IQE ACADEMY OF HIGHER EDUCATION AND RESEARCH, BELAGAVI.

Aceredltect A. [ Declared as Deemed-to-be University u/s 3 of the UGC Act, 1956 ]

Grade by NAAc 3,.. C cle Placed ID 'A' Cate O b MHRD Go

MBBS PHASE - II
(CBME)
T·line: 3 Hours DEGREE EXAMINATION - MARCH 2023
Max.Marks: 100
MICROBIOLOGY
PAPER- I

Q.P. Code: A0ll

Answers should be specific to the Questions asked.
Draw neat, labeled diagrams wherever necessary.
All the questions are compulsory.
Question Number
\ c,,1'"9 0' Marks
1. M.C.Q. . (fr (j 20 X 1 = 20
LONG ESSAY QUESTIONS: 2 X 10=20
2. There is an epidemic of diarrhea that has occurred in remote village and
all the sufferers are presented with ·passing of-Rice· ter·stool since-2-3 •
hours. As a medical officer how are you gomg to a) refer the cljpjca1
~aw;u,es b) W.~~~-.!~ _your diagnosis and describe the pathogenesi~ ~) Write in
detail about the lab diagnosis d) Enumerate the causes for diarrhea~_1
3. Define and classify Hypersensitivity. Discuss in detail Type I
Hypersensitivity. 11

SHORT ESSAY QUESTIONS: 9 X 5 = 45 ~.: · •:_ :

4. Write a note on Bacterial growth curve with the help of a diagram.
5. Describe the factors predisposing to microbial pathogenicity.
6. Illustrate the sequence of appearance of HBV antigens and antibodies in a chronic
active Hepatitis case.
7. Enumerate Herpes viruses and add a note on laboratory diagnosis of the cutaneous
manifestations of Herpes simplex.
8. Write a short note on cutaneous filariasis.
9. Describe the structure of lgG with a neat labeled diagram and write its functions.
IO. Describe NACO (National AIDS Control Organization) strategies forHIV testing.
11. Describe the laboratory diagnosis of Malaria.
11'2.) In an elderly male the blood smear show~ Hypochromic microcytic an~mia. On
V urine microscopy, pus cells more than 10/HPF, RBCs present, eggs measuring 110-
170 µ .long by 40-70 µ wide and bearing a CO_!lSQicuous. ttaminaLspine...was o.h.~erved. ,.I,,
a) What is the probable parasite responsible for anemia? --) {.j(;J. fv'fY'\.'r
b) Describe the life cycle of the parasite. • • (/ ( fi,J"' 11)1"W" H
I •

SHORT ANSWER QUESTIONS: 5 X 3 = 15

13. Define selective media with two examples. Pi •IP' p4~ ltdi,-,
14. Vaccines for Typhoid fever. Wl )W.~ ¢#-J !1#€,
15.
Draw the colored and 1agram of Trichuris trichura ova. ,.l~ '°' 1 Mlf } ~
Y,Ground itc . , ·--. -~ ,
)}I Define atopy and give two examples for the same. 1M ,A¢}tw 61/IWI I / fC
1

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MU LT IPL E CHOIC.E QU ES TIO
2023 Max. Ma rks : 25 Marks
Course: MBBS Phase-II (CBME), March
AOll 30 Minutes
Subject: Microbiology Paper-I, QP Code: Tim e:

.
Instructions: . . .
r options.
Each question is followed by fou e circle m the OMR Sheet provided .
on and darken !he appr~pnat
Pick up the single best optimar .
k. No negative marking
Each question carries one
ther apy
1. Who is known as father of Chemo
(B) Paul Ehr lich _,,
(A) Aiexander Fleming
(C) Robert Koch (D) Joseph Lister

2. Most common stain used for iden

(A) Lactophenol cotton bl ue '
tifying mould is
(B) Grams_Stain ' '
(D) ZN stam

"
(C) Albert Stain
- . . .
item when
ng sys tem , which of the following is classified as a semi-critical
3. Under the Spauldi n/disinfection?
considering methods for sterilizatio ... -i
•(B) Syringe · · , ,. . . . • . ., ,
• .• ,, •:
• • ••
i • .•

(A) Surgical instrum\!nt • (D) Blood pressure cuff

.. '
, '
(C) En do sco ~
is tenned as
organism multiplies exponentially
4. An animal host i~ which pathogenic (B) Transmitting ;J
(A) Reservoir (D) Definitive
(C) Am plif ier. ,,
5. Gaffky-Eberth bacillus is
(A) E.c oli (B) Proteus
(C) Sal mo nel la., - (D) Shigella
l
is
6. The gene coding for core of HN I
(A )G ag , (B) Pol
(C) Env (D) Tat

ncy
7. Duri..ng the period of clinical late
ctab le . ged
(A) HIV js not dete (B) CD4 cell count remains unchan
to others org ans ,
(C) Virus cannot be transmitted (D) Virus is present in lympho id

ently there is an upsurge in

8.
e tak en up a rese arc h pro ject to screen a village for Malaria. Rec
You hav area. Ideal investigation would be
cases of con.finned Malaria in that (B) Rapid antigen detection
n _.,
(A) Peripheral smear examinatio ation
chain reac tion (D) Quantitative buffy-coat examin
(C) Pol ym eras e
9. ch route
Rotavirus vaccine is given by whi
(A) Intramuscu lar (B) Intravenous
(C) Ora l_,, , (D) Subcutaneous

ic egg s is bile stained and operculated?

I 0. Which of the following parasit (B) N. am eri can s/'
(A) A duodenale (D) D. latum
(q S. stercoralis
Cholera stools EXCEPT
I I. AU are transport media for (B) Fluid thioglycollate
(A) Cary-Blair (D) Alkaline peptone water /
(C) Venkatraman Ramakrishnan
~~....::...
...i:.~~---
- - - ·~ ; , = - c,"~===-
==~==~~= = --

• on1·
r. d pois
. ed w1'th ,oo ng atlter consumption of fried rice
II ciat ·
12. Wh1'ch ofth e ,o owing bacteriwn is asso
c-.
(B) C. perfringens
(A) S. aureus (D) B. cer eus ,
(C) E. fecalis
caused by
1 Black dot tinea capitis is mainly (B) T. tonsurans
(A) E. floccosum (D) T. rubrum ,
(C) M. canis
for
14. Genn tube test is diagnostic (B) Candida albicans . ~
(A) Candida glabrata (D) Coccidioides imm1t1s
(C) Cryptococuus th
cs OPD with slapped cheek appearance rash. What is e
ght to pediatri
I 5. A 7 month old baby was brou
most probable diagnosis?
(B) Rubella
(A) Measels (D) Erythema infectiousum r
(C) Molluscum contagiosum

16. Chiclero ulcer is caused by (B) Leishmania braziliensis com

plex
ple x/
(A) Leishmania Mexicana com (D) Leishmania chagas i
(C) Leishma nia peruviana

s) artificial-passive immunity? •
g confer(
•• i-9:- Which-of-the followin (B) 'MM R vaccine
(A) Hepatitis B vaccine l antibodies
unoglobulin / (D) Cross placental transfer of materna
(C) Hepatitis B imm

defect in
18. DiGeorge syndrome is due to (B) B cell
(A) Tce ll ,
r, (D) Complement
(C) Phagocyte
the same day care centre. If the
of Jaundice occurs in several young children who afterid
- 19. An outbreak t likely cause?
ch one of the following is the mos
outbreak was caused by a virus, whi (B) Hepatitis B Virus
(A) Hepatitis A Vir us ~ (D) Hepatitis D Virus
(C) Hepatitis C Virus

20. All are sporicidal EXCEPT (B) Gluteraldehyde

(A) Lysol (D) Methanol -,,,,,,,
(C) Ethylene oxide
 KLE ACADEMY OF !!~!~!~~!,;iyTION ANDuocRESEARCH
l
, BELAG.AVJ
~~~~~~~:_s~[~Dec---;;;;si~~E-:iii""__ __
u1, 3 of th• Act. t 956
•
3,. ·cle __.P_l•c_,d_ln_'A_'.,.c;;,;1te:O:o::lry~b~lot,-.
AccrtdltedA•Gradeb ·NAAC
MBBS PHASE- JI
- . (CBME)
DEGREE EXAMINATION - MARCH 2023

Time: 3 Hours Max. Marks: 1Oo

MICROBIOLOGY
PAPER-II
I
[ Q.P. Code: A012
I
Answers should be specific to the Questions asked.
Draw neat, labeled diagrams wherever necessary. I
All the questions are compulsory.
Question Number Marks
l. M.C.Q.
LONG ESSAY QUESTIONS:
. 1 respiratory tract infections. a) Describe the geno ic variati
20 X t :::: 20
2 X lO::::2o
'
I
2. Enwnerate vrra ons
· influenza viruses. b) Discuss the laboratory d'1agnos1s o ov1•
- .
(2+3+5) l
J .. ~~e ar old, male was brought to the ~ospital for fe~er,_ stiff
vomiting for two days. On admission, his CSF exammat1on showe
neck, headache and •• (2+3+S) I
d low glucose,

'
high protein and polymorphonuclear leuc~cytes counts <300/m
m3. Indian ink .
preparation of CSF sh?wed: caps~ated,:buddmg Yf@§1&ells. ~
a) What is the etiological d1agnos1s? - h ..... -~ _ /J r·' J(id I
f u{;IJCtCfJ...,{ ) ,.
b) Describe the pathogenesis of this condition.
• I
, c) Discuss its laboratory diagnosis.
SHORT ESSAY QUESTIONS: I
4. Discuss the specific (treponemal) tests for the diagnosis of Syphilis. 9 X 5 == 45 . I
5. Discuss the pathogenesis of UTI (Urinary Tract Infection).
6. What is CAUTI? How do you collect the sample in suspec
ted CAUTI and prevent t
this infection?
r A 60 yr old male patient underwent abdominal surgery. After
5 days of surgery
patient started having vUowjsb discba&0e tcaro ab<Jpmjpa) §UUJte.
Explain how you
could have prevented the infection?
8. Describe the role of Clicical Microbiologist in HIC~Hospi
tal Infection Control
Committee).
9. Write a brief note on micro-organisms causing opportunistic
infection in malignancy.
10. Describe the tests to investigate a suspected case of Diphtheria.
1I. Compare the Wild Virus types (WPV) and Vaccine Derived
Polio Virus (VDPV).
12. Describe the pathogenesis and laboratory diagnosis ot_Weil's
disease. ,
SHORT ANSWER QUESTIONS: .. ,1,.•, 1
L)
Lt,(,~J,_.." 1 • 5X3= 15
13. A patient with tuberculosis comes to OPD, what is the
mode of transmission of
infection to others from this patient? How to prevent th?j:°smissi
14. Draw neat labelled diagram ofTrichomonas vaginali• __ on? P
15. Newly built Tertiary care hospital of a metro city is in the '
process of undergoing
NABH developing hospital infection control policies. Write the guidel
ines to prevent .
Needle prick injuries.
16. Describe Mc Farlands reaction and its significance.
17. Name three organism causing Encephalitis. .._

****

j.
 KLE ACADEMY OF HIGHER EDUCATION AND RESEAR CH, BELAGAVI.
Act, 19S6]
[ Declared as Deemed-to-be University u/s 3 of the UGC
Pl•ced In •A• Cate1ory by MoE (Gol)
_!«:reditecl A+ Grade by NAAC (3,. Cycle)

MULTIPLE CHOICE QUESTIONS

Course: MBBS Phase-II (CBME), March 2023 Max. Marks: 20 Marks
Subject: Time: 30 Minutes
Microbiology Paper-O, QP Code: A012

Instructions:
Each question is followed by four options. .
Pick up the single best option and darken the appropriate circle in the OMR Sheet provided.
Each question carries one mark. No negative marking.

1. Rabies is identified by
(A) Guarneri bodies· (B) Negri bodies , '
(C) Cowdry A bodies (D) Paschen body

2. A case of cystic fibrosis, developed exacerbation of bouts of cough. The sputum submitted grew a greenish
blue pigment producing gram negative bacilli. The organism is,
(A) Staphylcoccus aureus (B) Chromobacterium violaceum
(C) Pseudomonas aeruginosa , ' (D) Serratia marcescens

3. A patient with complaints of fever and dry cough, sore throat swab grew throat commensals on culture.
The condition of the patient worsened with elevated C-reactive protein, D-dimer. Now that you are
-s\lspecting SARS-CoV-2, which of the following is·true, ···• ... • • •
{A) A nasopharyngeal swab for antigen detection (B) Serum testing for presence of antibody
(C) An oro-nasopharyngeal swab for RT-PCV (D) Quarantine him for two weeks without
" investigating

• 4. Functional receptor for SARS-CoV-i is· •

(A)ACE2 _,,,,, (B) CD26
(C) BothA& B (D) CD4

5. How much bacillary load in sputum is required for an effective transmission ofM. tuberculosis
(A) 10 bacilli per ml (B) 100 bacilli/ml
(C) 1000 bacilli/ml -,, (D) 10000 bacilli/ ml

6. Characteristics of primary chancre

(A) Painless punched out ulcer (B) Painless ulcers with over hanging edges ,II'

(C) Painless ulcers with irregular raised edges (D) Painful punched out ulcer

7. Most Common cause of community-acquired urinary tract infection is

{A) E.coli_, (B) Proteus
(C) Pseudomonas (D) Klebsiella

of
8. In VAP (Ventilator Associated Pneumonia) patient as maintenance bundle care what is standard angle
degree to which head end of the bed should be elevated
{A) IO to 25 degrees (B) 30 to 45 de!,7fees /
(C) 40 to 55 degrees (D) 60 to 75 degrees

9. Following are ESKAPE pathogen EXCEPT

(A) Enterococcus faecium (B) Staphylococcus aureus
(C) Klebsiella pnuemoniae (D) Proteus vulgaris /

I0. Multiple painful ulcer is feature of

(A) Syphillis (B) Herpes /
(C) Chancroid {D) Donovanosis
..
. ..

. • entable by vaccine
11. Which of the followm_g STD ts prev (B) HIV .
(A) Hepatitis B_im:ectton""" (D) (]1ancro1d
(C) Herpes gemtahs
f h nd hygiene have been laid down by WH 0
12. How many moments o a. (B) 6
ws ~8
(C)7,
. . fT lasma goodii in Jmmuno compromised adult
13. Most common mamfestation oxop (B) Chorioretinitis °
(A) lymphad~~opathy (D) Encephalitis '1"
(C) Myocardths
. . h f . C from blood transfusion in India is currently
14. The risk of acquinng epa ltls (B) 0.02%,
(A) 0.1 % (D) 0.07%
(C) 0.05%
·stic infection that occurs in HIV-infected people is
15. The most common oppurtunl • . •
Which of the following is not an ESKAPE (A) Staphylococcal 1n ectton
pathogen (C) Staphylococcus aureus
(B) Enterococcus faecium
(E) Proteus mirabilis
(D) Streptococus.-,

16. \Vhich of the following is a superficial fung~ infection _ . . _ __,,., ..

(A) Favus • (B) Pityriasis versi~olor
(C) Tinea capitis (D) Chromomycos1s
1 • • ..... ,. • • - ••
.. ,,. • r • • • ' • l - ' • ··· ... ' • • .. • ... ·\ J. •• • • . ·'

with diminishe~ vision an~ neck s_tiffnes~: -~

f

17. ••A ~ddle aged wo1Il8Il, a regular swim~?r was

examination she was found to have keratitts and memngitis. She gave the history of usmg sell11soft contact
, lenses. Her CSF culture on axenic media showed microbial growth. Which organisms are common!
associated in such condition • y
(A) S. pneumoniae (B) M. tuberculosis . . . _ ....
(C) T. gondii. (D) Acanthamoeba sp.'

18. A child aged one year presented with signs of meningitis, the CSF showed pleomorphic gram negative
bacilli. On blood agar culture the organisms showed enhanced growth in presence ofX and V factors.
VJbat is the likely organism associated with this case? -
{A) H.influenzae , (B) E.coli
(C) B. pertusis (D) M.tuberculosis

19. Which of the following tests confirms the diagnosis of Leptospirosis?

(A) Culture of urine on EMJH media, Testing serum hy darkfield examination for the presence of
. Leptospira. . . . . . . .
{B) Test?1g serum by darkfield examination for the presence of Leptospires. ) (
(C) Testmg acute and convalescent phase sera for Anti-Leptospiral antibodies by microscopic
agglutination tes~
(D) Culture ofCSF on blood and chocolate agar.

20. Plague is transmitted by

(A) Rat flea~ (B) Soft tick
(C) Hard tick (D) Louse
• •.I• .- • '•
... •I• •,-