Course Curriculum
Course Code: BIOT403 Credit Units L T P/S SW AS/DS FW No. of PSDA Total Credit Unit
Course Level UG 3 0 2 2 0 0 0 5
Course Title Developmental Biology and Endocrinology
Course Course will provide knowledge of early development in humans under physiological and pathological conditions.
Description :
Course Objectives :
SN. Objectives
1 The aim of this course is to develop knowledge of early development in humans under physiological and pathological conditions.
Pre-Requisites : General
SN. Course Code Course Name
Course Contents / Syllabus :
Modul
SN. Descriptors / Topics Weightage
e
Basics of Developmental Biology: The origins of developmental biology, Concepts in early stage development,
Developmental signals in cell division & differentiation, Cell commitment & differentiation, Determination & induction of cell
1 I 20.00
fate, Importance of hormones in growth and Human health. Significance of endocrine system in the developmental Biology
in human
Endocrine system and reproductive physiology: Different types of Hormones and their biological characteristics, Role of
hypothalamus, anterior and posterior pituitary in hormone release, Role of hormones in reproductive system, fertilization
2 II 30.00
and gametogenesis. Regulation of gonadotropins in reproductive physiology, Hormonal changes at puberty and
Adolescence and their feedback control
Early Embryonic Development: Conversion of germ cells into male and female gametes, fertilization, mechanism of
fertilization, acrosomal reactions, sperm capacitation, vittelogenesis, sperm specificity, egg-sperm metabolism, fast and
3 III slow block to polyspermy, concept of pattern formation, axis formation, origin and specification of fate map Blastulation, 30.00
formation of bilaminar disc, Cleavage patterns, gastrulation (General principles and outline of the physiology) , Neurulation,
origin and fate of neural crest cells, formation of trilaminar disc
pathology related to Hormonal disturbances in Humans: Pathological disorders due to the hormonal imbalance (poly cystic
4 IV ovaries, hypertension, insulin resistance, menstrual cycle disturbances, endometriosis, male and female infertility), Anxiety 10.00
and Depression, Iodine deficiency . Teratolological defects, Neural tube defects and congenital diseases.
5 V Assisted Reproductive Technology: In Vitro Fertilization and Intra uterine insemination 10.00
Course Learning Outcomes :
SN. Course Learning Outcomes
1 Identify concepts, principles, and responses related to developmental biology.
Interpret the structural and functional alterations in cells, tissues, and organs that are present in selected diseases during developmental
2
processes
3 Apply principles of endocrinology of human body systems in the development and growth processes
4 Describe the etiology, pathophysiologic process, and clinical manifestations of identified developmental and endocrinological disorders
5 Analyse and explore the most common disorders and diseases related to each of the major body systems
Build appropriate inferences and Design integrated assignments for probable solutions using integrative parameters of basic developmental and
6
endocrinological studies for healthcare management.
Pedagogy for Course Delivery :
SN. Pedagogy Methods
1 lectures
2 Presentations / seminars
3 Class Tests
Theory /VAC / Architecture Assessment (L,T & Self Work): 80.00 Max : 100
Attendance+CE+EE : 5+35+60
SN. Type Component Name Marks
1 Attendance 5.00
2 End Term Examination (OMR) 60.00
3 Internal CLASS TEST 10.00
4 Internal INTEGRATED ASSIGNMENT 15.00
5 Internal CLASS QUIZ 5.00
6 Internal PRESENTATION 5.00
Lab/ Practical/ Studio/Arch. Studio/ Field Work Assessment : 20.00 Max : 100
Attendance+CE+EE : 5+35+60
SN. Type Component Name Marks
1 Attendance 5.00
2 External END SEMESTER PRACTICAL EXAMINATIONS 60.00
3 Internal CLASS TEST (PRACTICAL BASED) 10.00
4 Internal PRACTICAL / LAB RECORDS 5.00
5 Internal Viva 10.00
6 Internal CLASS QUIZ 10.00
Lab/ Practical details, if applicable :
SN. Lab / Practical Details
1 1. Pattern of cleavages in different organisms ( Discoidal cleavage in chick)
2 2. Study of embryonic and Post embryonic development using a model system (/Zebra Fish chick/frog)
3 3. Mounting of chick embryo and preparation of permanent slide
4 4. Filter paper ring method of in vitro isolation of chick embryo
5 5. Gross anatomy and histology of chick embryo till 96hrs.
6 6. Estimation of human chorionic gonadotropin hormone in a given biological sample
7 7. Estimation of Follicle stimulating hormone and luteinizing hormone in a given biological sample
8 8. To check the pregnancy using strip method
9 9. Study the permanent slides of mammalian ovary and testes and preparation
List of Professional skill development activities :
No.of PSDA : 3
SN. PSDA Point
1 quiz
2 group discussion
3 integrated assignment
Text & References :
SN. Type Title/Name Description ISBN/ URL
• Langman’s Medical Embryology 12th
1 Book edition T.W Sadler Wolter ISBN 0-7506-2030-7
Klewer/Lippincott. Williams& Wilkinsio
• Text Book of Human Embryology , Rani
ISBN:
2 Book Kumar, IK International publisher, New
9788190675710
Delhi, (2008).
• Gilbert’s Development Biology (6th ISBN-13: 978-
3 Book
edition) by Scott.F.Gilbert. (2000). 0878932436
• Williams Text Book of Endocrinology, 12th
ISBN-13: 978-
4 Book Edition, By Shlomo Melmed, Kenneth S.
1437703245
Polonsky, MD, P.
