Blood Supply to the Brain
and Spinal Cord
Dr. Sanyaolu
Overview of Brain Blood Supply
• Brain receives ~15% of cardiac
output
• Supplied by two major arterial
systems:
• Internal carotid system (anterior
circulation)
• Vertebrobasilar system (posterior
circulation)
Internal Carotid System(Anterior Circulation)
• Supplies ~80% of cerebral blood flow.
• from the common carotid arteries-
bifurcate into the ICA & ECA at C3–C4.
• Branches ICA:
✓Ophthalmic artery
✓Posterior communicating artery
✓Anterior choroidal artery
✓Terminal branches:
• Anterior Cerebral Artery (ACA)
• Middle Cerebral Artery (MCA): supplies
lateral surface of frontal, parietal, & temporal
lobes.
Vertebrobasilar System (Posterior Circulation)
• Supplies ~20% of cerebral blood flow.
• Vertebral arteries-from the subclavian
arteries, ascend through the transverse
foramina of cervical vertebrae (C6–C1), &
enter the skull via foramen magnum.
• 2 vert. arteries forms the basilar artery
which ascends along the ventral pons &
terminates as post. cerebral arteries (PCA).
Key branches:
✓Post. Inf. Cerebellar Artery (PICA)
✓Ant. Inf. Cerebellar Artery (AICA)
✓Sup. Cerebellar Artery (SCA)
✓Post. Cerebral Artery (PCA)
Circle of Willis
• A circular anastomosis at the base
of the brain that connects the
anterior and posterior circulation.
• Components:
• Internal carotid artery (ICA)
• Anterior cerebral artery (ACA)
• Anterior communicating artery
(AComm)
• Posterior cerebral artery (PCA)
• Posterior communicating artery
(PComm)
Function: Collateral circulation to
maintain perfusion if one vessel is
occluded.
Major Cerebral Arteries & Their
Territories
• Anterior cerebral artery (ACA)-
Medial frontal/parietal lobes; lower
limbs
• Middle cerebral artery (MCA)-
Lateral cortex; face, upper limb,
language areas
• Posterior cerebral artery (PCA)-
Occipital lobe, inf. temporal lobe,
thalamus.
Stroke Relevance:
•MCA infarct → contralateral face/arm weakness + aphasia
•ACA infarct → leg weakness
•PCA infarct → visual field loss
Deep Perforating Arteries
• Lenticulostriate arteries
(from MCA): supply basal
ganglia and internal
capsule
• Clinical: prone to lacunar
strokes
Venous Drainage of the Brain
• Superficial cerebral veins →
superior sagittal sinus
• Deep veins (e.g., internal
cerebral vein) → straight sinus
• Drain into internal jugular
vein via transverse & sigmoid
sinuses
• Clinical Note: Dural venous
sinus thrombosis → ↑
intracranial pressure
Spinal Cord Blood Supply
• Anterior spinal artery (from
vertebral arteries)
• Supplies anterior 2/3 of spinal
cord (motor)
• Posterior spinal arteries (paired,
from PICA or vertebral)
• Supply posterior 1/3
(sensory)
• Radicular arteries, including:
• Artery of Adamkiewicz (T9–
L2): major lower cord supply
Clinical Note: Ischemia of anterior spinal artery →
anterior cord syndrome (motor paralysis, sensory loss)
Clinical Correlations
• Stroke syndromes
(MCA/ACA/PCA)
• Aneurysms of Circle of
Willis
• Anterior spinal artery
syndrome
• Subarachnoid hemorrhage
(often ruptured aneurysm)