CONTENTS

Introduction – Hepatobiliary and pancreatic surgery: Historical perspective, Pages 1-15.e5

Chapter 1 – Embryologic development of the liver, biliary tract, and pancreas, Pages 17-.e4
Chapter 2 – Surgical and radiologic anatomy of the liver, biliary tract, and pancreas, Pages 32-59.e1
Chapter 3 – Assessment of hepatic function: Implications for the surgical patient, Pages 60-65.e2
Chapter 4 – Pancreatic Physiology and Functional Assessment, Pages 66-76.e3
Chapter 5 – Liver blood flow: Physiology, measurement, and clinical relevance, Pages 77-92.e5
Chapter 6 – Liver regeneration: Mechanisms and clinical relevance, Pages 93-109.e7
Chapter 7 – Liver fibrogenesis: Mechanisms and clinical relevance, Pages 110-122.e5
Chapter 8 – Bile secretion and pathophysiology of biliary tract obstruction, Pages 123-132.e1
Chapter 9A – Advances in the molecular characterization of liver tumors, Pages 133-138.e2
Chapter 9B – Molecular pathology of pancreatic cancer and premalignant tumors, Pages 139-149.e3
Chapter 9C – Molecular pathogenesis of biliary tract cancer, Pages 150-159.e2
Chapter 9D – Molecular biology of liver carcinogenesis and hepatitis, Pages 160-172.e3
Chapter 10 – Liver immunology, Pages 173-187.e2
Chapter 11 – Cytokines in liver, biliary, and pancreatic disease, Pages 188-200.e3
Chapter 12 – Infections in hepatic, biliary, and pancreatic surgery, Pages 201-222.e3
Chapter 13 – Clinical investigation of hepatopancreatobiliary disease, Pages 224-238.e2
Chapter 14 – Emerging techniques in diagnostic imaging, Pages 239-244.e1
Chapter 15 – Ultrasound of the liver, biliary tract, and pancreas, Pages 245-275.e4
Chapter 16 – Endoscopic ultrasound of the biliary tract and pancreas, Pages 276-284.e2
Chapter 17 – Role of nuclear medicine in diagnosis and management of hepatopancreatobiliary disease, Pages
285-315.e3
Chapter 18 – Computed tomography of the liver, biliary tract, and pancreas, Pages 316-357.e6
Chapter 19 – Magnetic resonance imaging of the liver, biliary tract, and pancreas, Pages 358-377.e2
Chapter 20 – Direct cholangiography: Approaches, techniques, and current role, Pages 378-391.e3
Chapter 21 – Diagnostic angiography in hepatobiliary and pancreatic disease: Indications, Pages 392-402.e1
Chapter 22 – Percutaneous biopsy, Pages 403-412.e2
Chapter 23 – Intraoperative diagnostic techniques, Pages 413-421.e2
Chapter 24 – Intraoperative and immediate postoperative management, Pages 423-436.e3
Chapter 25 – Perioperative critical care in hepatopancreatobiliary patients, Pages 437-444.e4
Chapter 26 – Preoperative and postoperative nutrition in hepatobiliary surgery, Pages 445-458.e5
Chapter 27 – Postoperative complications requiring intervention: Diagnosis and management, Pages 459-
474.e3
Chapter 28 – Quality of life and hepatobiliary tumors, Pages 475-509.e3
Chapter 29 – Interventional endoscopy: Technical aspects, Pages 511-524.e4
Chapter 30 – Radiologic hepatobiliary interventions, Pages 525-536.e1
Chapter 31 – Bile duct exploration and biliary-enteric anastomosis, Pages 537-548.e1
Chapter 32 – Natural history of gallstones and asymptomatic gallstones, Pages 551-555.e2
Chapter 33 – Cholecystitis, Pages 556-563.e2
Chapter 34 – Percutaneous treatment of gallbladder disease, Pages 564-568.e1
Chapter 35 – Technique of cholecystectomy: Open and minimally invasive, Pages 569-584.e2
Chapter 36A – Stones in the bile duct: Clinical features and open surgical approaches and techniques, Pages
585-603.e3
Chapter 36B – Stones in the bile duct: Minimally invasive surgical approaches, Pages 604-610.e1
Chapter 36C – Stones in the bile duct: Endoscopic and percutaneous approaches, Pages 611-622.e3
Chapter 37 – Cholecystolithiasis and stones in the common bile duct: Which approach and when?, Pages 623-
632.e3
Chapter 38 – Postcholecystectomy problems, Pages 633-641.e4
Chapter 39 – Intrahepatic stones, Pages 642-655.e3
Chapter 40 – Extrahepatic biliary atresia, Pages 656-662.e2
Chapter 41 – Primary sclerosing cholangitis, Pages 663-674.e5
Chapter 42 – Biliary fistulae and strictures, Pages 675-713.e9
Chapter 43 – Cholangitis, Pages 714-724.e2
Chapter 44 – Recurrent pyogenic cholangitis, Pages 725-741.e2
Chapter 45 – Biliary parasitic disease, Pages 742-751.e3
Chapter 46 – Bile duct cysts in adults, Pages 752-764.e3
Chapter 47 – Tumors of the biliary tree: Pathologic features, Pages 765-774.e3
Chapter 48 – Benign tumors and pseudotumors of the biliary tract, Pages 775-785.e3
Chapter 49 – Tumors of the gallbladder, Pages 786-804.e5
Chapter 50 – Intrahepatic cholangiocarcinoma, Pages 805-817.e5
Chapter 51A – Extrahepatic bile duct tumors, Pages 818-832.e3
Chapter 51B – Perihilar cholangiocarcinoma with emphasis on presurgical management, Pages 833-845.e2
Chapter 52 – Interventional techniques in hilar and intrahepatic biliary strictures, Pages 846-859.e1
Chapter 53 – Congenital disorders of the pancreas: Surgical considerations, Pages 861-874.e4
Chapter 54 – Definition and classification of pancreatitis, Pages 875-882.e1
Chapter 55 – Etiology, pathogenesis, and diagnostic assessment of acute pancreatitis, Pages 883-896.e3
Chapter 56 – Management of acute pancreatitis and complications, Pages 897-910.e2
Chapter 57 – Etiology, pathogenesis, and diagnosis of chronic pancreatitis, Pages 911-926.e3
Chapter 58 – Management of chronic pancreatitis: Conservative, endoscopic, and surgical, Pages 927-937.e3
Chapter 59 – Pancreatic and periampullary tumors: Classification and pathologic features, Pages 938-957.e6
Chapter 60 – Cystic neoplasms of the pancreas: Epidemiology, clinical features, assessment, and management,
Pages 958-970.e2
Chapter 61 – Pancreatic cancer: Epidemiology, Pages 971-978.e2
Chapter 62 – Pancreatic cancer: Clinical aspects, assessment, and management, Pages 979-987.e2
Chapter 63 – Duodenal adenocarcinoma, Pages 988-991.e1
Chapter 64 – Pancreas as a site of metastatic cancer, Pages 992-996.e1
Chapter 65 – Pancreatic neuroendocrine tumors: Classification, clinical picture, diagnosis, and therapy, Pages
997-1006.e3
Chapter 66 – Techniques of pancreatic resection: Pancreaticoduodenectomy, distal pancreatectomy, segmental
pancreatectomy, total pancreatectomy, and transduodenal resection of the papilla of vater, Pages 1007-1023.e3
Chapter 67 – Minimally invasive pancreatic resectional techniques, Pages 1024-1031.e1
Chapter 68 – Chemotherapy and radiotherapy for pancreatic cancer: Adjuvant, neoadjuvant and palliative,
Pages 1032-1041.e3
Chapter 69 – Palliative treatment of pancreatic and periampullary tumors, Pages 1042-1053.e3
Chapter 70 – Chronic hepatitis: Epidemiology, clinical features, and management, Pages 1058-1064.e2
Chapter 71 – Hepatic steatosis, steatohepatitis, and chemotherapy-related liver injury, Pages 1065-1072.e3
Chapter 72 – Pyogenic liver abscess, Pages 1073-1082.e2
Chapter 73 – Amebiasis and other parasitic infections, Pages 1083-1101.e5
Chapter 74 – Hydatid disease of the liver, Pages 1102-1121.e3
Chapter 75 – Simple cysts and polycystic liver disease: Clinical and radiographic features, surgical and
nonsurgical management, Pages 1122-1147.e3
Chapter 76 – Cirrhosis and portal hypertension: Pathologic aspects, Pages 1148-1160.e2
Chapter 77 – Nonhepatic surgery in the cirrhotic patient, Pages 1161-1167.e3
Chapter 78 – Portal hypertension in children, Pages 1168-1174.e1
Chapter 79 – Management of liver failure, Pages 1175-1180.e1
Chapter 80 – Support of the failing liver, Pages 1181-1188.e3
Chapter 81 – Management of ascites in cirrhosis and portal hypertension, Pages 1189-1195.e2
Chapter 82 – Medical management of bleeding varices: primary and secondary prophylaxis of bleeding, Pages
1196-1202.e3
Chapter 83 – Portal hypertensive bleeding: Acute management, Pages 1203-1206.e1
Chapter 84 – Portal hypertensive bleeding: Operative devascularization, Pages 1207-1217.e3
Chapter 85 – Portal hypertensive bleeding: The place of portosystemic shunting, Pages 1218-1230.e3
Chapter 86 – Technique of portosystemic shunting: Portocaval, distal splenorenal, mesocaval, Pages 1231-
1239.e1
Chapter 87 – Transjugular intrahepatic portosystemic shunting: Indications and technique, Pages 1240-1247.e3
Chapter 88 – Budd-Chiari syndrome and veno-occlusive disease, Pages 1248-1271.e6
Chapter 89 – Tumors of the liver: Pathologic aspects, Pages 1272-1298.e7
Chapter 90A – Benign liver lesions, Pages 1299-1317.e5
Chapter 90B – Cystic hepatobiliary neoplasia, Pages 1318-1332.e3
Chapter 91 – Hepatocellular carcinoma, Pages 1333-1338.e2
Chapter 92 – Hepatic metastasis from colorectal cancer, Pages 1339-1354.e4
Chapter 93 – Hepatic metastasis from neuroendocrine cancers, Pages 1355-1367.e4
Chapter 94 – Noncolorectal nonneuroendocrine metastases, Pages 1368-1377.e2
Chapter 95 – Hepatic tumors in childhood, Pages 1378-1397.e6
Chapter 96A – Hepatic artery embolization and chemoembolization of liver tumors, Pages 1398-1416.e4
Chapter 96B – Radioembolization for liver tumors, Pages 1417-1425.e2
Chapter 97 – External beam radiotherapy for liver tumors, Pages 1426-1432.e1
Chapter 98A – Ablative treatment of liver tumors: Overview, Pages 1433-1435.e1
Chapter 98B – Radiofrequency ablation of liver tumors, Pages 1436-1447.e3
Chapter 98C – Microwave ablation and irreversible electroporation, Pages 1448-1458.e2
Chapter 98D – Cryotherapy and ethanol injection, Pages 1459-1469.e2
Chapter 99 – Regional chemotherapy for liver tumors, Pages 1470-1487.e3
Chapter 100 – Systemic chemotherapy for hepatic colorectal cancer: Impact on surgical management, Pages
1488-1501.e5
Chapter 101 – Advances in systemic therapy for hepatocellular carcinoma, Pages 1502-1513.e4
Chapter 102 – Isolated hepatic perfusion for extensive liver cancer, Pages 1514-1519.e1
Chapter 103A – Hepatic resection: General considerations, Pages 1520-1521.e1
Chapter 103B – Hepatic resection for benign disease and for liver and biliary tumors, Pages 1522-1571.e4
Chapter 103C – Standard and extended resections for perihilar cholangiocarcinoma, Pages 1572-1577.e1
Chapter 103D – Liver resection in cirrhosis, Pages 1578-1586.e3
Chapter 104 – Resection technique for live-donor transplantation, Pages 1587-1596.e1
Chapter 105 – Minimally invasive techniques in hepatic resection, Pages 1597-1611.e1
Chapter 106 – Vascular isolation techniques in hepatic resection, Pages 1612-1622.e2
Chapter 107 – Vascular reconstruction techniques, Pages 1623-1630.e2
Chapter 108A – Parenchymal preservation in hepatic resectional surgery: Rationale and indications, Pages
1631-1643.e2
Chapter 108B – Segment-oriented anatomic liver resections, Pages 1644-1652.e1
Chapter 108C – Preoperative portal vein embolization: Technique and results, Pages 1653-1663.e2
Chapter 108D – Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS), Pages 1664-
1669.e2
Chapter 109 – Ex vivo and in situ hypothermic hepatic resection, Pages 1670-1683.e1
Chapter 110 – Adjuncts to hepatic resection: Ultrasound and intraoperative navigation, Pages 1684-1724.e3
Chapter 111 – Liver and pancreas transplantation immunobiology, Pages 1726-1736.e3
Chapter 112 – Liver transplantation: Indications and general considerations, Pages 1737-1749.e2
Chapter 113 – Liver transplantation: Anesthesia, perioperative management, and postoperative care, Pages
1750-1765.e5
Chapter 114 – Liver transplantation in patients with fulminant hepatitis, Pages 1766-1780.e4
Chapter 115A – Liver transplantation for hepatocellular carcinoma, Pages 1781-1790.e4
Chapter 115B – Liver transplantation for nonhepatocellular malignant disease, Pages 1791-1800.e2
Chapter 116 – Orthotopic liver transplantation, Pages 1801-1815.e5
Chapter 117 – Living-donor liver transplantation: Indications, outcomes, and surgical considerations, Pages
1816-1833.e4
Chapter 118 – Liver transplantation in children, Pages 1834-1846.e4
Chapter 119 – Techniques of liver replacement, Pages 1847-1869.e1
Chapter 120 – Early and late complications of liver transplantation, Pages 1870-1878.e2
Chapter 121 – Whole Organ pancreas and pancreatic islet transplantation, Pages 1879-1887.e1
Chapter 122 – Injuries to the liver and biliary tract, Pages 1889-1897.e2
Chapter 123 – Pancreatic and duodenal injuries, Pages 1898-1904.e2
Chapter 124 – Aneurysm and arteriovenous fistula of the liver and pancreatic vasculature, Pages 1905-1914.e2
Chapter 125 – Hemobilia and bilhemia, Pages 1915-1927.e2