PATHOLOGY : THEORY PAPER WISE COURSE DISTRIBUTION
Paper 1: 1. Introduction to Pathology:
Describe role of Pathologist in diagnosis and management of Disease, common
definition and terms used, history and evolution of pathologist.
2. Cell injury and Adaption:
Types of Cell injury, intracellular accumulation of fat, Protein, carbohydrate,
pigments, Types of Cell death : Necrosis and apoptosis, autolysis, Calcification,
Gangrin, Cellular adaptation: Atrophy, Hypertrophy, hyperplasia, Metaplasia,
Dysplasia, Cellular aging, Amylodosis.
3. Inflammation, Healing and repair:
Acute and chronic inflammation, Chemical Mediators, Chronic
Inflammation:Types, Granulomatas Repair, regeneration and wound healing.
4. Hemodynamic disorders:
Edema, Hyperemia, Congestion, Hemorrhage, Shocks: Types, stages and
pathogenesis, Normal Hemostasis, Thromosis, Embolism, Ischemia/Infarction :
Types etiology.
5. Neoplasia:
Define and classify, Benign Vs Malignant neoplasim , Molecular basis of Cancer,
Carcinogens, Paraneoplastic syndromes, immunology and Immune response to
cancer, Diagnositic Role of Cytology and its application, Exfolative cytology.
6. Immunopathology and AIDS:
Principles and mechanisms in immunity, hypersensitivity reactions, HLA
systems, Transplant immunity and transplant rejection, Autoimmunity and
autoimmune disorders, SLE: Pathogenesis, HIV and AIDS: Pathogenesis and
Pathology.
7. Infections and infestations:
Malaria, Cysticercoids, leprosy, Common Bacterial, Viral, Protozoal and
helminthic diseases.
8. genetic and paediatric diseases:
Common cytogenetic abnormalities and mutations in childhood, Pathology of
Tumor and tumor like condition in infancy and childhood, Common storage
disorders.
9. Environmental and nutritional Diseases:
Disorders caused by air pollution, Tobacco and Alcohol, Protein calorie
malnutrition and starvation, Obesity and its consequences.
HAEMATOLOGY:
1. Introduction to Haematology
Haematopoisis and extra medullar Haematopoiesis, Role of Anti coagulants,
Define and classify anemia.
2. Microcytic Anemia: Iron Metabolism, Lab Investigation and Differential
Diagnosis of Microcytic Anemia.
3. Macrocytic Anemia:
Vitamin B12 Metabolism, Lab Investigation, etiology and D/D of Megaloblstic
and Non Megaloblastic anemia.
4. Haemolytic anemia:
Classify Haemolytic Anemia, Sickle Cell Anemia, Thalassemia, Acquired
Haemolytic Anemia.
5. Aplastic Anemia:
6. Leukocyte disorders:
Causes of Leukocytosis, Leucopoenia, Leukemoid reaction, Acute and
chronic Leukaemia.
7. Lymph node and spleen:
Causes of Lymphoadenopathy , TB Lymphadenitis, Hodgkins nad Non
Hodgkins Lymphoma, Causes of Splenomegaly.
8. Plasma Cell Disorders:
Plasma Cell Myeloma.
9. Hemorrhagic disorders:
Normal Haemostasis, Vascular and Platelet Disorders: ITP and
Hemophilia, Clotting Disorders, DIC, Lab Findings of Vitamin K
Deficiency.
10. Blood Banking and transfusion:
Classify Blood Group systems(ABO and RH), Compatibility Testing, Blood
Components, Infection Transmitted, Transfusion reactions, Autologus
Transfusion.
CLINICAL PATHOLOGY:
1. Common Urinary Abnormalities, Body Fluids in various disease,
Semen Analysis, Thyroid Function Test, Renal Function Test, Liver
Function Test.
Paper II: SYSTEMIC PATHOLOGY :
1. Gastro intestinal tract:
Oral Cancer, Peptic Ulcer Disease, Carcinoma of Stomach, TB of
intestine, Inflammatory bowel Diseases, Carcinoma of Colon.
2. Hepatobiliary systems:
Bilirubin Metabolim, Jaundice, Hepatic Failure, viral and
toxic hepatitis, Alcoholic Liver disease, cirrhosis, Portal
Hypertension, Obstructive and non obstructive jaundice.
3. Respiratory Systems:
Pneumonia, Lung Abscess, obstructive Airway disease,,
Bronchiectasis, Tuberculosis, Occupational Lung
Diseaseas, Tumors of Lung and Pleura, Mesothelioma.
4. Cardiovascular systems:
Arteriosclerosis, Atherosclerosis, Aortic aneurysm, Heart
Failure, Rheumatic Fever, Ischemic heart disease, infective
endocarditic, Pericarditis and pericardial effusion, Cardiac
Function Testing in acute Coronary syndrome,
Cardiomyopathies, Complication of Syphillis on CVS.
5. Urinary Tract:
Renal Failure, ARF, CRF, Glomerular Diseases and
Glomerulonephritis, IgA Nephropathy, Tubulo Interstitial
diseases, Acute Tubular Necrosis, Acute and Chronic
Pyelonephritis, Reflux nephropathy, Vascular Diseases of
Kidney, Cystic Diseases, Renal Stone Diseseas and
Obstructive Uropathy, Renal Tumors, Thrombotic
angiopathy, Urothelial tumors.
6. Male Genital Tract:
Testicular Tumors, Carcinoma of Penis, BHP, Carcinoma
of Prostrate, Prostatis.
7. Female Genital Tract:
Carcinoma of Cervix and Endometrium, Leiomyoma and
Leiomyosarcoma, Ovarian Tumors, Gestational
Trophoblastic Neoplasms, Cervicitis, Endometriosis,
adenomyosis, Endometrial hyperplasia.
8. Breast:
Benign breast diseases, Carcinoma of Breast,
Gynecomastia.
9. Endocrine systems:
Classify thyroid Swellings, Thyrotoxicosis, Hypothyroism,
diabetis Mellitus, Hyperparathyroidism, Pancreatic Cancer,
adrenal insufficiency, Cushing syndrome, Adrenal
Neoplams.
10. Bone and soft Tissue:
Osteomyeltis, Bone Tumors, Soft Tissue tumors,pagets
disease of Bone, Rheumatoid Arthritis.
11. Skin:
Squamous cell carcinoma of skin, basal Cell carcinoma,
Mellanoma,.
12. Central Nervous Systems:
CSF finding in meningitis, CNS Tumors, Retinoblastoma
