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Bhalla Tak

Bhallatak, or Semecarpus anacardium, is a medium-sized tree known for its medicinal properties and is used in traditional medicine to treat various ailments. The fruit contains anacardic acid and has anti-inflammatory, anti-microbial, and hepatoprotective activities, but can be toxic if ingested improperly, leading to severe gastrointestinal and skin reactions. Proper preparation and antidotes, such as Terminalia bellerica, are essential for mitigating toxicity effects.

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0% found this document useful (0 votes)
93 views60 pages

Bhalla Tak

Bhallatak, or Semecarpus anacardium, is a medium-sized tree known for its medicinal properties and is used in traditional medicine to treat various ailments. The fruit contains anacardic acid and has anti-inflammatory, anti-microbial, and hepatoprotective activities, but can be toxic if ingested improperly, leading to severe gastrointestinal and skin reactions. Proper preparation and antidotes, such as Terminalia bellerica, are essential for mitigating toxicity effects.

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BHALLATAK

• Botanical Name- Semecarpus anacardium Linn.


• Seme- Simeion- चिह्नित करिा या ट्रे स करिा- Marking Nut
• Carpus- Nut anacardium- दिल के आकार का निशाि वाला िट ।
• Family- Anacardiaceae (Amra kula)
• Synonyms-
• 1.तैल बीजं-तैल बीजस्या -Bhallataka fruit is oily
• 2.वातारर – वातिाशिारू -Bhallataka pacifies vata
• 3.वीरवक्ष
ृ - वीययवाि वक्ष
ृ – it is a sharp and potent plant.
• 4.अग्िीकृत- Bhallataka is warm in nature.
• 5.अरुष्कर
• 6.भिलावा
BHALLATAK
* िल्लातक उपववष वर्य में सह्ममभलत है।
* उपववष िल्लातक का उपयोर् चिककत्सीय
उद्िे श्य के भलए उचित शोधि के बाि ही ककया
जाता है ।
* िल्लातक को अधय वैद्य मािा जाता है, क्योंकक
इसका उपयोर् कई रोर्ों को ठीक करिे के भलए
ककया जाता है ।
* अर्र इसका उपयोर् शोधि के बाि और उचित
युह्क्त के साथ ककया जाए तो यह कई बीमाररयों
को ठीक करता है ।
EXTERNAL MORPHOLOGY OF SEMECARPUS
ANACARDIUM
Habit: Bhallataka is a medium-sized tree that grows up to 30-50 feet.
Bark- Bark of Bhallataka is gray and exudes an irritant secretion on
incising.
Leaves- Leaves of Bhallataka are simple, 30-60 cm long, 12-30 cm
broad, obovate to oblong, glabrous above, ashy gray or buff and
pubescent beneath, and developed on the tip of the branch, and
deciduous.
Inflorescence- compound panicle.
Flowers- Small, greenish-yellow, dioecious, with long flower stalk,
petals are 5- 6, stamens 5- 6, the ovary is rudimentary in male flowers
and superior in case of female flowers.
Fruit- Drupaceous nut, 2-3 cm long, heart-shaped, green when raw
and turn to black on ripening. Fruits are attached to a fleshy orange-
colored receptacle, which is edible.
Seeds- Pendulous.
• Fruit contains black, oily, and highly vesicant juice used
traditionally to mark the clothes.

Properties Bhallataka Properties


1. Rasa Katu,Tikta,Kashaya,Madhura
2. Guna Ushna, Laghu, Teekshna
3. Veerya Ushna
4. Vipaka Madhura
5. Karma Rasayana, Balya, Krimighna,
Shukrala
6. Dosha karma Kapha- vata hara, Pitta vardhaka
7. Amayika prayoga Gulma, Grahani, Arsha, Kushta
8. Dose 125 to 375 mg
CHEMICAL COMPOSITION OF BHALLATAK
1.Black corrosive juice of pericarp contains 90% of
anacardic acid and 10% of cardol (non-volatile alcohol).
2.Kernel of the nut contains catechol and anacardol
(mono hydroxy phenol).
3.Bhilawanol and anacardoside present in oil and
seeds.
4.Nicotinic acid, riboflavin, thiamine and essential
amino acid-arginine, histidine, isoleucine, leucine,
lysine, methionine, phenylalanine, threonine,
tryptophan and valine are present in fruit.
BHALLATAK SHODHANA

1. िल्लातक फल को बीि में से काटकर इह्ष्टका िूर्य


में रखा जाता है अथवा इह्ष्टका िर्ू य से घषयर् ककया
जाता है , तत्पश्िात उष्र् जल से प्रक्षाभलत ककया जाता
है ।

2. िल्लातक फल का िाररकेल जल में िोला यंत्र में


स्वेिि ककया जाता है ।
PHARMACOLOGICAL ACTIVITY

1. Anti-Oncogenic Activity

2.Anti-Inflammatory Activity

3.Anti-Microbial Activity

4.Anti-Arthritic Effect

5.Hypoglycaemic Activity
ASHUDDHA AVIDHI SEVANA JANYA DOSHA
1.If Ingested Orally
Burning sensation in mouth, throat, chest & epigastric region (upper GIT)
Blackish blister containing acrid serum
Excessive salivation, nausea & vomiting
Pain & cramps in abdomen (Entire)
Watery purgation, sometime with blood stains & mucus
Excessive thirst, Oligourea, Anurea

2.Application on Skin
Painful blackish blister containing acrid serum
Eczematous eruption with severe itching
Fever, painful micturation with brown urine

Fatal Dose :- Uncertain but considered to be 5- 10 gms, Seeds- 6-8 and Oil- 9-
10ml
Fatal period:- 12-24 hours.
ANTIDOTE

• The main antidote of Semecarpus anacardium is Terminalia


bellerica i.e Bibhitaka.
• Coconut oil will be a good antidote.
• Application of Meghanada Rasa (Juice of Amaranthus tricolor)
with-Navaneeta (Butter).
TREATMENT OF BHALLATAKA TOXICITY

• Bhallataka Shothahara Yoga - Local application of paste of Tila rubbed with


buffalo milk and mixed butter or local application of paste of Yasthimadhu and
Tila rubbed Shalapatra.

• Arushkara Shothaghna Lepa - Paste of Tila with goat milk and butter or Krishna
Mritika is used in Shotha caused by Bhallataka.

• Local Application - For quick relief of Bhallataka Shotha are as follows - Mixture
of Mehnad Swarasa.and butter or mixture of Devdaru, Sarshapa, Nagarmotha
and Navneeta or mixture of Navneeta, Tila Mishri and milk or Neema, Tila, Tila
Tail are boiled together and made concentrated to apply locally.
• When manifestation of toxicity obseved, medication of Bhallataka is stopped
and white albumen of coconu juice of leaves of Chincha given to eat. Externally
coconut oil, ghee, lead lotion is applied.
• The specific antidote for the toxicity of Bhallataka is Bibhitaka (terminalia
belerica). The decoction of powder preparation with fruit rind and bark of
terminalia belerica are effective for the sudden reactions and for systemic
effects. Drug that mitigate Pitta like milk and clarified butter and other drugs
with cold potency may also be used.
FORMULATIONS OF BHALLATAKA
1.भल्लातकादिमोिक . िैषज्य रत्िावली (प्लीहयकृत रोर्ाचधकार)

िल्लातकाियाजाजीर्ड ु ि
े सह मोिकः ।
सप्तरात्राह्निहनत्याशु प्लीहािमनतिारुर्म ् ।।
घटक द्रव्य
• शुद्ध िल्लातक 1 िार्
• हररतकी 1 िार्
• जीरक िूर्य 1 िार्
• र्ुड़ 6 िार्
• शुद्ध भिलावा, हरड़ और जीरा इिके समिार् र्ह ृ ीत िूर्य में द्ववर्र्
ु र्ड
ु भमला
कर एक माशे की मात्रा से मनिोष्र् िग्ु धािप
ु ाि के साथ सात दिि तक सेवि
करिे से अत्यनत बढ़ी हुई प्लीहा िष्ट हो जाती है ।
• मात्रा व अनपु ान - 1 gm , र्मय िग्ु ध से
काल - िोजि से पव ू य 7 दिि के भलए
उपयोग - प्लीहा, यकृत रोर्
पथ्य – लघु व नतक्त िोजि
अपथ्य – उष्र्, कटु, लवर् प्रधाि िोजि
PHARMACODYNAMICS OF BHALLATAKA MODAKA

• Bhallatak Modak depicts strong hepato protection against CCl4 induced liver
injuries in three consequent experimental studies. It brings significant
reduction in liver enzymes towards normalcy. Similarly, it not only arrests
necrosis and degeneration but also brings considerable regeneration of
hepatocytes.
• 1. Haritaki has shown choleretic hepatoprotective, and immune stimulant
properties.
• 2. Jiraka is well known forits antioxidant, hepatoprotective, anti-inflammatory,
and antimicrobial properties, in addition it is also used in and gastrointestinal
disorders. It has also been reported to be useful in jaundice and as a
hepatoprotective agent.
• 3. Guda is a major constituent of Bhallatak Modak. It is a powerful haematinic
and is valuable in the treatment of haemolytic jaundice and micro lytic
anaemia. The main focus of action of Bhallatak Modak in body is liver.
ACC. TO RASA’s PROPERTY
•The drug Bhallatak contains Katu, Tikta, kashaya rasa. Bhallatak contains
ushna and tikshan property because of those properties it is kaphvat shamak
and pit vardik.
•The drug Bhallatak modak contains Bhallatak, Haritaki, Jiraka, and Guda
collectively acts as tridoshahara, specially kaphahara.
•It causes agnideepana and pachana due to its katurasa and ushna and
teekshnagunas. It should be used as agnideepana in Kaphaja agnimandya.
•In Grahani, arsha, ajeerna, atisara, udara, gulma and krimis which are all
caused by agnimandya. Bhedana action of Bhallataka helps to overcome
vibandha, anaha, gulma, udara and to reduce the size of yakrit and pleeha
whenever there is their enlargement. It eliminates doshas accumulated in the
pakvashaya.
PHARMACOKINETICS OF BHALLATAKA MODAK
• 1.Absorption:The bioactive compounds from Haritaki (tannins, flavonoids),
Jiraka (thymol, cuminaldehyde), and Guda (iron, minerals) are absorbed
primarily in the small intestine.The formulation may enhance bile secretion,
aiding fat-soluble component absorption.
• 2. Distribution:The active constituents are likely distributed via the
bloodstream, with a high affinity for liver tissues due to the hepatotropic
nature of the herbs. Guda’s iron content contributes to hemoglobin
synthesis, aiding systemic circulation.
• 3. Metabolism:Metabolized primarily in the liver, where Haritaki’s and
Jiraka’s polyphenols undergo hepatic biotransformation, enhancing their
antioxidant and hepatoprotective effects. Guda provides essential nutrients
supporting liver function and red blood cell production.
• 4. Excretion:Metabolites are excreted through bile and urine.Jiraka’s
antimicrobial and digestive properties may also influence gut microbiota and
fecal excretion.
RESEARCH UPDATES

•Effect Of Bhallatak Modak in Ccl4 Induced Acutehepatotoxicityin Rats by


Harmeet kour.
This study showed Bhallatak Modak has shown potential hepatoprotective
activity against the CCl4 induced liver damage in animal model.
2. भल्लातक घत
ृ प्रथम - िैषज्यरत्िावली, र्ल्
ु म रोर्ाचधकार

िल्लातकािां द्ववपलं पञ्िमल ू ं पलोह्नमतम ् ।


साध्यं वविारीर्नधाढयमापोध्य सभललाढके ।।
पािावशेषे पत ू े व वपप्पलीं िार्रं विाम ् ।
ववडङ्र् सैनधवं दहड्डु यावशूकं ववडं शटीम ् ।।
चित्रकं मधुकं रास्िां वपष्ठवा कषयसमं भिषक् ।
प्रस्थत पयसो ित्त्वा घत ृ प्रस्थं ववपाियेत ् ।।
एतद्िल्लातकं िाम कफर्ल् ु महरं परम ् ।
प्लीहपाण्ड्वामयश्िासग्रहर्ीकासर्ल् ु मिुत ् ।।
घटक द्रव्य
• 1. शुद्ध िल्लातक 2 पल
• 2. शालपर्ी 1 पल
• 3. पष्ृ िपर्ी 1 पल
• 4. कंटकारी 1 पल
• 5. बह ृ ती 1 पल
• 6. र्ोक्षुर 1 पल
• 7. वविारीकंि 1 पल
• 8. वपप्पली 1 कषय
• 9. सैनधव 1 कषय
• 10. विा 1 कषय
• 11. िार्र 1 कषय
• 12. ववडंर् 1 कषय
• 13. शुद्ध दहंर्ु 1 कषय
• 14. यव क्षार 1 कषय
• 15. ववड लवर् 1 कषय
• 16. किूर 1 कषय
• 17. चित्रक 1 कषय
• 18. मुलेठी 1 कषय
• 19. रास्िा 1 कषय
• 20. र्ो घत ृ 1 आढ़क
• 21. र्ो िग्ु ध 1 आढ़क
• शुद्ध िल्लातकफल २ पल, लघु पञ्िमल ू (सररवि, वपठवि,
छोटी कटे री, बड़ी कटे री, र्ोखरू) के प्रत्येक द्रव्य एक-एक पल,
वविारीकनि १ पल लेकर सबको ओखली में कूटकर १ आढक (४
प्रस्थ = ४ सेर) जल में डालकर उबालें तया िैथाई शेष रहिे पर
छाि लेवें। कफर उस क्वाथ में वपप्पली सोंठ, विा, वायववडङ्र्,
सैनधव लवर्, शद् ु ध दहङ्र्,ु यवक्षार, ववडलवर्, किरू , चित्रक की
छाल, मल ु ेठी और रासिा प्रत्येक १-१ कषय लेकर कूटकर पत्थर
पर जल के साथ पीस कर कल्क बिाकर भमलावें तथा िग्ु ध और
घत ृ १-१ प्रस्थ िर भमलाकर यथाववचध घत ृ भसद्ध कर लेिा
िादहए। यह िल्लातक घत ृ कफर्ल् ु म, प्लीहवद्ृ चध, पाण्डुरोर्,
श्वास, संग्रहर्ी, कास और र्ल् ु मरोर् को िष्ट करता है ।

• मात्रा व अनप
ु ान - 6-12 gm, र्मय िग्ु ध से

• उपयोग - कफर्ल्
ु म, प्लीहवद्
ृ चध, पाण्डुरोर्, श्वास, संग्रहर्ी,
कास
• भल्लातकघत
ृ म ् (द्ववतीय) - िैषज्यरत्िावली, र्ल्
ु म रोर्ाचधकार

िल्लातकात्कल्ककषायपक्वसवपयः वपवेच्छकयरया ववभम्रमम ् ।


तद्रक्तर्ल्
ु मं ववनिहह्नत पीतंबलासर्ल्
ु मं मधुिा समेतम ्
।।

घटक द्रव्य
• शुद्ध िल्लातक कल्क
• शद्
ु ध िल्लातक क्वाथ
• र्ो घतृ
• शुद्ध िल्लातक फल कल्क, शुद्ध िल्लातक क्वाथ तथा घत ृ
लेकर इि तीिों को कलईयुक्त पात्र में डालकर यथाववचध घत ृ
भसद्ध कर लेिा िादहए। इस घत ृ को ६ माशे से १ तोले िर
तक लेकर शक्कर भमला कर सेवि करिे से रक्तर्ल् ु म िष्ट हो
जाता है तथा शहि के साथ भमच्रमत कर सेवि करिे से काफ
र्ल्
ु म हो जाता है ।।

• मात्रा व अनप
ु ान - 3-6 gm, र्मय िग्ु ध से

• उपयोग - कफज र्ल्


ु म

• काल- अवस्थािुसार
PHARMACODYNAMIC ACTION OF BHALLATAKA GHRITA

• 1. Digestive & Metabolic Actions: Pippali, Saindhav, Nagar (Shunthi), Vacha,


Vidanga, Chitraka, Yavakshar, Vida Lavana – Enhance digestion, improve
metabolism, and relieve bloating and indigestion. Shudhha Hingu – Acts as a
carminative and anti-flatulent.
• 2. Hepatoprotective & Detoxifying Actions:Sudhha Bhallataka, Mulethi,
Goghrita, Godugdha – Support liver function, protect hepatocytes, and aid
detoxification. Chitraka, Vidarikand – Help in liver regeneration and digestive
enzyme secretion.
• 3. Respiratory & Anti-inflammatory Actions: Shalparni, Prushnaparni, Kantakari,
Brahati, Rasna, Gokshura – Have bronchodilator, expectorant, and anti-
inflammatory properties, beneficial in respiratory disorders.
• 4. Diuretic & Rejuvenative Actions: Gokshura, Vidarikand, Goghrita, Godugdha
– Act as Rasayana (rejuvenators), nourish tissues, and support kidney function.
• 5. Antimicrobial & Immune-Modulating Actions: Vidanga, Kachura, Vacha –
Exhibit antimicrobial, antiparasitic, and immune-modulatory effects.+
PHARMACOKINETICS

• 1. Absorption: The bioactive compounds, including alkaloids, flavonoids, tannins,


glycosides, and essential oils, are absorbed in the small intestine. Pippali, Shunthi, and
Saindhav enhance bioavailability by improving digestion and intestinal permeability.
Goghrita (clarified butter) and Godugdha (cow’s milk) act as carriers (Yogavahi),
facilitating better absorption of fat-soluble components.
• 2. Distribution: The herbal constituents reach target organs via plasma proteins and
lipoprotein.
• Hepatotropic herbs (Sudhha Bhallataka, Mulethi, Chitraka, Vidarikand) concentrate in the
liver.
• Diuretics (Gokshura, Rasna) distribute more to the renal system, aiding kidney function.
• Respiratory herbs (Shalparni, Prushnaparni, Kantakari, Brahati) accumulate in lung
tissues, supporting respiratory health.
• 3. Metabolism: Primary metabolism occurs in the liver, where polyphenols, alkaloids, and
saponins undergo enzymatic biotransformation. Some essential oils and alkaloids are
metabolized in the intestines by gut microbiota. Ghee-based components (lipophilic
compounds) undergo slow metabolism, leading to prolonged effects.
• 4. Excretion: Metabolites are eliminated mainly via bile and urine. Water-soluble
metabolites are excreted through the kidneys (urine), while some components are
expelled through the gastrointestinal tract (feces). Respiratory herbs may also be partially
excreted through the lungs (exhalation of volatile oils and aromatic compounds).
RESEARCH UPDATES

• Although no research has been done on above mentioned


bhallataka ghritas but a research named Bhallatakadi Ghrita:
Development and evaluation with reference to Murcchana
and Shata-Dhauta process has been done by Sandesh R.
Wayal in PRIST university,Tamilnadu.
3.गड ु भल्लातकः (प्रथमश्चक्रित्तोक्तः) - िैषज्यरत्िावली, अशय
रोर्ाचधकार
• िल्लातकसहस्त्रे द्वे जलद्रोर्े ववपाियेत ् ।
पािशेषे रसे तह्स्मि ् पिेद् र्ड ु तुलां भिषक् ।।
िल्लातकसहस्राद्यधं नछत्त्वा तत्र प्रिापयेत ् ।
भसद्धेऽह्स्मह्स्त्रफलाव्योषयमािीमस् ु तसैनधवम ् ।।
कषाांशसंभमतं िद्यात ् त्वर्ेलापत्रकेशरम ् ।
खािे िह्ग्िबलापेक्षी प्रातरुत्थाय मािवः ।।
कुष्ठाशयः कामला मेहग्रहर्ीर्ल् ु मपाण्डुताः ।
हनयात्प्लीहोिरं कास-किभमरोर्िर्निराि ् ।।
र्डु िल्लातको नयेष ्रमेष्ठश्िाशोववकाररर्ाम ् ।।
घटक द्रव्य

• शुद्ध िल्लातक 2500 िर्


• र्ुड 5 Kg
• आमलकी 12 gms
• हरीतकी 12 gms
• वविीतकी 12 gms
• िार्र 12 gms
• वपप्पली 12 gms
• मरीि. 12 gms
• शुद्ध भिलावा २ हजार पाकाथय २ द्रोर् जल में पकािे और
ितुथाांश शेष रहिे पर उतार कर उसमें १ तुला र्ड ु डालकर
पकावै और उसी में ५०० शद् ु ध भिलावा टुकड़े-टुकड़े कर भमला
िे और जब अवलेह की िांनत होिे लर् जाये तब हरड,
आमला, बहे ड़ा, सोंठ, पीपर, मररि, अजवाइि, मोथा, सेंधा
िमक, िालिीिी, छोटी इलायिी, तेजपत्र और िार्केशर इि
सिी का िर् ू य १-१ कषय लेकर डाल िे वे।
• इसके सेवि से कुष्ठ, अशय, कामला, प्रमेह, ग्रहर्ी ,
र्ल्
ु म, पाण्डुता, प्लीह रोर्, उिररोर्, कास, किभमरोर् तथा
िर्निर िष्ट होता है । यह 'र्ड ु िल्लातक' अशय रोर् वालों के
भलए ्रमेष्ठ है ॥
• द्ववतीय गड
ु भल्लातक - िैषज्यरत्िावली, अशय रोर्ाचधकार

• िशमल ू ामतृ ा िार्ी श्विं ष्ट्रा चित्रकं शटी ।


िल्लातकसहस्रं ि पलांशं क्वाथयेद् बुधः ।।
पािशेषे जलढोर्े रसे तह्स्मि ् ववपाियेत ् ।
ित्त्वा र्डु तलु ामेकां लेहीित ू ं समद्
ु धरे त ् ।।
माक्षक्षकं वपप्पलीं तैलमौरुबक ू ञ्ि िापयेत ् ।
अशयः कासमि ु ावर्त्य पाण्डुतां शोधमेव ि ।।
कुडवं कुडवं िात्र त्वर्ेलामरीिं तथा ।
िाशयेद्वह्निसािं ि र्ड ु िल्लातकः स्मत ृ ः ।।
घटक द्रव्य
• शद् ु ध िल्लातक – 1000 िार्
• िशमल ू – 460 gms
• र्ड
ु ु िी – 46 gms
• र्ोक्षुर – 46 gms
• चित्रक - 46 gms
• किरू - 46 gms
• र्डु - 5 kgs
• मधु - 190 gms
• वपप्पली - 190 gms
• एरं ड तैल. 190 gms
• त्वक 190 gms
• एला - 190 gms
• मरीि - 190 gms
• िशमल ू , चर्लोय, िारङ्र्ी, र्ोखरू, चित्रकमलू और किरू प्रत्येक
१-१ पल, एवं शोचधत भिलावा १००, पाकाथय जल १ द्रोर्, शेष ४
प्रस्थ। इसी क्वाथ में रे ड़ी का तेल १ प्रस्थ, पुरािा र्ड़
ु १ तुला (५
सेर) भमला कर पुिः पाक करिा िादहये। र्ाढ़ा होिे पर उतार कर
उसमें पीपर, िालिीिी, छोटी इलायिी और मररि इि सबों का
िर्ू य १-१ कुडव भमलाकर (ककसी-ककसी के मत से भमभलत िर् ू य १
कुडव लेिा िादहये।) शीतल होिे पर शहि १ प्रस्थ भमला कर रख
िे िा िादहये। इसके सेवि से अशय, कास, उिावतय, पाण्डु, शोथ और
अह्ग्िमानय आदि रोर् िष्ट होते हैं ।
• मात्रा व अनुपान – 2-5 gm, र्ो िग्ु ध व जल
• उपयोग - अशय ,कास ,पाण्डु , शोथ ,मंिाह्ग्ि
• काल – प्रातः काल
• पथ्य – िग्ु ध , घतृ , शाभल
• अपथ्य आहार व ववहार – उष्र् आहार , आतप सेवि
PHARMACODYNAMICS

• Digestive Stimulation: The combination of Haritaki, Vibhitaki, Pippali,


and Maricha stimulates the digestive fire (Agni), ensuring regular bowel
movements. This reduces the chances of constipation, one of the
leading causes of piles, by facilitating smoother stool passage.
• Anti-inflammatory and Astringent Effects: Bhallataka, Amla, and
Haritaki have strong anti-inflammatory properties, which help reduce
the swelling and pain associated with hemorrhoids. The astringent
properties of these herbs help to tone the blood vessels and tighten the
rectal tissues, promoting faster healing.
• Detoxification: Ingredients like Gud (jaggery), Amla, Haritaki, and
Vibhitaki play an important role in detoxifying the body. They help
remove toxins (ama) from the digestive system, ensuring smooth
elimination of waste and preventing the formation of hemorrhoids.
• Healing of Hemorrhoidal Tissues: Shuddha Bhallataka, Gud, and Amla
help promote the regeneration of damaged tissues in the hemorrhoidal
region. They reduce bleeding, pain, and irritation caused by piles.
PHARMACOKINETICS
• Absorption:The formulation is absorbed primarily in the stomach and intestines.
Ginger and Pippali stimulate gastric juices and digestive enzymes, which
promote better absorption of fat-soluble and water-soluble compounds. Amla,
Haritaki, and Vibhitaki contribute to enhancing the bioavailability of the
formulation’s active compounds in the digestive tract.
• Distribution:The ingredients, particularly the bioactive compounds from
Bhallataka, Amla, and Gud, enter the bloodstream and are distributed to target
areas like the rectum and liver. Ginger and Pippali also enhance the circulation
of active compounds to areas where healing is required (such as hemorrhoidal
tissue).
• Metabolism: Haritaki, Amla, and Vibhitaki support the liver's detoxification
pathways, helping process and break down the active compounds. Bhallataka
and Pippali likely undergo transformation in the liver and intestines, facilitating
their biological effects. Herbs with Vata balancing properties such as Haritaki
ensure that the metabolism of the formulation proceeds smoothly without
aggravating digestive imbalances.
• Excretion: The final metabolic products of the formulation are excreted via urine
and feces. The detoxifying and mild laxative effects of Gud (Jaggery), Haritaki,
and Vibhitaki ensure that any accumulated toxins or waste products are
effectively eliminated from the body, supporting the body’s natural
detoxification process. This also helps prevent constipation, which is a major
aggravating factor in piles.
RESEARCH UPDATES

• No research has been done on bhallataka guda yet.


• भल्लातकाद्यं तैलम ्

िल्लातकाकयमररिैलव य र्ोर्त्मेि भसद्धं ववडङ्र्रजिीद्वयचित्रकैश्ि ।


स्यानमाकयवस्य ि रसेि निहह्नत तैलं िाडीं
कफानिलकृतामपिीव्रर्ांश्ि ।।

घटक द्रव्य
शुद्ध िल्लातक 1 part
अकय 1 part
मरीि 1 part
सैनधव 1 part
ववडंर् 1 part
हररद्रा 1 part
िारू हररद्रा 1 part
चित्रक 1 part
नतल तैल 4 सैर
बबल्व स्वरस 1 part
• िल्लातक फलमज्जा, आक की जड़, काली मररि, सैनधव
लवर्, वायववडङ्र्, हररद्रा, िारुहररद्रा और चित्रक में छाल इनहें
समाि प्रमार् में भमलाकर अथायत ् ढाई-ढाई तोले िर लेकर कूट
के जल के साथ पत्थर पर पीसकर कल्क बिा लेवें तथा
नतलतैल ८१ सेर और िांर्रे का स्वरस ८४ सेर लेकर के
सबको भमलाकर यथाववचध तैल पाक कर लेंर्े।
• लेपववचध से प्रनतदिि प्रयक्ु त करिे से यह तैल कफ और वायु
से उत्पनि िाडीव्रर्, अपिी आदि व्रर् को िष्ट कर िे त है ॥

• उपयोग - िाड़ी व्रर् , अपिी


PHARMACODYNAMICS
• 1. Anti-inflammatory Action: Several ingredients such as Haridra, Daru
Haridra, Maricha, and Chitrak work synergistically to reduce the inflammation
around the wound. This helps to reduce pain, swelling, and discomfort while
promoting the healing of the tissue and blood vessels (Nadis).
• 2. Antimicrobial and Detoxifying Action: Ingredients like Arka, Vidanga,
Shuddha Bhallataka, and Haridra have strong antimicrobial and detoxifying
properties. These herbs help to control and eliminate any bacterial or
microbial infection that may be complicating the wound. By reducing the
microbial load, the formulation helps in preventing further infection and
promoting faster tissue regeneration.
• 3. Promoting Circulation and Tissue Regeneration: Maricha, Chitrak, and
Til Tail stimulate circulation in the affected area, improving the delivery of
oxygen and nutrients necessary for tissue repair. This promotes faster healing
of the damaged tissues and blood vessels (Nadis) involved in the wound.
• 4. Astringent and Wound Closure: Bilva Swaras and Saindhava provide
astringent effects that help tighten the tissues, promote wound closure, and
prevent further discharge, making them crucial in healing chronic wounds
such as Nadi Vran.
• 5. Carrier Action: Til Tail (Sesame Oil) acts as a carrier for the other
ingredients, ensuring that the active compounds are effectively delivered to
the wound site. It also nourishes and soothes the affected area, preventing
dryness and promoting smooth tissue regeneration.
PHARMACOKINETICS
• 1. Absorption:
• Skin Penetration: The oil formulation is applied directly to the affected
area, allowing for the active ingredients to be absorbed through the
skin and into the subcutaneous tissues. The lipid nature of sesame oil
(Til Tail) enhances the permeability of the skin, facilitating the
absorption of both hydrophilic and lipophilic compounds.
• Absorption Mechanism: Active ingredients like Haridra (Turmeric),
Daru Haridra, Chitrak, and Shuddha Bhallataka are absorbed
transdermally, and once they reach the dermal layer, they begin to
exert their pharmacological effects. The oil base helps to carry these
compounds deeper into the tissues by enhancing the solubility of the
herbs in the oil medium.
• Enhancement by Sesame Oil: Til Tail (Sesame Oil) is a natural carrier
and is well-known for its ability to improve the absorption of other
herbs. It acts as an emollient, making the skin more permeable and
allowing the active compounds to reach deeper tissues, including
blood vessels, muscles, and connective tissues, especially around the
wound area.
• 2. Distribution:
• Local Tissue Action: Once absorbed through the skin, the
active ingredients are distributed locally in the tissues around the
wound site. They are primarily concentrated in the affected area,
where they exert their anti-inflammatory, antimicrobial, and
wound-healing effects.
• Blood Circulation: Some ingredients, such as Maricha (Black
Pepper) and Chitrak, help stimulate local blood circulation. This
enhanced circulation facilitates the distribution of the active
compounds to surrounding tissues and ensures that the wound
healing process is supported by improved oxygen and nutrient
delivery to the wound area.
• Lymphatic and Vascular Systems: While the primary action is
local, the absorption of some compounds into the bloodstream
through capillaries near the skin may lead to low-level systemic
distribution, particularly for detoxifying and anti-inflammatory
ingredients like Vidanga and Haridra, which can also work on a
systemic level to reduce body-wide inflammation and toxins.
• 3. Metabolism:
• Local Metabolism: Once absorbed, the active ingredients
in the formulation undergo metabolic processes primarily
within the local tissues, where enzymes and cell receptors
play a role in activating certain compounds. For example,
Curcumin from Haridra (Turmeric) may undergo enzymatic
metabolism within the local tissues, contributing to its anti-
inflammatory and antioxidant effects.
• Hepatic Metabolism: In some cases, after being absorbed
into the bloodstream, ingredients may undergo first-pass
metabolism in the liver, where they are metabolized into
more active or water-soluble forms. However, the primary
therapeutic effect occurs at the site of application, and
systemic metabolism is limited, as the formulation is meant to
work topically.
• 4. Excretion:
• Sweat glands: The compounds may be excreted via
sweat, especially if they are water-soluble.
• Liver and kidneys: If the compounds enter the
bloodstream and undergo liver metabolism, their metabolites
can be excreted through the kidneys in the urine, though this
would be a secondary effect.
• Local Tissue Clearance: In the case of Shuddha Bhallataka
and other detoxifying herbs, their metabolites may be cleared
by the local immune cells or lymphatic drainage in the tissue.
RESEARCH UPDATES

• Although no research has been done on above mentioned


bhallataka taila but a research named EVALUATION OF SHELF
LIFE OF BHALLATAKA TAILA (OIL) has been done by Anu
Ruhilaa, Pramod R. Yadava, Galib Ra and Pradeep K. Prajapati.
• 5. भल्लातकावलेहो बह
ृ द् (यो. र.)- िैषज्यरत्िावली, अशय
रोर्ाचधकार

• सप ु क्विल्लातफलानि समयर् ् द्ववधा ववधायाढकसंभमतानि ।


ववपाच्य तोयेि ितुर्र् ुय ेि ितुथश य ेषे व्यपिीय तानि ।।
पुिः पिेत्क्षीरितुर्र्
ु य े ि घत ृ ांशयुक्तेि घिं यथा स्यात ् ।
भसतोपला षोडशभिः पलैश्िववमध्यय संस्थाप्य दििानि सप्त ।।
ततः प्रयोज्याह्ग्िबलेि मात्रांजयेद्ववकारािखखलाि ् र्ि ु ोत्थाि ् ।
किाः सि ु ीला घिकुह्ञ्िताग्राः स्यस् ु तार्थययदृह्ष्टश्ि
शशाङ्ककाह्नतः ।।
जवो हयािां बलमर्त् ु मं िस्वरो मयूरस्य हुताशिीह्प्तः ।
स्त्रीवल्लित्वं ववववधप्रिावोिीरोर्ता द्ववबत्रशतायरु े व ।।
ि िानिपािे पररहाययमह्स्त ि िातपे िाध्वनि मैथि ु े ि ।
प्रयोर्काले सकलामयािांराजाचधराजश्ि रसायिािाम ् ।।
घटक द्रव्य

• शद् ु ध िल्लातक 1 आढ़क


• जल 4 आढ़क
• घतृ
• शकयरा
• र्ोिग्ु ध
• सन ु िर पके हुये भिलावा के फलों को शुद्ध करिे के बाि िो
टुकड़े करके उि सबों को १ आढक लेकर उसे िौर्ि ु े जल में
पकाकर ितथ ु ाांश जल शेष रहिे पर उतार ले और उसमें
िौर्ि ु ा िध
ू डालकर एवं घत ृ िी डालकर पकावे जब लेह की
िांनत र्ाढ़ा हो जाय तब उसमें भम्रमी १६ पल भमलाकर ७ दिि
तक पड़ा रहिे िे । उसके बाि अह्ग्िबलािुसार मात्रा का निर्यय
कर प्रयोर् करिे से सिी प्रकार के अशय िष्ट होते हैं। तथा
इसके सेवि से बाल काले, घिे तथा घघ ु रु ाले होते हैं। और
र्रुड के समाि दृह्ष्ट और िनद्रमा के समाि मख ु की काह्नत,
घोड़ों के समाि वेर् और उर्त्म बल, मयूर का सा स्वर,
जठराह्ग्िका प्रिीपि, संिोंर्शह्क्त बढ़िे से स्त्रीवल्लिता,
िीरोर्ता, २-३ सौ वषय तक की िीघय आयु होती है । इसके
सेविकाल में अनि-पाि में ककसी प्रकार का बनधि िहीं है ।
धपू या रास्ता िलिा और मैथि ु इिका निषेध िहीं है । सवय
रोर्ों को िरू करिे के भलए रसायिों में यह सवय्रमष्े ठ हे ॥
• मात्रा व अनप ु ान – 5-10 gm , शकयरा व र्ोिग्ु ध
• उपयोग – अशय , वष्ृ य, बल्य
PHARMACODYNAMICS

• Anti-inflammatory: Reduces swelling and inflammation of the


hemorrhoidal tissues.
• Analgesic: Provides pain relief through its soothing and
cooling effects.
• Astringent: Tightens and tones the tissue, reducing bleeding
and promoting healing.
• Lubricating and Laxative: Softens stool and eases bowel
movements to prevent further strain on the hemorrhoidal
veins.
• Nourishing: Supports the regeneration and healing of the
damaged tissue, ensuring faster recovery.
• Cooling: Relieves burning sensations and irritation in the anal
region.
PHARMACOKINETICS

• • Absorption: Active compounds are absorbed primarily through


the small intestine, enhanced by the presence of ghee and milk,
which increase bioavailability, especially for fat-soluble
components.
• • Distribution: The compounds circulate through the
bloodstream, with a focus on the local action in the rectal and anal
tissues.
• • Metabolism: The active compounds are metabolized by the
liver, with fat-soluble compounds being processed for local tissue
action and some for systemic circulation.
• • Excretion: Water-soluble metabolites are excreted via the
urine, and fat-soluble metabolites are primarily excreted via the
feces or in minor amounts through sweat.
• • Duration of Action: The formulation provides sustained relief
from hemorrhoidal symptoms, with cumulative effects over time
due to the nourishing and anti-inflammatory actions.
RESEARCH UPDATES

• 1. standardization of bhallataka avaleha by harshal J.shinde


( M.D. RS&BK , Vishwakarma ayurved infertility & research
centre Mumbai) .
• 2. To study antimicrobial activity of standardized bhallataka
avaleha by harshal J.shinde ( M.D. RS&BK , Vishwakarma
ayurved infertility & research centre Mumbai).
• 6. भल्लातकादि लेप- िैषज्य रत्िावली , कुष्ठ रोर्ाचधकार

िल्लातकद्वीवपसध ु ाकयमल
ू ं र्ञ्
ु जाफलत्र्यूषर्शङ्खिूर्मय ्।
तत्ु थं सकुष्ठं लवर्ानि पञ्ि-क्षारद्वयं लाङ्र्भलकाञ्ि
पक्त्वा ।।
स्िन ु यकयिग्ु धे घिमायसस्थ शलाकया तद्वविधीत
लेपम ्।
कुष्ठे ककलासे नतलकालके ि सवेषु िि ु ायमसु िमयकीले
।।
घटक द्रव्य
• शुद्ध िल्लातक - 1 part
• चित्रक - 1 part
• स्िूही - 1 part
• अकय - 1 part
• र्ुंजा - 1 part
• िार्र - 1 part
• वपप्पली - 1 part
• मरीि - 1 part
• शंख िस्म - 1 part
• तुत्थ - 1 part
• कुष्ठ - 1 part
• सैनधव लवर् - 1 part
• ववड लवर् - 1 part
• सामुद्र लवर् - 1 part
• सोवियल लवर् - 1 part
• औद्भिि लवर् - 1 part
• सज्जी क्षार - 1 part
• यव क्षार - 1 part
• लांर्ुली - 1 part
• भिलावा फल, द्वीपी (चित्रकमल ू छाल), थह ू र की जड़, आक
की जड़, र्ञ्
ु जाफल (चिरम)ू , सोंठ, मररि, वपप्पली, शङ्खिस्म,
िीलतुत्थ, कूठ, पांिो लवर्, स्वह्जयक्षार, यवक्षार, और कभलहारी
की जड़ इिमें से प्रत्येक को एक-एक तोले िर लेकर िूखर्यत
करके कड़ाही में डालकर समस्त भमभलत िर् ू य से िौर्ि
ु े थह
ू र
और आक (भमभलत) के िग्ु ध के साथ पाक करिा िादहए।
• लोहे की शलाका को इस लेप से भलप्त करके कुष्ठ, ककलास,
नतलकालक, सब प्रकार के अशय और िमयकील पर प्रनतदिि लेप
लर्ािे से वे िष्ट हो जाते हैं ।
PHARMACODYNAMICS
• Anti-inflammatory: Most of the ingredients, including Pippali,
Maricha, and Chitraka, reduce inflammation in the skin, alleviating
redness, swelling, and pain associated with Kushta.
• Antimicrobial: Ingredients like Arka, Gunja, and Tuttha, with their
antimicrobial properties, help fight skin infections caused by bacteria,
fungi, or other pathogens.
• Detoxifying: Many of the herbs and salts like Snuhi, Shankha Bhasma,
and Vid Lavana are effective in detoxifying the skin, removing toxins,
and purging the body of impurities that contribute to chronic skin
conditions.
• Wound healing: Bhallataka and other healing herbs promote the
regeneration of damaged skin and assist in the healing of ulcers and
lesions that are commonly seen in Kushta.
• Circulation improvement: Ingredients like Nagar and Pippali enhance
circulation, ensuring that the skin receives adequate nourishment,
which helps in healing and rejuvenation.
• Balancing the Doshas: The combination of these herbs and salts works
to balance the Vata, Pitta, and Kapha doshas, which are thought to be
involved in the pathogenesis of Kushta.
PHARMACOKINETICS
• Absorption:
• • Topical Application: When the mask is applied to the skin, the active
compounds from the ingredients must first pass through the stratum
corneum (the outermost layer of skin) to enter deeper skin layers.
• Lipophilic (fat-soluble) Compounds: Some ingredients in the mask,
such as Bhallataka, Chitrak, and Pippali, contain lipophilic compounds that
may be better absorbed through the skin if the mask is left on for a longer
period. Lipids in the formulation (possibly from oils or ghee used in the
preparation) help these fat-soluble compounds penetrate the skin more
effectively.
• Hydrophilic (water-soluble) Compounds: Ingredients like Shankha
Bhasma, Sodium Chlorides (like Saindhava Lavana, Samudra Lavana), Sajjī
Kṣāra, and Yava Kṣāra may be more water-soluble and could have a
localized effect by interacting with skin cells on the surface or in the
superficial dermis (epidermis).
• Enhancers of Absorption: Some ingredients may act as penetration
enhancers, such as Snuhi (Euphorbia), which has a cauterizing effect and
can help in increasing permeability of the skin, making it easier for other
compounds to penetrate. Chitrak (Plumbago zeylanica) also has a role in
stimulating blood circulation, which can enhance the absorption of other
active compounds.
• Distribution:
• • Local Action on Skin: The majority of the active ingredients, such as
Bhallataka, Chitrak, Pippali, and Shankha Bhasma, are likely to act locally
at the site of application, targeting inflammation, skin ulcers, and
infections.
• Anti-inflammatory and Healing: Bhallataka and Chitrak have well-
known anti-inflammatory and wound-healing properties, which may
promote the regeneration of affected skin in Kushtha disease. These
compounds will be primarily localized in the area where the mask is
applied, reducing inflammation and encouraging tissue repair.
• Antimicrobial: Ingredients like Pippali (Piper longum), Mṛtyunjaya (a
plant used in traditional formulations), and Nagara (Zingiber officinale)
contribute antibacterial and antifungal properties, which may help to
control infections in the affected skin area.
• Potent Tonic Action: Shankha Bhasma, Saindhava Lavana, and Vidd
Lavaṇa provide mineral toning effects that can rejuvenate the skin by
balancing doshas (imbalances in bodily humors) and enhancing the tissue-
building process at the site of application.
• Circulatory Effects: Ingredients like Pippali and Chitrak can stimulate
local blood circulation, ensuring that nutrients and oxygen reach the
affected skin area for repair and healing.
• Metabolism:
• Topical Metabolism: The active compounds absorbed into the skin
are often metabolized locally in the dermis and epidermis by skin cells
(keratinocytes, fibroblasts). Many of the active compounds in the mask
may undergo local enzymatic transformations or may remain largely in
their active forms within the skin.
• Bhallataka and Chitrak's active principles (such as semecarpic acid,
cardanol) are known to have anti-inflammatory and anti-itch properties
and can help to regulate immune responses at the site of the skin
infection or inflammation. These compounds may be metabolized by skin
enzymes, leading to further bioactive metabolites that maintain their anti-
inflammatory and antimicrobial effects.
• Transdermal Absorption: If the compounds penetrate the skin
deeply, some may reach the subcutaneous tissue and may be processed
by the body's metabolic pathways, especially in cases of severe infection
or chronic skin damage. However, metabolism in the liver and systemic
circulation is less likely to play a major role in this formulation unless the
mask is applied in large quantities or for prolonged periods.
• . Excretion:
• Local Excretion: After the active compounds are metabolized
by the skin, they are likely excreted from the site via sweat glands
or sebum glands, especially for fat-soluble compounds like
Bhallataka and Chitrak.
• Systemic Excretion: In cases where some active ingredients
are absorbed into the bloodstream, they would be primarily
processed by the liver, and then excreted via the urinary system or
feces. However, for this topical formulation, significant systemic
absorption is unlikely unless used extensively over large areas of
the body. Most compounds will remain localized at the site of
application and will be excreted locally.
• Duration of Action:
• Short-term effects would include local reduction of
inflammation, pain relief, cooling of the affected skin, and
improvement in ulceration.
• Long-term effects could include skin regeneration and
infection control, as the ingredients like Bhallataka and Chitrak
promote tissue healing and immune regulation in the long run.
RESEARCH UPDATES

- A CLINICAL TRIAL ON THE EFFICACY OF BHALLATAKADI LEPA IN


CHARMAKEELA W.S.R. CUTANEOUS WARTS by Lokendra Pahadiya
and B. Swapna, PG Final Year Scholar, 2Assistant professor, PG
Department of Shalya Tantra, NIA, Jaipur, Rajasthan, India.
• भल्लातकादिक्वाथः – िैषज्य रत्िावली , उरुस्तमि रोर्ाचधकार
• िल्लातकामत ृ ाशुण्ठीिारुपर्थयापि
ु ियवाः ।
• पञ्िमलू ीद्वयोह्नम्रमा ऊरुस्तमिनिबहयर्ाः ।।
घटक द्रव्य
• शुद्ध िल्लातक - 1 part
• र्ुडूिी - 1 part
• िार्र - 1 part
• िे विारु - 1 part
• हरीतकी - 1 part
• पुिियवा - 1 part
• बबल्व - 1 part
• अरिी - 1 part
• शयोिाक - 1 part
• पाटला - 1 part
• र्ंिारी - 1 part
• शालपर्ी - 1 part
• पष्ृ िपर्ी - 1 part
• बह ृ ती - 1 part
• शुद्ध िल्लातक फल, चर्लोय, सोंठ, िे विारु, हरड़ के नछलके,
पुिियवा की जड़ एवं लघु तथा बह ृ त ् पञ्िमल
ू के द्रव्य (बबल्व,
अरर्ी, सोिापाठा, र्मिारी और पाढल इिकी छाल तथा
शालपर्ी, पह्ृ श्िपर्ी, छोटी कण्टकारी, बड़ी कण्टकारी और
र्ोखरू) इस सबको समप्रमार् में भमच्रमत कर कूट के ४ तोले
िर लेकर ३२ तोले जल में क्वचथत करके ८ तोले शेष रहिे
पर छािकर भम्रमी या शहि भमला के दिि में थोड़ा २ (िो-िो
तोले िर) मख ु के अनिर घी का लेप कर वपलािा िादहए। इस
क्वाथ के सेवि करिे से ऊरुस्तमि रोर् वविष्ट हो जाता है ॥
• मात्रा व अनप ु ान – 24 ml , मख ु में घत ृ का लेप कर
• उपयोग – उरुस्तमि
• पथ्य – िग्ु ध ,घतृ
• अपथ्य – उष्र् द्रव्य , आतप सेवि
PHARMACODYNAMICS
• Urustambha is a Vatavyadhi (neuromuscular disorder) described in Ayurveda,
characterized by stiffness, heaviness, and numbness in the thighs due to the
accumulation of Kapha and Meda (fat) obstructing Vata movement. It is
considered a Kapha-Meda Avarana (obstruction) disorder leading to impaired
circulation and function of Vata Dosha.
• 1. Kapha-Meda Vilayana (Breakdown of excess Kapha and Fat):
• Bhallataka, Haritaki, Punarnava, and Shunthi have strong Lekhana and
Medohara properties that help reduce the accumulation of Kapha and Meda,
which are the primary factors in Urustambha.
• 2. Srotoshodhana (Clearing Blocked Channels): Devdaru, Guduchi, Punarnava,
and Shunthi facilitate the removal of Avarana (obstruction) in the Srotas
(channels), restoring normal Vata flow and circulation.
• 3. Agnivardhana (Improvement of Digestion and Metabolism):
• Bhallataka, Shunthi, and Haritaki stimulate digestion and improve metabolism,
which prevents further Kapha-Meda accumulation.
• 4. Shothahara (Anti-inflammatory & Edema-reducing Action):-Punarnava,
Guduchi, and Devdaru reduce inflammation and swelling, relieving stiffness
and heaviness in the thighs.
• 5. Balya & Rasayana (Strengthening & Rejuvenation): Dvi Panchamula,
Guduchi, and Haritaki help in rejuvenating tissues and improving muscle
strength, counteracting the weakness caused by Urustambha.
PHARMACOKINETICS
• 1. Absorption (Aushadha Grahana & Pachana in Ayurveda)
• Shuddh Bhallataka, Shunthi, and Haritaki enhance Agni (digestive fire),
which facilitates better digestion and absorption of active
compounds.Guduchi and Devdaru contain small molecular weight
alkaloids and terpenoids, which are readily absorbed in the
gastrointestinal tract.
• Punarnava and Dvi Panchamula are rich in flavonoids and saponins that
undergo passive absorption in the intestines.
• The bioavailability is enhanced by Ushna (hot potency) and Deepana
(digestive stimulant) properties, which increase gastric motility and
absorption efficiency.
• 2. Distribution (Aushadha Vyapti in Ayurveda)- Lipid-soluble components
(e.g., Bhallataka’s bhilawanols, Devdaru’s sesquiterpenes) are distributed
via the lymphatic system and stored in adipose tissues, helping in
prolonged action against Meda Avarana (fat-based obstruction).Water-
soluble components (e.g., alkaloids in Guduchi and flavonoids in
Punarnava) rapidly enter systemic circulation and distribute to muscle
tissues, reducing inflammation and stiffness. Haritaki and Guduchi contain
tannins and glycosides that target the liver and muscle tissues, aiding
detoxification and rejuvenation.
• 3. Metabolism (Aushadha Paka in Ayurveda)- Primary metabolism
occurs in the liver (Yakrit Paka), where polyphenols, alkaloids, and
terpenoids are broken down into active metabolites. Punarnava’s
rotenoids and flavonoids undergo hepatic biotransformation into
anti-inflammatory and diuretic metabolites.
• Bhallataka and Shunthi stimulate hepatic enzymes, improving fat
metabolism and clearance of excess Meda (lipids).Guduchi and Dvi
Panchamula provide hepatoprotective effects, preventing oxidative
stress during metabolism.
• 4. Excretion (Aushadha Nissarana in Ayurveda)
• Major excretion pathways:
• Renal (urine): Punarnava and Guduchi promote diuresis, clearing
inflammatory mediators and metabolic waste.
• Fecal (stool): Haritaki’s mild laxative action ensures elimination of
undigested toxins (Ama).
• Sweat (Sweda): Ushna Virya herbs like Bhallataka and Shunthi
enhance perspiration, promoting toxin removal through the skin.

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