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Rheumatology Erythrocyte Sedimentation Rate: General Information

The Erythrocyte Sedimentation Rate (ESR) is a non-specific indicator of disease presence, measuring how quickly red blood cells settle in anticoagulated blood over one hour, with normal values being less than 20 mm/H. ESR increases with age and can be significantly elevated in conditions such as Giant Cell Arteritis and Multiple Myeloma. Factors that can lower ESR include Polycythemia and Sickle Cell Anemia.

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25 views1 page

Rheumatology Erythrocyte Sedimentation Rate: General Information

The Erythrocyte Sedimentation Rate (ESR) is a non-specific indicator of disease presence, measuring how quickly red blood cells settle in anticoagulated blood over one hour, with normal values being less than 20 mm/H. ESR increases with age and can be significantly elevated in conditions such as Giant Cell Arteritis and Multiple Myeloma. Factors that can lower ESR include Polycythemia and Sickle Cell Anemia.

Uploaded by

ilkelambrechts101
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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ERYTHROCYTE SEDIMENTATION RATE

RHEUMATOLOGY
ERYTHROCYTE SEDIMENTATION RATE ESR
GENERAL INFORMATION

 Erythrocyte Sedimentation Rate is a Sensitive but Non-Specific Indicator of the


Presence of Disease
 Measures the Rate at which Red Blood Cells fall through a Column of Anticoagulated
Blood over 1 Hour
 Inflammation increases the Rate at which this occurs

NORMAL RANGE

 < 20 mm/H

ESR RANGE

 ESR rises with Age


 Westergren Method used to Determine the Upper Limit of Normal
o Male - Age / 2
o Female - (Age + 10) / 2

CAUSES OF SEVERELY RAISED ESR ABOVE 100 [GRIM-COT]

 Giant Cell Arteritis


 Renal Cell Carcinoma
 Infective Endocarditis
 Multiple Myeloma

 Connective Tissue Disease


 Osteomyelitis
 TB

CONDITIONS WHICH LOWER THE ESR

 Polycytemia
 Sickle Cell Anemia

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