2 - Short Stature (Final)
2 - Short Stature (Final)
clinics
Compiled by-
Med Cdt Arnab Patra
Med Cdt Daanish
E3 batch
HOPI :
The child was apparently asymptomatic till 3 years of age when his/her mother noticed that the child
was not growing adequately as per his/her peer groups.
It was associated with inward bowing of the legs and thinning of limbs.
1. h/o headache, seizures, loss of consciousness, nausea, vomiting and visual field defects (rule out
CNS causes - infections, Craniopharyngioma, hypothalamus/pituitary space occupying lesion)
3. h/o breathlessness, difficulty in breathing, cough, blood in sputum (haemoptysis) and Wheezing
(Respiratory causes - Asthma, Pneumonia, TB)
4. h/o Abdominal distension, yellowish discoloration of sclera and skin (jaundice), blood in vomitus
(haematemesis), passage of dark colored, tarry, sticky stool (melena) - suspect chronic liver disease
leading to portal hypertension
h/o easy bruisabilty, loss of appetite
5. h/o chronic diarrhoea, large volume greasy stools (Malabsorption syndromes like IBD, Celiac
disease and Tropical sprue)
6. h/o polyuria, blood in urine, flank pain, decreased urine output ( suspect renal involvement -
Chronic Kidney Disease, Renal Tubular Acidosis)
7. h/o easy fatiguabilty, difficulty in breathing, pale face, blood transfusion - chronic Anaemia 8. h/o
recurrent blood transfusion - Thalassemia
Family history :
h/o short stature in parents (familial)
h/o delayed onset of puberty in parents (constitutional growth delay)
h/o Hypothyroidism or any Endocrine disorders in family
h/o AIDS in parents
Antenatal and Birth history :
Antepartum :
Any fever with rash (TORCH infections)
Abnormal serology or viral markers
Any exposure to teratogenic drugs, radiation
Multifoetal gestation - leads to growth retardation
Maternal conditions like Hypertension (PIH), Hypothyroidism
Intrapartum:
h/o low birth weight (Small for Gestational Age child)
Term or Preterm birth
Any h/o Neonatal hypoglycemia or Neonatal jaundice or micropenis (in boys) - suspect
Hypopituitarism
(Hypoglycemia - Neonate developed seizures 24 - 48 hours after birth for which he/she was given i.v.
glucose)
Developmental history :
Delayed motor development milestones (Cerebral palsy)
Nutritional history :
h/o inadequate dietary intake - suspect Undernutrition
h/o Breastfeeding exclusively for 6 months - if not suspect chronic infections
Immunization history :
Inadequate immunization - suspect infections
Plot them onto the WHO MGRS chart and find in which percentile/Z-score the child lies
US:LS
Normal 1.7 at birth, 1.3 at 3 years, 1.1 at 6 years, 1 at 10 years and 0.9 in adults Disproportionate
body
US Upper segment(vertebra) anomalies like Spondyloepiphyseal dysplasia and vertebral defects lead
to decreased US:LS
LS Lower segment(upper limb and lower limb) defects like Rickets, Achondroplasia, Osteogenesis
imperfecta and Epiphyseal/Metaphyseal/Diaphyseal dysplasias lead to increased US:LS
Hypothyroidism presents as both proportionate as well as disproportionate short stature
Dysmorphic features
Mongolian slant, epicanthus folds - Down's syndrome Webbed neck, widely spaced nipples -
Turner's syndrome
Moon like face with buffalo hump, Central obesity, Abdominal striae - Cushing's syndrome Spider
naevi, dilated umbilical veins - Chronic liver disease
3 year old male child, 1st child of a non-consanguineous marriage, presented with complaints
of not gaining adequate height as per his peer groups and there is inward bowing of the legs
for the last 9 months
No family history of short stature or delayed puberty
On examination the child was found to have reduced height for age below 3rd centile which
indicates stunting
There is genu varum deformity in the lower limb
Diagnosis :
Pathological short stature most likely due to Rickets
Bone
age !
growth velocity
!
Height
For infants (who cannot stand without support) - measure length using infantometer
For children who can stand without support - measure height using staediometer
After measuring the height, plot on the height for age chart
For <= 5 years : use WHO growth charts (gives result in SD)
For > 5 - 18 years : use IAP growth charts (gives results in percentiles)
Now we can also use combined IAP WHO growth charts for 0 - 18 years (gives results in
percentiles)
Plot the mid parental height at 18 years on the height for age chart and mark it with a ↔
Plot it at 18 years with vertical arrows and then trace them backwards along the growth curves
till 0 years and then shade the area between the 2 curves.
If the child's height is < - 3 SD, but still within the target height range it means it is a familial
short stature
If the child's height is less than the target height range but is between - 2 SD and - 3 SD it is
most likely a Constitutional short stature
3
95 95
90 90
0
85 85
-2
Length (cm)
80 80
-3
75 75
70 70
65 65
60 60
Months 6 7 8 9 10 11 1 2 3 4 5 6 7 8 9 10 11
1 year 2 years
Age (completed months and years)
WHO Child Growth Standards
Height-for-age GIRLS
2 to 5 years (z-scores)
125 125
3
120 120
2
115 115
110 0 110
105 105
Height (cm)
100 -2 100
95 -3 95
90 90
85 85
80 80
Months 2 4 6 8 10 2 4 6 8 10 2 4 6 8 10
2 years 3 years 4 years 5 years
Age (completed months and years)
WHO Child Growth Standards
Length-for-age BOYS
6 months to 2 years (z-scores)
100 100
3
95 95
2
90 90
85 85
Length (cm)
-2
80 80
-3
75 75
70 70
65 65
Months 6 7 8 9 10 11 1 2 3 4 5 6 7 8 9 10 11
1 year 2 years
Age (completed months and years)
WHO Child Growth Standards
Height-for-age BOYS
2 to 5 years (z-scores)
125 125
3
120 120
2
115 115
110 0 110
105 105
Height (cm)
100
-2 100
-3
95 95
90 90
85 85
80 80
Months 2 4 6 8 10 2 4 6 8 10 2 4 6 8 10
2 years 3 years 4 years 5 years
Age (completed months and years)
WHO Child Growth Standards
Weight
For newborns, keep a warm cloth on the weighing scale and reset it to 0 g
Remove all the child's clothing and place the child on the warm cloth and measure the weight
After birth, the baby loses around 10% of the birth weight in the first 7-10 days due to loss of
extracellular fluid
Thereafter the child starts regaining weight when adequately breastfed
Weech's formula for estimated weight as per weight of the child as per age for chikdren > 2
years : (Age × 2) + 8 kg
If Weight for age < - 2 SD - UNDERWEIGHT (can be due to both Acute and Chronic
Malnutrition)
Weight-for-age GIRLS
Birth to 2 years (z-scores)
17 3 17
16 16
15 2 15
14 14
13 13
12 12
0
11 11
Weight (kg)
10 10
9 -2 9
8 -3 8
7 7
6 6
5 5
4 4
3 3
2 2
Months 1 2 3 4 5 6 7 8 9 10 11 1 2 3 4 5 6 7 8 9 10 11
Birth 1 year 2 years
Age (completed months and years)
WHO Child Growth Standards
Weight-for-age GIRLS
2 to 5 years (z-scores)
30 30
3
29 29
28 28
27 27
26 26
25 2 25
24 24
23 23
22 22
21 21
Weight (kg)
20 20
19 19
18 0 18
17 17
16 16
15 15
14 14
-2
13 13
12 -3 12
11 11
10 10
9 9
8 8
7 7
Months 2 4 6 8 10 2 4 6 8 10 2 4 6 8 10
2 years 3 years 4 years 5 years
Age (completed months and years)
WHO Child Growth Standards
Weight-for-age BOYS
Birth to 2 years (z-scores)
17 3 17
16 16
15
2 15
14 14
13 13
12 0 12
11 11
Weight (kg)
10 10
-2
9 9
-3
8 8
7 7
6 6
5 5
4 4
3 3
2 2
Months 1 2 3 4 5 6 7 8 9 10 11 1 2 3 4 5 6 7 8 9 10 11
Birth 1 year 2 years
Age (completed months and years)
WHO Child Growth Standards
Weight-for-age BOYS
2 to 5 years (z-scores)
28 28
3
27 27
26 26
25 25
24 2 24
23 23
22 22
21 21
20 20
Weight (kg)
19 19
0
18 18
17 17
16 16
15 15
14 -2 14
13 13
-3
12 12
11 11
10 10
9 9
8 8
Months 2 4 6 8 10 2 4 6 8 10 2 4 6 8 10
2 years 3 years 4 years 5 years
Age (completed months and years)
WHO Child Growth Standards
Plot the weight on the Weight for Age charts
For <= 5 years : use WHO growth charts (gives result in SD)
For > 5 - 18 years : use IAP growth charts (gives results in percentiles)
Now we can also use combined IAP WHO growth charts for 0 - 18 years (gives results in
percentiles
For < 5 years, calculate the weight for height percentile from the WHO growth charts
For > 5 years, calculate the BMI = (weight in kg/(height in m)²) and Plot on the BMI for age IAP
charts
If Weight for Height/ BMI for age < - 2 SD - WASTING (Acute Malnutrition)
If Weight for Height / BMI for age < - 3 SD - SEVERE WASTING
Weight-for-length GIRLS
Birth to 2 years (z-scores)
3
24 24
22
2 22
20
1 20
0
18 18
-1
16 16
-2
Weight (kg)
14 -3 14
12 12
10 10
8 8
6 6
4 4
2 2
Length (cm)
WHO Child Growth Standards
Weight-for-Height GIRLS
2 to 5 years (z-scores)
32 32
3
30 30
28 2 28
26 26
1
24 24
0
22 22
-1
Weight (kg)
20 20
-2
18 18
-3
16 16
14 14
12 12
10 10
8 8
6 6
Height (cm)
WHO Child Growth Standards
Weight-for-length BOYS
Birth to 2 years (z-scores)
24 3 24
22 2 22
20 1 20
18
0 18
-1
16 16
-2
Weight (kg)
14
-3 14
12 12
10 10
8 8
6 6
4 4
2 2
Length (cm)
WHO Child Growth Standards
Weight-for-height BOYS
2 to 5 years (z-scores)
30 3 30
28 28
2
26 26
1
24 24
0
22 22
-1
20 20
Weight (kg)
-2
18 18
-3
16 16
14 14
12 12
10 10
8 8
6 6
Height (cm)
WHO Child Growth Standards
Occipitofrontal circumference or Head circumference
Place the tape over the occiput posteriorly and Superior orbital ridge anteriorly
Keep the metallic end towards the side to avoid injury to the child
Take 3 readings and calculate the average of the readings which gives the occipitofrontal
circumference or Head circumference of the baby
Maximum increase I Head circumference takes place in the first 2 years to accommodate for the
growing brain as brain development tales place mostly in the first 2 years of life
54 3 54
2
52 52
1
50 0 50
48
-1 48
-2
Head circumference (cm)
46 46
-3
44 44
42 42
40 40
38 38
36 36
34 34
32 32
30 30
Months 2 4 6 8 10 2 4 6 8 10 2 4 6 8 10 2 4 6 8 10 2 4 6 8 10
Birth 1 year 2 years 3 years 4 years 5 years
Age (completed months and years)
WHO Child Growth Standards
Head circumference-for-age BOYS
Birth to 5 years (z-scores)
3
54 54
2
52 1 52
0
50 50
-1
48 48
-2
Head circumference (cm)
46 -3 46
44 44
42 42
40 40
38 38
36 36
34 34
32 32
30 30
Months 2 4 6 8 10 2 4 6 8 10 2 4 6 8 10 2 4 6 8 10 2 4 6 8 10
Birth 1 year 2 years 3 years 4 years 5 years
Age (completed months and years)
WHO Child Growth Standards
Chest circumference
Take 3 readings and calculate the average of the readings which is the chest circumference
By 1 year of age, HC = CC
Mark the Mid point between the Acromion process of the shoulder and the Olecranon process of
the elbow
At the midpoint measure the circumference by cross tape method and take the average of 3
readings as the Mid upper arm circumference (MUAC)
23 23
3
22 22
21 21
2
20 20
19 19
Arm circumference (cm)
1
18 18
17 17
0
16 16
-1
15 15
14 -2 14
13 13
-3
12 12
11 11
10 10
Months 3 6 9 3 6 9 3 6 9 3 6 9 3 6 9
1 year 2 years 3 years 4 years 5 years
Age (completed months and years)
WHO Child Growth Standards
Arm circumference-for-age BOYS
3 months to 5 years (z-scores)
22 22
3
21 21
20 20
2
19 19
Arm circumference (cm)
18 1 18
17 17
0
16 16
15 -1 15
14 -2 14
13 13
-3
12 12
11 11
Months 3 6 9 3 6 9 3 6 9 3 6 9 3 6 9
1 year 2 years 3 years 4 years 5 years
Age (completed months and years)
WHO Child Growth Standards
Arm span
Make the child stand straight with his/her back towards you
Ask him/her to touch the tip of the middle finger on one side wall
Mark the point of the tip of the other middle finger
Measure the distance between the wall and the marked point and that will give the arm span
Increased Arm span for that age indicates probable MARFAN'S SYNDROME
Arm span is a measure of the lower segment, hence may be shortened in case of Rickets,
Osteogenesis imperfecta
Lower segment (Appendicular skeleton) - Measure from the lower border of the pubic symphysis
to the heel and then upper segment = height - lower segment
Upper segment (Axial skeleton) - Measure from the vertex to the pubic symphysis and then the
lower segment = height - upper segment
At birth, US : LS is 1.9
At 1 year it is 1.7
At 3 years It is 1.3
At 7-9 years It is 1.1
At 10 years It is 1 US = LS
After 10 years, it is 0.9
8
ANTHROPOMETRY
Height
Head circumference
Chest circumference
Head
Face
Eyes
Ears
Nose
Mouth & oral cavity
Neck
Chest
Abdomen
External genitalia
Skin
Extremities
Back & spine
SMR stage (if required)
Developmental age assessment(if required):
10
SYSTEMIC EXAMINATION‐RESPIRATORY SYSTEM
• Upper RT:
• Lower RT:
•Inspection
Flaring of nose: trachea: Shape of chest:
Accessory muscles: Chest wall retraction:
Movement of chest: Apex beat:
Bony cage:
•Palpation:
To confirm inspection findings: Tenderness:
Tactile vocal fremitus: Friction rub:
•Percussion:
•Auscultation:
Breath sounds
Adventitious sounds
Vocal resonance
11
CARDIO VASCULAR SYSTEM
• Inspection:
Pulse: BP: JVP:
Precordium: Apex beat: Pulsations:
• Palpation
Confirm inspectory findings: Apex beat:
Heart sounds:
Parasternal heave: Epigastric
pulsation : Thrill:
• Percussion:
• Auscultation:
Heart sounds: Added sounds:
Murmurs:
12
GIT EXAMINATION
Upper GIT :
Per abdomen:
• Inspection:
Shape: Movement:
Visible peristalsis: Pulsation/veins:
Hernial orifices: Ext. genitalia:
• Palpation:
Confirm inspection findings
Tender: Liver: Spleen:
Kidneys: Bladder: Any other mass:
Renal angle: Ext. genitalia:
13
GIT EXAMINATION
Percussion:
Fluid thrill:
Auscultation:
BS
Bruit
Memory: Speech:
Delusions/Hallucinations:
15
• Cranial nerve examination:
Right Left
• Motor system:
Upper Limb Lower Limb
Right Left Right Left
Bulk
Tone
Power
16
Reflexes Right Left
Superficial reflex
Deep tendon reflex
‐Biceps
‐Triceps
‐Supinator
‐Knee jerk
‐Ankle jerk
‐Clonus
Primitive reflex (if required)
17
Abnormal movements:
Hemiballismus: Dystonia:
Any other:
18
Sensory system:
Upper Limb Lower Limb
R L R L
Touch
Pain
Temperature
Pressure
Position
Vibration
Cortical sensation
19
Cerebellar signs:
Nystagmus: Speech: Finger nose test:
20
Signs of meningeal irritation:
• Neck rigidity:
• Kernig’s sign:
• Brudzinski’s sign‐ neck/leg sign
Skull &spine
• Mac Ewan’s sign
• Cranial bruit/carotid bruit
• Transillumination of skull
• Tenderness over spine, gibbus, tuft of hair,
kyphoscoliosis
21
Differential diagnosis:
Investigation:
Treatment:
Follow up:
22