Body fluid
Body fluids, bodily fluids, or biofluids are liquids within the human body.[1] In lean healthy adult
men, the total body water is about 60% (60–67%) of the total body weight; it is usually slightly
lower in women (52-55%).[2][3] The exact percentage of fluid relative to body weight is inversely
proportional to the percentage of body fat. A lean 70 kg (160 pound) man, for example, has
about 42 (42–47) liters of water in his body.
Intracellular and extracellular fluid compartments. The extracellular fluid compartment is further subdivided into the
interstitial fluid and the intravascular fluid compartments.
The total body of water is divided into fluid compartments,[1] between the intracellular fluid (ICF)
compartment (also called space, or volume) and the extracellular fluid (ECF) compartment
(space, volume) in a two-to-one ratio: 28 (28–32) liters are inside cells and 14 (14–15) liters are
outside cells.
The ECF compartment is divided into the interstitial fluid volume – the fluid outside both the
cells and the blood vessels – and the intravascular volume (also called the vascular volume and
blood plasma volume) – the fluid inside the blood vessels – in a three-to-one ratio: the interstitial
fluid volume is about 12 liters, the vascular volume is about 4 liters.
The interstitial fluid compartment is divided into the lymphatic fluid compartment – about 2/3's,
or 8 (6–10) liters; the transcellular fluid compartment is the remaining 1/3, or about 4 liters.[4]
The vascular volume is divided into the venous volume and the arterial volume; and the arterial
volume has a conceptually useful but unmeasurable subcompartment called the effective
arterial blood volume.[5]
Compartments by location
intracellular fluid (ICF), which consist of cytosol and fluids in the cell nucleus[6]
Extracellular fluid
Intravascular fluid (blood plasma)
Interstitial fluid
Lymphatic fluid (sometimes included in interstitial fluid)
Transcellular fluid
Health
Body fluid is the term most often used in medical and health contexts. Modern medical, public
health, and personal hygiene practices treat body fluids as potentially unclean. This is because
they can be vectors for infectious diseases, such as sexually transmitted diseases or blood-
borne diseases. Universal precautions and safer sex practices try to avoid exchanges of body
fluids. Body fluids can be analyzed in medical laboratory in order to find microbes, inflammation,
cancers, etc.
Clinical samples