BC30™ Introduction
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The gut microbiota
The gut microbiota is the population of
trillions of bacteria and microorganisms
in your intestines that are key to your
health and wellbeing.
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Probiotics defined
“Live microorganisms which when
administered in adequate amounts
confer a health benefit on the host.”
Live microbes in the diet
Must provide a health benefit to the consumer
Must be delivered to the digestive tract in efficacious quantities
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Forms of bacterial probiotics
While common vegetative probiotics strains are fragile, spore-forming strains like Bacillus coagulans can
survive most manufacturing processes, allowing for innovation beyond the dairy case.
Vegetative Cell Spore-Forming Cell
• Vegetative cells are very fragile and vulnerable BC30 germinates with the right:
to the low gastric pH and bile salts. • Temperature (30°C)
• Susceptible to the rigors of most manufacturing • Water Activity (greater than 0.7)
processes and shelf life of most food products. • Substrate (food source)
• Generally, need to be refrigerated to survive
shelf life of finished product.
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BC30 formulation flexibility
BC30 survives these BC30’s limitations:
processes:
• UHT/UP*
• Powder blending • Retort
• Baking • Hot, high moisture and long
• HTST Pasteurization hold times
• HPP Pasteurization • Shelf stable liquid beverages*
• Boiling *possible with available cap/straw technology
• Microwave
• Freezing
• Shelf Stable Products with
Water Activity (Aw) < 0.75
• And more…
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BC30 survives from manufacturer to stomach
U.S. Manufacturing Site Shipping Customer Warehouse,
Ambient Storage,
Up to 3-year Shelf Life
Survivability
The Whole Story
Through Digestion On the Shelf Manufacturer Processing
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BC30 Possibilities
In Food
• Hot & Cold Cereal
• Baked Goods – cookies, muffins, pancakes
• Sweet & Savory Snacks
• Sports & Nutritional Bars
• Yogurt & Dairy Products
• Fruit Purees & Cups
In Beverages (cold chain only)
• Smoothies
• Juices
• Teas and Coffees
• Enhanced Waters
• Children’s Beverages
• Milk & Other Dairy Products
• Nutritional Beverages
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How does BC30 work?
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FACT 1
Health benefits are
strain-specific
Peer reviewed,
Just as CFU counts are strain published studies are
specific, so are probiotic benefits.
required to support the
Many probiotics have digestive benefits of a particular
benefits, but some strains have probiotic strain.
specialized benefits such as
immune support, heart health,
mood balance or protein utilization.
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Understanding strain specificity
Japanese car » Bacterial group » Lactic acid bacteria
Honda » Bacterial genus » Bacillus
Accord » Bacterial species » Bacillus coagulans
EX-L V-6 Sedan » Bacterial strain » Bacillus coagulans GBI-30, 6086
Every bacteria strain has its own strain-specific genomic and phenotypic
characteristics.
• NO TWO strains of bacteria are identical.
• Safety and clinical data from one strain cannot be used to support the
safety and efficacy of another strain.
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FACT 2
More CFUs aren‘t
always better
There is no “ideal” number of CFUs.
• Probiotics are measured in CFUs
(Colony Forming Units)
• Probiotic organisms must be alive to
be grown and counted.
• Probiotic organisms are unique – as
are the levels needed for benefit
efficacy and safety.
• Peer reviewed, published studies on
the specific strain are required to
support inclusion levels – 100 Billion
CFU is not necessarily better or more
efficacious than 1 Billion CFU.
Colony
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BC30 Clinical
Research
©©
Kerry 2020
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BC30 clinical research
Science-Backed Benefits A Broad Range of Consumers
BC30 published clinical, pre-clinical, and biomarker
Research supports the ability of research includes a wide range of consumers:
BC30 to help support the following
benefits:
Active Consumers General Population
• Digestive Health @
1 Billion CFU/daily Older Adults Children
• Protein Absorption @
1 Billion CFU/Daily The research includes a variety of studies:
• Immune Health @
500 M CFU/daily Modulation of
Abdominal Distress IBS Symptoms
Gut Microbiome
• Probiotic / Live Cultures @
500 M CFU / daily Immune
Digestive Health
Exercise Stress Health
Biomarkers
Biomarkers
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BC30 clinical research highlights
Focus Published Study Type Topline Results First Author, Journal Name, Year
BC30 helps normalize bowel
Digestive Health Abdominal Distress Study Clinical Digestive Health Kalman, BMC Gastroenterology, 2009
function in adults experiencing IBS.
BC30 reduces occasional digestive discomfort,
IBS Symptoms Dolin, Methods & Findings in Experimental
Digestive Health Clinical Digestive Health including reported abdominal pain
Study & Clinical Pharmacology, 2009
and bloating.
IBS Symptoms
Digestive Health Clinical Digestive Health BC30 supports the digestive health of adults. Hun, Postgraduate Medicine, 2009
Study - II
School Aged Children Clinical Digestive and BC30 reduces gastrointestinal (GI) Anaya-Loyola, Food Research
Digestive Health
in Mexico Part 1 Immune Health discomfort in children. International, 2019
School Aged Children Clinical Digestive and BC30 helps support the Anaya-Loyola, Food Research
Immune Health
in Mexico Part 2 Immune Health immune health of children. International, 2019
Biomarkers of BC30 may support the
Immune Health Viral Challenge Model (In Vitro) Baron, Postgraduate Medicine, 2009
Immune Health immune response in adults.
Kimmel, Methods & Findings in
Biomarkers of
Immune Health Viral Challenge Model II (In Vitro) BC30 may support the immune response. Experimental & Clinical Pharmacology,
Immune Health
2010
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BC30 clinical research highlights
Focus Published Study Type Topline Results First Author, Journal Name, Year
BC30 improves milk protein
Protein Absorption Milk Protein Digestion Clinical Protein Absorption Stecker, Nutrition & Metabolism, 2020
absorption in humans.
BC30 improves the recovery response
Gepner, Journal of Applied Physiology,
Protein Absorption Soldier Exercise Stress Clinical Protein Absorption from intense training when combined with
2017
nutritional supplementation.
BC30 increases recovery and decreases
Protein Absorption Recovery from Exercise Stress Clinical Protein Absorption Jaeger, PeerJ, 2016
soreness after intense exercise in active adults.
Preclinical Model
Protein Absorption Milk Protein Digestion (In Vitro) BC30 may improve milk protein digestion. Maathius, Beneficial Microbes, 2010
Protein Absorption
Preclinical Model BC30 may improve
Protein Absorption Plant-Based Protein Digestion (In Vitro) Keller, Beneficial Microbes, 2017
Protein Absorption digestion of plant-based proteins.
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BC30 Approvals
Regulatory Approvals in 70+ countries globally.
Customer Need
A probiotic ingredient that provides
science-backed benefits and
consumer transparency.
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BC30™ Branding
CONFIDENTIAL AND PROPRIETARY
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Brand building
with consumers
The BC30 brand continues to grow globally. BC30 is available in
more than 1,000 products worldwide in a variety of functional
food & beverage applications.
• Many product packages prominently feature the BC30 brand
& logo, building recognition globally.
• Branded ingredients like BC30 provide consumers a clear
point of reference when browsing shelves, delivering on
transparency and building trust.
• Website and social media platforms provide opportunities
to connect with and educate consumers.
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BC30 Brand Tools
Collateral (White Papers, Infographics)
Websites
[Link]
Social Media Sites
BC30 Probiotic Facebook
BC30 Probiotic Twitter
BC30 Probiotic LinkedIn
BC30 Probiotic Instagram
Blogs & Expert Insights Articles
BC30 Expert Insights
QR code
BC30 Consumer facing
Influencer Campaign
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Beverages- Product Examples
BC30
is featured
in over 1,000
products
globally
Food and beverage brands globally have
selected BC30 as the high-quality, premium
probiotic ingredient to deliver safe and
proven benefits to their consumers.
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More Product Examples…
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Other Beverage launches
Powder Beverages Shakes & Meal Replacement Tea & Coffee
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Food launches GanedenBC30
is featured
Snacks, bakery, confectionery Meals,inDairy,
over 1,000 Food Service/
products Convenient stores
globally
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BC30 into tea bag application in Italy
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[Link]
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Bc3 into mineral water application in the USA
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[Link]
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Thank You!
CONFIDENTIAL AND PROPRIETARY
Kerry Group Confidential © 2022