Seat No.: _____ Enrolment No.
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GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM - SEMESTER–5 EXAMINATION – WINTER -2023
Subject Code: BP501TT Date: 02/12/2023
Subject Name: Medicinal Chemistry II
Time:10.30 a.m. to 1.30 p.m. Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1 (a) Classify Diuretic agents in detail with brief mechanism of action of each class. 06
(b) Write in detail about drugs used in Congestive Heart Failure 05
(c) Give details of Drugs used in Hyperthyroidism. 05
Q.2 (a) What are Local Anesthetic agents? Write SAR of Local Anesthetics. 06
(b) Write in detail about Contraceptives. 05
(c) Describe about Antimetabolites and Plant products for Cancer treatment. 05
Q.3 (a) Write in detail about chemistry of Histamine. Give details of different receptors 06
of Histamine
(b) Explain about Nomenclature and stereochemistry of steroids. 05
(c) Give detail account on various corticosteroids. 05
Q.4 (a) Define antihypertensive agents with its classification in detail. 06
(b) Describe about Antibiotics anticancer with mode of action. 05
(c) Give synthesis (1) Benzocaine (2) Warfarine 05
Q.5 (a) Classify Anti histaminic agents in detail with structure. 06
(b) Describe about Coagulants in detail. 05
(c) Write in detail about anticoagulant agents. 05
Q. 6 (a) What are Antiarrhythmic agents? Classify them in detail. 06
(b) Give detail accounts of Antianginal agents. 05
(c) Write in detail about Antisecretory agents. 05
Q.7 (a) Classify Antidiabetic agents in detail. 06
(b) Give synthesis of (1) Mechlorethamine (2) Acetazolamide 05
(c) Write a note on H2-receptor antagonist. 05
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