OSPE
OSPE
(20 marks)
ONE Performance THREE Response
station Stations
(5 marks) (15 marks)
PERFORMANCE STATION
- 5 marks
STATION
4 year boy presented with generalised oedema and facial
puffiness.
Perform the relevant qualitative test on the given urine
sample and report.
SR NO STEP/ TASK PERFORMED?
1. Takes 10 ml of urine in a test tube
Heats the upper part of the urine over burner
2. and allows it to boil. Keeps the mouth of the test
tube away from face to prevent scalding.
Adds 1% acetic acid to the test tube, drop by
3. drop.
Records observation and interprets the result
4.
Discards the sample and keeps the work area
5. clean
STATION
50 year old male patient presented to the OPD with yellowish
discolouration of skin and passage of clay colored stools.
Perform the relevant qualitative test on the given urine
sample and report.
SR NO STEP/ TASK PERFORMED?
1. Takes 2 ml of urine in a test tube
Adds a pinch of sulphur powder
2.
Observes the sample without mixing
3.
4. Records observation and interprets the result
Discards the sample and keeps the work area
5. clean
STATION
60 year old female comes to the Medicine OPD with
complaints of increased appetite, thirst and frequency of
urination.
Perform the relevant qualitative test on the given urine
sample and report.
SR NO STEP/ TASK PERFORMED?
1. Takes 5 ml of Benedict’s reagent in a test tube
Adds 8 drops of urine sample to the test tube
2. and mixes the solution well.
Boils the solution for 2 minutes and allows it to
3. cool
4. Records observation and interprets the result
Discards the sample and keeps the work area
5. clean
STATION
56 year old female diabetic patient comes with decreased
urine output. The nephrologist ordered for the estimation of
GFR.
Perform the relevant qualitative test on the given urine
sample and report.
SR NO STEP/ TASK PERFORMED?
Takes two test tubes. Add 5ml of urine in to one
1. and 5ml of water into the other.
Adds 2ml of 2% picric acid to both the test tubes
2.
Adds few drops of 5% NaOH solution to both test
3. tubes.
Records observation and interprets the result
4.
Discards the sample and keeps the work area
5. clean
RESPONSE STATION
- 5 marks each
STATION
• Name the disorder (1)
• Mention the nutrient which is
deficient. (1)
• Write the active form of the
nutrient. (1)
• Write the RDA of the nutrient in
adults and children. (2)
ANSWERS
• Rickets
• Vitamin D
• 1,25 dihydroxycholeciferol
• Adults : 5 micrograms /day (200 IU)
Children : 10 micrograms/day (400 IU)
STATION
• Identify the condition (1)
• Mention the deficient nutrient.
(1)
• List two functions of the
nutrient (2)
• List two dietary sources of the
nutrient (1)
ANSWERS
• Bitot’s spot
• Vitamin A
• Plays a role in vision and dark adaptation, gene regulation,
necessary for reproductive system, antioxidant property,
maintenance of normal epithelium and skin, role in regulation of
gene expression
• Fish liver oil, carrot, papaya, mango
STATION
A 50 year old man has come to the
medicine OPD with pain and swelling
of the great toe. No history of trauma
present.
• What is the probable diagnosis? (1)
• Which biochemical parameter is
likely to increase? (1)
• Mention its normal value (1)
• List two drugs given as treatment (2)
ANSWERS
• Gout.
• Serum uric acid
• Male: 3.5 – 7 mg/dl
Female : 2.5 – 5 mg/dl
• Uricosuric drugs ex: probenecid
Allopurinol
STATION
• Name the condition (1)
• Mention the deficient nutrient (1)
• List two dietary sources of the
nutrient. (2)
• List one function of the nutrient (1)
ANSWERS
• Pellagra
• Niacin
• Dried yeast, rice polishing, peanuts, whole cereals, legumes, etc
• Forms NAD+ and NADP+ which act as coenzymes
STATION
• Name the disorder (1)
• Mention the deficient nutrient (1)
• What is the daily requirement for
the nutrient in adults? (1)
• What is the cause for oedema in
children with this condition? (2)
ANSWERS
• Kwashiorkar (Protein energy malnutrition)
• Protein
• 0.8 g/kg body weight
• Decreased colloidal osmotic pressure due to decreased serum
albumin.
STATION
• Identify the condition having this
feature (1)
• Mention the nutrient involved. (1)
• List two enzymes containing the
nutrient (2)
• List two dietary sources of the
nutrient (1)
ANSWERS
• Wilson’s disease
• Copper
• Ceruloplasmin, cytochrome oxidase, cyt c, tyrosinase, lysyl oxidase,
ALA synthase, etc
• Cereals, meat, liver, nuts, green leafy vegetables
STATION
The acid base parameters of a patient is as follows –
Blood pH = 7.14
pCO2 = 82 mmHg
HCO3 = 26 mEq/L
• What is the acid base disturbance? (1)
• Name two causes for the condition? (2)
• List the normal values for : pCO2 and HCO3 (2)
ANSWERS
• Uncompensated respiratory acidosis
• Pneumonia, Asthma, etc
• 35 – 45 mmHg, 22 – 26 mEq/L
STATION
The acid base parameters of a patient is as follows –
Blood pH = 7.56
pCO2 = 48 mmHg
HCO3 = 31 mEq/L
• What is the acid base disturbance? (1)
• Name two causes for the condition? (2)
• List the normal values for : pCO2 and HCO3 (2)
ANSWERS
• Partially compensated metabolic alkalosis
• Severe vomiting, cushing syndrome, milk alkali syndrome, etc
• 35 – 45 mmHg, 22 – 26 mEq/L
STATION
The acid base parameters of a patient is as follows –
Blood pH = 7.32
pCO2 = 31 mmHg
HCO3 = 16 mEq/L
• What is the acid base disturbance? (1)
• Name two causes for the condition? (2)
• List the normal values for : pCO2 and HCO3 (2)
ANSWERS
• Partially compensated metabolic acidosis
• Diabetic ketoacidosis, lactic acidosis, renal failure, etc
• 35 – 45 mmHg, 22 – 26 mEq/L
STATION
The serum protein electrophoresis gel scan is given below:
• Interpret the slide (1)
• Mention the normal values of serum protein and serum albumin (2)
• List 2 functions of serum albumin (2)
ANSWERS
• Normal protein electrophoresis
• 6-8 g/dl , 3.5 -5 g/dl
• Maintainence of colloidal osmotic pressure, transport various
hydrophobic substances (bilirubin, NEFA, drugs, hormones,etc),
buffering action, nutritional importance.
STATION
The serum protein electrophoresis gel scan is given below:
• Interpret the slide (1)
• Mention the normal values of serum protein and serum albumin (2)
• List 2 functions of serum albumin (2)
ANSWERS
• Multiple myeloma
• 6-8 g/dl , 3.5 -5 g/dl
• Maintainence of colloidal osmotic pressure, transport various
hydrophobic substances (bilirubin, NEFA, drugs, hormones,etc),
buffering action, nutritional importance.
