as (i) Water-in-oil emulsion (W/O) (ii) oil in water emulsion (O/W).
Cod liver oil is a rich sources of vitamin D and therefore used as an anti-rachitic agent.

Formula:

Sl. Ingredients Official Working formula Required

No. formula quantities

1 Cod liver oil 30ml

2 Egg yolk 4ml
Purified
3 water q.s 60ml 30ml

Calculation:

Procedure:
 Egg yolk is separated from the broken egg and placed in a measure. Equal volume of wateris added
and mixed thoroughly.
 The calculated volume of the above egg yolk is placed in a mortar.
 The calculated volume of cod liver oil is added to the mortar and mixed with constantstirring.
 Purified water (1/3rd the total quantity0 is gradually added with constant trituration.
 The mixture is strained through a muslin cloth.
 Mortar and pestle are rinsed with little volume of water and transferred through the muslin cloth.
 The volume is adjusted to the required level with water in a measuring cylinder.
 The contents are mixed well and transferred into a narrow-mouthed container
 The container is capped, polished, labelled and dispensed.

Use: It is used as an Anti-rachitic agent (in deficiency of vitamin D).

Storage: It should be store in a tightly well closed container in a cool place.
Category: Anti-rachitic (in deficiency of vitamin D)
Dose: Not more than 10ml daily.
 Label:

COD LIVER OIL EMULSION

30ML
Composition:
Cod liver oil BATCH NO. MFG. DATE:
Egg yolk
MFG. LIC. NO.: EXPIRY DATE:
Purified water q. s
Category: Anti-rachitic (in deficiency of
vitamin D)
FOR INTERNAL USE ONLY
Use: It is used as an Anti-rachitic agent (in deficiency of vitamin D)

Storage: It should be store in a tightly well closed container in a cool place.

MFG BY: ABCD Batch: Roll No.:

Report:
 Exp. No.-6 Date:
Aim: To prepare and submit 30ml of Calamine lotion.
Reference:
Mehta R.M., Dispensing Pharmacy, Vallabh Prakashan, New Delhi, 2017; 165 -166
Requirements:
Apparatus Required:
Mortar & pestle, weigh balance, measuring cylinder, glass rod, spatula, beaker, funnel etc.
Chemical Required:
Calamine, Zinc oxide, Bentonite, Glycerin, sodium citrate, Liquefied phenol, rose water,
Purified water.
Principle:
It is a suspension containing in-diffusible Solids for external use. Here we use bentonite as a
suspending agent, dispersion of bentonite is observed if it is mixed intimately with insoluble
medicament i.e. calamine. Zinc oxide used here acts as astringent & protective agent. Sodium citrate
causes partial deflocculation of calamine and transfers bentonite from gel to solid form in its absence.
Hence it is thicker & difficult to pour from bottle.

Formula:

Sl. No. Ingredients Official Working formula Required quantities

formula
1 Calamine 150gm
2 Zinc oxide 50gm
3 Bentonite 15gm
4 Glycerine 5ml
5 Sodium citrate 5ml
6 Liquefied phenol 50ml
7 Rose water 1000ml 30ml

Calculation:

Procedure:
 Mix the weighed amounts of Calamine, ZnO, Bentonite in a mortar & pestle.
 Triturate with a solution of sodium citrate in 5 ml of water.
 Add required amounts of liquefied phenol & Glycerine.
 Mix well, to this add more of vehicle to produce required volume, mix thoroughly so as to get
uniform preparation. Filter and transfer in a suitable container.
Directions:
Shake well before use. To be applied 2-3 times a day.
Uses:
 This is used as astringent.
 Used as smoothening agent and gives relief from itching and pain during skin diseases and
infections.
 It is also used in ring worm infections.

Storage: Stored in a well closed container dark in a cool place at a temperature not exceeding250C.
Label:
CALAMINE LOTION
30ml
Composition:
Calamine
Zinc oxide BATCH NO. MFG. DATE:
Bentonite
Glycerine
Sodium citrate MFG. LIC. NO.: EXPIRY DATE:
Liquefied phenol
Rose water
Category: Astringent
FOR EXTERNAL USE ONLY
Use: This is used as astringent
Storage: Stored in a well closed container dark in a cool place and temperature not exceeding 250C
MFG BY: ABCD Batch: Roll No.:

Report:
 Exp. No.-7 Date:
Aim: To prepare and submit 20ml of Magnesium Hydroxide mixture.

Reference:
 Mehta R.M., Dispensing Pharmacy, Vallabh Prakashan, New Delhi, 2017; 150-151.
 Subrahmanyam C.V.S., Thimmasetty J.J, Prabhushankar G.L., Laboratory manual of Pharmaceutics.
Vallabh Publication, Delhi, 2019; 47-48.
Requirements:
Apparatus Required:
Mortar & pestle, weigh balance, measuring cylinder, glass rod, spatula, beaker, funnel etc.
Chemical Required:
Magnesium sulphate, sodium hydroxide, light magnesium oxide and purified water.
Principle:
It is aqueous of colloidal dispersion of magnesium hydroxide. It is prepared by precipitation method
and hydration method or both. It is not excessively thick or thin but holds design viscosity, it has two
actions in low dose (1 -4ml) it acts as an antacid, while in higher dose (8–10ml) it acts as a laxative.
Reaction:
MgO +H2O ------- Mg (OH)2 Mg SO4+ 2NaOH --------------------------Mg (OH)2 + Na2SO4

Formula:

Sl. Ingredients Official formula Working Required quantities

No. formula
1 Magnesium sulfate 47.5gm
2 Sodium hydroxide 50.5gm
3 Light magnesium 15gm
oxide
4 Purified water 1000ml 20ml

Calculation:

Procedure:
 Dissolve sodium hydroxide in sufficient purified water contained in a beaker.
 Triturate Magnesium oxide in a mortar with the solution of hydroxide to from a
smoothcream.
 Dissolve magnesium sulphate in sufficient water in a separate beaker.
 Add cream to the solution of magnesium sulphate with constant stirring. This mixture is
setaside for 48 hrs.
 After 48 hrs pour off the supernatant liquid.
 Add hot purified water to the precipitate of magnesium hydroxide to wash the sulphate
 ionsfrom precipitate.
 Transfer the washed precipitate to the suitable container and label it.
Dose: 1 to 4ml as antacid, 8 to 10ml as laxative.
Storage: Stored in an air tight container in a cool place.
Direction: Shake well before use
Label:
MAGNESIUM HYDROXIDE MIXTURE
20ml
Composition:
Magnesium sulfate BATCH NO. MFG. DATE:
Sodium hydroxide
Light magnesium oxide MFG. LIC. NO.: EXPIRY DATE:
Purified water
Category: Laxative.
FOR INTERNAL USE ONLY
Use: Laxative & Antacid
Storage: Stored in a well closed container dark in a cool place and temperature not exceeding 250C
MFG BY: ABCD Batch: Roll No.:

Report:
 Exp. No.-8 Date:
Aim: To prepare and submit 100gm of Simple ointment.
Reference:
 Mehta R.M., Dispensing Pharmacy, Vallabh Prakashan, New Delhi, 2017;238
 Pharmacopoeia of India.
Requirements:
Apparatus Required:
Mortar & pestle, weigh balance, measuring cylinder, glass rod, spatula, beaker, ointments slab etc.
Chemical Required:
Wool fat, hard paraffin, white soft paraffin, cetostearyl alcohol.
Principle:
Ointments are semisolid preparation meant for external application to the skin or mucous membrane.
They usually contain medicament or medicaments which are dissolved or dispensed or suspended or
emulsified as an antiseptic, antifungal agent.
Formula:
Sl. No. Ingredients Official Working Required
formula formula quantities
1 Wool fat 5gm
2 Hard paraffin 5gm
3 Cetostearyl 5gm
alcohol
4 White soft 85gm
paraffin

Calculations:

Procedure:
 Melt hard paraffin and Cetostearyl alcohol on water bath.
 To this incorporate wool fat and white soft paraffin.
 Stir until all ingredients are melted.
 Examine the contents for any foreign particles. Decant or strain if required.
 Stir the mixture thoroughly until cold.
 Pack it in an ointment jar, label, and dispense.
Direction: Apply as directed.
Use: This are used to treat seborrheic dermatitis and scabies.
Storage: Keep in well closed container and cool place.
Label:

SIMPLE OINTMENT
100gm

Compositions:
Wool fat BATCH NO. MFG. DATE:
Hard paraffin
Cetostearyl alcohol
MFG. LIC. NO.: EXPIRY DATE:
White soft paraffin
Category: Acne

FOR EXTERNAL USE ONLY.

Use: This are used to treat acne and also used to treat seborrheic dermatitis and scabies.

Storage: Stored in a well closed container dark and cool place and temperature not exceeding 250C

MFG BY: Batch: Roll No.:

Report:
 Exp. No.-9 Date:
Aim: To prepare and submit 100gm of Sulphur ointment I.P.
Reference:
 Mehta R.M., Dispensing Pharmacy, Vallabh Prakashan, New Delhi,2017;238
 Pharmacopoeia of India.
Requirements:
Apparatus Required:
Mortar & pestle, weigh balance, measuring cylinder, glass rod, spatula, beaker, ointments slab etc.
Chemical Required:
Sublimed Sulphur, wool fat, hard paraffin, white soft paraffin, Cetostearyl alcohol.
Principle:
Ointments are semisolid preparation meant for external application to the skin or mucous membrane.
They usually contain medicament or medicaments which are dissolved or dispensed or suspended or
emulsified as an antiseptic, antifungal agents and Sulphur ointment used to treat different skin
infections.
Formula:
Preparation of simple ointment base:
Sl. No. Ingredients Official formula Working formula Required
quantities
1 Wool fat 5gm
2 Hard paraffin 5gm
3 Cetostearyl alcohol 5gm
4 White soft paraffin 85gm 100gm

Sl. No. Ingredients Official formula Working Required quantities

formula

1 Sublimed 10gm
Sulphur
2 Simple ointment 90gm 100gm

Calculation:

Procedure:
Preparation of simple ointment:
 Required quantity of hard paraffin and Cetostearyl alcohol.
 Wool fat and white soft paraffin were incorporated and stirred until all ingredients weremelted.
 The mixture was stirred thoroughly until cooled.
Preparation of Sulphur ointment:
Sublimed Sulphur was triturated and finely shifted through sieve no.85. Required quantity of Sulphur
was taken on ointment base and mix small amount of ointment of simple ointment was gradually added
until homogeneous mass was obtained.
 Direction: Apply as directed.

Use:
 This are used to treat acne Sulfur ointment.
 This are used to treat seborrheric dermatitis and scabies.

Storage: Keep in well closed container and cool place.

SULPHUR OINTMENT I.P

100gm

Compositions:
Wool fat BATCH NO. MFG. DATE:
Hard paraffin
Cetostearyl alcohol
White soft paraffin MFG. LIC. NO.: EXPIRY DATE:
Category: Acne

FOR EXTERNAL USE ONLY.

Use: This are used to treat acne Sulphur ointment and also used to treat seborrheric dermatitis and
scabies.

Storage: Stored in a well closed container dark and cool place and temperature not exceeding 250C

MFG BY: ABCD Batch: Roll No.:

Label:

Report:
 Exp. No.-10 Date:
Aim: To prepare and submit 100gm of Cetrimide cream B.P.C.
Reference:
 Mehta R.M., Dispensing Pharmacy, Vallabh Prakashan, New Delhi,2017; 247
Requirements:
Apparatus Required:
Mortar & pestle, weigh balance, water bath, beaker, measuring cylinder etc.
Chemical Required:
Cetrimide, Cetostearyl alcohol, liquid paraffin and purified water.
Principle:
Creams are the semisolid product used for protection of skin. They are also used for medicinal or
beautification as a foundation for other cosmetics and for cleaning action. Thus, creams are for
external use only. The term vanishing is used for those cream and lotions which spread easily and
disappear rapidly when rubbed on the skin.

Formula:

Sl. No. Ingredients Official formula Working Required

formula quantities
1 Cetrimide 0.5gm

2 Cetostearyl alcohol 5gm

3 Liquid paraffin 50gm

4 Purified water 44.5gm 100gm

Calculation:

Procedure:
 Melt the Cetostearyl alcohol on a water bath.
 Add the liquid paraffin and heat to 600C.
 Dissolve the Cetrimide in freshly boiled and cooled purified water and warm to 600C.
 Add the aqueous solution to the oily mixture and stir until cold.
 Transfer the cream into a suitable container, label and dispense.

Storage: Store in a well closed wide mouth containers or in collapsible tubes.

Use: As foundation to other cosmetics and for beautification
Direction: To be applied on dry skin three times a day.
 Label:

CETRIMIDE CREAM B.P.C

100gm
Composition:
Cetrimide
BATCH NO.: MFG. DATE:
Cetostearyl alcohol

Liquid paraffin MFG. LIC NO.: EXPIRY DATE:

Purified water.

Category: Cosmetics

FOR EXTERNAL USE ONLY.

Use: As foundation to other cosmetics and for beautification

Storage: Stored in a well closed container at a temperature not exceeding 250C

MFG BY: ABCD Batch: Roll No.:

Report:
 Exp. No.-11 Date:
Aim: To prepare and submit 30gm of Sodium alginate gel.
Reference:
 Pharmacopoeia of India
Requirements:
Apparatus Required:
Mortar & pestle, weigh balance, measuring cylinder, glass rod, spatula, beaker etc.
Chemical Required:
Sodium alginate, Calcium chloride, Coloring agent, purified water
Principle:
A gel is a semi-solid that can have properties ranging from soft and weak to hard and tough. Gels
are defined as a substantially dilute cross-linked system, which exhibits no flow when in the steady-
state. A gel has been defined phenomenologically as a soft, solid or solid-like material consisting of
two or more components, one of which is a liquid, present in substantial quantity.

Formula:

Sl. Ingredients Official Working Required

No. formula formula quantities

1. Sodium 2%w/v
alginate
2. Calcium 5%w/v
chloride
3. Coloring agent q. s
4. Purified water 100ml 30gm

Calculation:

Procedure:
Step 1: Mix the dry, powdered sodium alginate with distilled water.
For a great gel, use 100 ml of distilled water and 1 teaspoon of sodium alginate (this is a 2%
sodium alginate solution).
Step 2: In another container, mix the calcium chloride with distilled water.
Use a heaping teaspoon of calcium chloride in 100 ml of distilled water (this is a 5% calciumchloride
solution)
Step 3: Make a gel by adding dissolved alginate to the calcium solution.
Using a spoon or a dropper, add (i.e., drop or squirt) a little of the sodium alginate solution into the
calcium chloride solution. In an instant, the calcium reacts with the sugar units in the alginate to
pull the long flexible chains of alginate into a gel.

Use: Alginate is used as an emulsifier or stabilizer.

 Storage:
It should be tightly closed and stored out of contact with water.

Label:

SODIUM ALGINATE GEL

30gm

Compositions:
Sodium alginate BATCH NO. MFG. DATE:

Calcium chloride
Colouring agent MFG. LIC. NO.: EXPIRY DATE:
Purified water
Category: Stabilizing
FOR EXTERNAL USE ONLY.
Use: used as an emulsifying, stabilizing, suspending, thickening in
Storage: Stored in a well closed container at a temperature not exceeding 250C
It should be tightly closed and stored out of contact with water
MFG BY: ABCD Batch: Roll No.:

Report:
 Exp. No.-12 Date:
Aim: To prepare and submit 30ml of Turpentine Liniment.

Reference:
Mehta R.M., Dispensing Pharmacy, Vallabh Prakashan, New Delhi, 2017;164 -165
Requirements:
Apparatus Required:
Mortar & pestle, weigh balance, measuring cylinder, glass rod, spatula, beaker, funnel etc.
Chemical Required:
Soft soap, camphor, turpentine oil, purified water.
Principle:
Liniments are solution or suspensions or emulsion intended for external application. They are
generally applied with massage. Liniment of turpentine is used externally in a patient suffering from
arthalgia, myalgia, fibrositis, and sprain.

Formula:

Sl. No. Ingredients Official formula Working formula Required quantities

1 Soft soap 9gm

2 Camphor 5gm

3 Turpentine oil 69gm

4 Purified water 1000ml 30ml

Calculation:

Procedure:
 Take the required quantity of soft soap in the mortar and add water in thrice the quantity assoft soap.
 Triturate to make a soapy solution.
 Take the required quantity of oil of turpentine in a dry measure glass and dissolve camphorin it.
 Add this solution drop by drop in the mortar and triturate continuously and rapidly till theprimary
emulsion is formed.
 Add a small quantity of water and transfer it to the previously calibrated round verticallyribbed and
blue and amber colored bottle.
 Adjust to the required volume by adding water, attach the cork and label it.

Use:
Liniment of turpentine is used externally in a patient suffering from arthalgia, myalgia, fibrositis,and
sprain.

Storage:
It should be store in a well closed container dark in a cool place.
 Label:

TURPENTINE LINIMENT
30ml
Composition:
Soft soap BATCH NO. MFG. DATE:
Camphor
MFG. LIC. NO.: EXPIRY DATE:
Turpentine oil
Purified water
Category: Arthalgia
FOR EXTERNAL USE ONLY.
Use: Liniment of turpentine is used externally in a patient suffering from arthalgia, myalgia,
fibrositis, and sprain.
Storage: Stored in a well closed container dark in a cool place and temperature not exceeding
250C
MFG BY: ABCD Batch: Roll No.

Report:
 Exp. No.-13 Date:
Aim: To prepare and submit 30ml of White Liniment BPC.
Reference:
 Mehta R.M., Dispensing Pharmacy, Vallabh Prakashan, New Delhi,2017;164 -165
 Indian Pharmacopoeia.
Requirements:
Apparatus Required:
Mortar & pestle, weigh balance, measuring cylinder, glass rod, spatula, beaker, funnel etc.
Chemical Required:
Ammonium chloride, Dil. Ammonia Solution, Oleic acid, turpentine oil, purified water
Principle:
Liniments are solution or suspensions or emulsion intended for external application. They are
generally applied with massage. Liniment of turpentine is used externally in a patients suffering from
arthalgia, myalgia, fibrositis and sprain.
Formula:
Sl. No. Ingredients Official Working formula Required quantities
formula
1 Ammoniumchloride 12.5
gm

2 Dil. AmmoniaSolution 45 ml

3 Oleic acid 83.3

ml
4 Turpentine oil 250 ml

5 Purified water 625ml 30ml

Calculation:

Procedure:
 Mix turpentine oil and oleic acid in a bottle.
 Add an equal volume of warm water (50 ºC) to a dilute ammonia solution. Then add thisdilute solution
(in small amount to the oily liquid, shake vigorously after each addition.
 Dissolve the ammonium chloride in the rest of the water and add it to the bottle (in smallamount) and
shake vigorously after each addition.

Use: White Liniment is a rubefacient, which is a substance that warms the skin. It is used for relief
from sciatica. Sprains, lumbago and rheumatoid pains,

Storage: It should be store in a well closed container dark in a cool place.

 Label:
WHITE LINIMENT BPC
30ml
Composition:
Ammonium Chloride BATCH NO. MFG. DATE:
Dil. Ammonia Solution
MFG. LIC. NO.: EXPIRY DATE:
Oleic Acid
Turpentine oil
Purified water
Category: Arthalgia
FOR EXTERNAL USE ONLY.
Use: White liniment is used for the relief of sciatica, sprains, lumbago and rheumatic pains.

Storage: Stored in a well closed container dark in a cool place and temperature not exceeding
250C

MFG BY: ABCD Batch: Roll No.

Report:
 Exp. No.-14 Date:
Aim: To prepare and submit 10gm of Effervescent granules.
Reference:
 Mehta R.M., Dispensing Pharmacy, Vallabh Prakashan, New Delhi, 2017; 127
 Subrahmanyam C.V.S., Thimmasetty. J, Prabhushankar G.L., Laboratory manual of Pharmaceutics.
Vallabh Publication, Delhi, 2019; 88
Requirements:
Apparatus Required:
Mortar & pestle, weigh balance sieve shaker, China dish etc.
Chemical Required:
Sodium phosphate, sodium bicarbonate, tartaric acid.
Principle:
Effervescent preparation provides effervescence of CO2 gas when added to water by a chemical
reaction between alkali metal carbonates or bicarbonates with tartaric acid or citric acid. This
preparation is intended to be dissolved in water before it is being taken orally. The CO2 gas is released
as a result of acid-base reaction. The preparation is advised to be taken while effervescence.

Formula:
Sl. No. Ingredients Official formula Working Required quantities
formula
1 Sodium phosphate 0.9gm
2 Sodium bicarbonate 2.1gm
3 Tartaric acid 1.1gm
4 Citric acid 0.7gm 10gm

Calculation:

Procedure:

 Citric acid is mixed with sodium phosphate and tartaric acid.

 Add sodium bicarbonate to the above mixture and mix it gently.
 The final powdered mixture is placed in a China dish previously heated on water bath.
 Stir the mixture with the help of a spatula constantly still it becomes damp mass.
 Pass damp mass through sieve number 8.
 Dry granules at a room temperature not exceeding 540C.
 Pass dry granules through appropriate sieve.
 Pack dry uniform sized granules in a wide mouthed bottle.

Dose: Each 5g contains sodium phosphate 1g.

 Storage: Stored in air tight container in a cool place,

Use: Saline purgative and mild diuretic.

Label:

EFFERVESCENT GRANULES
10gm
Composition:
Sodium phosphate BATCH NO. MFG. DATE:
Sodium bicarbonate
Tartaric acid
MFG. LIC. NO.: EXPIRY DATE:
Citric acid
Category: Saline purgative and Mild diuretic
FOR INTERNAL USE ONLY.
Use: Saline purgative and Mild diuretic
Storage: Stored in a well closed air tight container in a cool place and temperature not exceeding
250C
MFG BY: ABCD Batch: Roll No.:

Report: