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Br J Ophthalmol: first published as 10.1136/bjophthalmol-2019-314354 on 17 April 2019. Downloaded from http://bjo.bmj.com/ on 22 April 2019 by guest. Protected by copyright.
doi:10.1136/bjophthalmol-2019-314354 Keith Barton, James Chodosh,‍ ‍ Jost B Jonas‍ ‍ , Editors in chief

Prior non-irradiative focal therapies do Repeatability of vessel density of the long-wavelength fluorophores
not compromise the efficacy of delayed measurements using optical coherence improves the accuracy and reliability of
episcleral plaque brachytherapy in tomography angiography in retinal assessments.
retinoblastoma (see page 699) diseases (see page 704)
In a retrospective study of 50 patients, the In patients with retinal disease, vessel Optic nerve edema at high altitude occurs
lack of prior diode or green laser therapy density measurements by optical coher- independent of acute mountain sickness
was predictive of an increased risk of treat- ence tomography angiography demon- (see page 692)
ment failure. The use of non-irradiative strated a high degree of repeatability. The Swelling of the optic nerve at high alti-
focal therapy was not predictive of time factors affecting such repeatability were tude occurs independent of acute moun-
to treatment failure. Visual outcomes and BCVA, signal strength, central macular tain sickness. The increase of optic nerve
toxicity were favourable, but the incidence thickness, and GC-IPL thickness. sheath diameter and development of optic
of cataracts following brachytherapy often disc oedema are not directly related.
requires intervention. Relationship between vessel density and
visual field sensitivity in glaucomatous
eyes with high myopia (see page 585) Five-year visual outcomes after
Clinical features of paediatric uveitis at anti-VEGF therapy with or without
a tertiary referral centre in Sao Paulo, Peripapillary vessel density measured by
photodynamic therapy for polypoidal
Brazil (see page 636) optical coherence tomography angiog- choroidal vasculopathy (see page 617)
In this retrospective study of paediatric raphy shows a significantly better associ- Anti-vascular endothelial growth factor
uveitis in a tertiary centre in Sao Paulo ation with the visual field mean sensitivity therapy alone and combination with
(SP), Brazil, juvenile idiopathic arthritis than the peripapillary retinal nerve fibre photodynamic therapy for polypoidal
was the systemic condition most often layer thickness in glaucomatous eyes with choroidal vasculopathy yields similar 5
associated with uveitis. Preservation of high myopia. year visual outcomes and retinal structural
visual acuity was associated with early changes; however, macular atrophy tends
referral and adequate management. Morphological and topographical
appearance of microaneurysms on optical to be more frequent with combination
coherence tomography angiography (see treatment.
Cycloplegic refraction by 1%
cyclopentolate in young adults: is it the page 630)
gold standard? The Anyang University Diabetic microaneurysms were classified Characteristics of patients with
Students Eye Study (AUSES) (see page into different morphological subtypes neovascular age-related macular
654) on optical coherence tomography angi- degeneration who are non-responders to
In a school-based study of young Chinese intravitreal aflibercept (see page 623)
ography. These subtypes were associated
adults, lack of cycloplegia resulted in a The frequency of aflibercept-nonrespon-
with clinical characteristics of microaneu-
significant misclassification of myopia, sive AMD was 5.2%. The non-responders
rysms, in terms of leakage on fluorescein
hypermetropia and emmetropia. were significantly associated with
angiography, and retinal thickening on
choroidal vascular hyperpermeability and
optical coherence tomography.
Quantitative retinal microvasculature lower frequency of subretinal hyper-re-
in children using swept-source optical The relationship of intercapillary area flective materials. Aflibercept-nonre-
coherence tomography: The Hong Kong to visual acuity in diabetes mellitus: sponsive AMD was mostly treatable by
Children Eye Study (see page 672) an optical coherence tomography photodynamic therapy or ranibizumab.
Age, gender, body mass index, axial angiography study (see page 604)
length, central macular thickness and Increased intercapillary area measured LVP keratoprosthesis: anatomical and
OCT-A quality score were associated from optical coherence tomography functional outcomes in bilateral end-stage
with quantitative retinal microvasculature angiography, describing enlargement of corneal blindness (see page 592)
measured from optical coherence tomog- capillary rarefaction or closure at macular The clinical outcomes of the novel LVP
raphy-angiography in a population-based area, was independently associated with keratoprosthesis were favourable, both in
sample of Chinese school children. poor visual acuity and worsening diabetic terms of anatomical retention and visual
retinopathy. recovery, in children and adults with
Evaluation of a deep learning image completely dry eyes and severe blinding
assessment system for detecting severe Comparison of short-wavelength blue- end-stage keratopathy.
retinopathy of prematurity? (see page light autofluorescence and conventional
580) blue-light autofluorescence in geographic Outcomes of ultrathin descemet stripping
This deep learning image assessment atrophy (see page 610) automated endothelial keratoplasty (UT-
system accurately identified clinically The increased excitation of short-wave- DSAEK) performed in eyes with failure of
significant retinopathy of prematurity length fluorophores was associated with primary descemet membrane endothelial
based only on posterior pole fundus photo- the ability of the FAF, using 450 nm, keratoplasty (DMEK) (see page 599)
graphs. This has potential implications for to identify and quantify geographic Ultrathin DSAEK provided excellent
screening and to improve diagnostic accu- atrophy lesions. However, enhancement visual rehabilitation for patients following
racy of retinopathy of prematurity. the primary failure of DMEK
Br J Ophthalmol May 2019 Vol 103 No 5 i
 At a glance

Br J Ophthalmol: first published as 10.1136/bjophthalmol-2019-314354 on 17 April 2019. Downloaded from http://bjo.bmj.com/ on 22 April 2019 by guest. Protected by copyright.
Intraocular bleeding in patients managed Surgical outcomes of a new affordable CMV endotheliitis and subsequently graft
with novel oral anticoagulation (NOAC) non-valved glaucoma drainage device and failure.
and traditional anticoagulation: a ahmed glaucoma valve: comparison in
network meta-analysis and systematic the first year (see page 659) Squamous cell carcinoma in the
review (see page 641) The new, low cost non-valved drainage anophthalmic socket - A series of 4 cases
Meta-analysis of Phase III trials of NOACs device, Aurolab Aqueous Drainage with HPV-16 profiling (see page 680)
vs warfarin for atrial fibrillation or venous Implant, was observed to have a higher Squamous Cell Carcinoma can rarely
thromboembolism shows Edoxaban is success rate and comparable safety when occur in the conjunctiva of anophthalmic
significantly associated with a reduction in compared with the Ahmed Glaucoma sockets. The exact cause is unclear, but it
the rate of intraocular haemorrhage. Valve. is likely that human papillomavirus may
play a role.
Randomised, prospective clinical trial Prevalence and clinical consequences
of platelet-rich plasma injection in the of cytomegalovirus dna in the aqueous Functional and aesthetic outcomes of
management of severe dry eye (see page humor and corneal transplants (see page eyelid skin grafting in facial nerve palsy
648) 666) (see page 692)
Injections of Platelet Rich Plasma into CMV DNA was detected in 10.0% Periocular skin grafts in facial nerve palsy
the lacrimal gland of patients with aqueous, 26.7% recipient corneas, and are effective in improving lagophthalmos
severe dry eye perform well, in terms of 20.0% donor corneas obtained during and periorbital symmetry where skin
safety as well as and improvement of all keratoplasty from 30 patients. Four contraction exists. Graft appearance takes
measured parameters in tear parameters patients with CMV positivity in aqueous/ at least 6 months to start looking natural
.measurement recipient developed postkeratoplasty and blend with eyelid skin.

ii Br J Ophthalmol May 2019 Vol 103 No 5