1.

Find out ‘incorrect’ statement

(1) Inulin a polysaccharide is obtained from the roots of Dahlia

(2) GLUT-4 protein enables glucose transport into cells

(3) Ribose sugar is present in RNA and ATP

(4) Sucrose is a dipeptide commonly known as Aspartame

2. Which of the following statements is ‘not correct’ w.r.t. starch?

(1) Starch is a stored food of plants

(2) Starch is a polymer of α-glucose units

(3) Amylose and amylopectin are two types of components of starch

(4) Amylose is linear structure consisting of glucose units joined by α (1, 4) glycosidic and α (1, 6)

glycosidic linkages

3. Amino acid alanine is

(1) Mono amino dicarboxylic amino acid

(2) Mono amino monocarboxylic amino acid

(3) Mono carboxylic diamino amino acid

(4) Acidic amino acid

4. Which one is the most abundant protein in the animal world?

(1) Insulin

(2) Collagen

(3) Haemoglobin

(4) Myosin

5. Mark the wrong statement

(1) Zinc is a cofactor for proteolytic enzyme carboxypeptidase

(2) Km (Michaelis Menten Constant) is numerically equivalent to ½ Vmax

(3) Each strand of DNA appears like a helical staircase. Each step of ascent, strand turns 36°

(4) Tyrosine, Phenylalanine and Tryptophan are aromatic amino acids

6. Which of the following is not an essential fatty acid?

(1) Stearic acid

(2) Arachidonic acid

(4) Linoleic acid

7. Mark the incorrect statement

(1) Lipids are not strictly macromolecules

(2) Starch-l2 complex gives blue colour, as it can hold iodine molecules in the helical portion

(3) Living state is a non-equilibrium steady state to be able to perform work

(4) The blood concentration of glucose in normal healthy individual is 4.2 to 6.1 mmol/mL

8. Following are the examples of primary metabolites, except

(1) Lecithin

(3) Triglyceride

(2) Cholesterol

(4) Cellulose

9. Inhibition of succinic dehydrogenase by malonate which closely resembles the substrate succinate in

structure is an example of competitive inhibition in which

(1) Decrease in Vmax and Km unaffected

(2) No change in Vmax and increase in Km

(3) Decrease in both Vmax and Km

(4) Decrease in Vmax and increase in Km

10. α-Keratin protein assumes secondary structure through the formation of

(1) Intrachain hydrogen bond

(2) Interchain hydrogen bond

(3) Peptide bond

(4) Interchain disulphide bond

11. Cholesterol is

(1) Wax

(2) Triglyceride

(3) Steroid

(4) Phospholipid

12. Select the wrong statement

(2) Ribozymes are nucleic acids with catalytic power

(3) Mannitol is a sugar alcohol

(4) Cerebroside is a steroid

13. Which of the following glycosidic bond is found in sucrose?

(1) α 1, 4 (2) β 1, 4

(3) α 1, 6 (4) α - 1, β - 2

14. Mark the odd one

(1) Adenylic acid

(2) Guanylic acid

(3) Cytidine monophosphate

(4) Ascorbic acid

15. Protein part of conjugated enzyme is known as

(1) Holoenzyme

(2) Coenzyme

(3) Apoenzyme

(4) Prosthetic group

16. The inhibitors which block the active sites of enzyme are

(1) Allosteric modulators

(2) Competitive inhibitors

(3) Non-competitive inhibitors

(4) Feedback inhibitors

17. Increased efficiency of enzymes depends upon

(1) Number of active sites

(2) Decrease in temperature

(3) Increase in pH

(4) More than one option is correct

18. Which statement regarding coenzyme is ‘incorrect’?

(1) Most of the coenzymes are nucleotides and are composed of vitamins
(2) Coenzymes are the active constituents of enzymes

(3) Every coenzyme is a cofactor and every cofactor is a coenzyme

(4) Every coenzyme is a cofactor but every cofactor is not a coenzyme

19. Allosteric modulation is due to the inhibitory action faced by enzyme by

(1) Competitive reversible inhibition

(2) Non-competitive irreversible inhibition

(3) Accumulation of products

(4) Accumulation of substrate

20. Select the type of enzyme involved in the following reaction

S – G + S′ → S + S′ – G

(1) Lyase

(2) Isomerase

(3) Transferase

(4) Hydrolase

21. Which of the following bond is not present in a single nucleotide?

(1) Hydrogen bond

(2) Glycosidic bond

(3) Phosphodiester

(4) Both (1) & (3)

22. On hydrolysis, uridine would not yield

(1) Phosphate group

(2) Monosaccharide sugar

(3) Heterocyclic compound

(4) Both (1) & (3)

23. Find the incorrectly matched amino acid with its function.
24. A competitive inhibitor like malonate

(1) Does affect the Vmax i.e. maximum velocity of the reaction

(2) Gets chemically changed by enzyme action

(3) Increases the apparent Km for a given substrate

(4) Can bind with active site as well as other sites on enzymes

25. How many of the given ones belong to single category w.r.t. type of functional aldehydic group?

Maltose, Lactose, Ribose, Fructose, Inulin

(3) Two (4) Five

26. Which of the following ones is not the function of steroids?

(1) Essential component of animal plasmalemma

(2) To form bile salts

(3) To form channels and pumps

(4) To form vitamin D

27. A diglyceride differs from a monoglyceride in

(1) Having two molecules of trihydroxypropane

(2) Lacking one unsaturated fatty acid

(3) Having one additional molecule of glycerol

(4) Possessing one additional fatty acid

28. Identify the structure given below and find out the incorrect statements/options for it.
(a) A component of phosphoglycerides, thereby possessing phosphate group.

(b) A purine nucleotide that can become a component of DNA as well as RNA.

(c) Can become an energy carrier on further phosphorylation.

(d) A pyrimidine nucleotide, found in RNA only.

(1) (a) & (d) (2) (a), (b) & (d)

(3) (c) & (d) (4) (c) only

29. A pair of heterocyclic amino acids is

(1) Phenylalanine and tryptophan (2) Histidine and arginine

(3) Proline and histidine (4) Hydroxyproline and tyrosine

30. The ‘living state’

(1) Can never anyhow be related to metabolism

(2) Is a non-equilibrium state with molecules in a metabolic flux

(3) Is an equilibrium steady-state without any metabolic flux

(4) Is a constant effort to prevent attaining equilibrium without any energy input

31. At a particular pH and temperature conditions, an inhibitor irreversibly reducing Vmax of a reaction
does not

(1) Affect the binding of an enzyme for its substrate

(2) Change the Michaelis-Menten constant for that reaction

(3) Compete with the substrate for active site

(4) All of these

32. The most important form of energy currency in living system is the bond energy in a chemical called

(1) NADP

(3) FMN

(2) FAD

(4) ATP

33. Find out the correct statement.

(1) Insulin is a heteropolymer

(2) Triglycerides are truely or strictly macromolecules

(3) High temperature leads to denaturation as well as renaturation in proteins

34. How many of the following are common features of cellobiose and maltose?

(a) -1, 4-glycosidic linkage.

(b) Two glucose residues

(c) Non-reducing sugars.

(d) Rich amounts present in cotton and jute.

(e) No feature is common in them, as one is polysaccharide and another is disaccharide.

(1) (a), (b) & (c) (2) (a), (c) & (d)

(3) (b) only (4) (a) & (b) only

35. The incorrectly matched column is

36. Find out the incorrect statement.

(1) Glucose, galactose, maltose are reducing monosaccharides while sucrose is non-reducing in nature.

(2) Adenine cannot pair up with cytosine.

(3) Steroids are derived lipids

(4) Inhibition of hexokinase by glucose-6-phosphate is an example of allosteric modulation.

37. Find out the correct match

(1) Holoenzyme = Apoenzyme + Co-factor

(2) Apoenzyme = Co-factor + Co-enzyme

(3) Conjugated enzyme = Simple enzyme + apoenzyme

(4) Prosthetic group = Co-factor – Co-enzyme

38. Amino acids are substituted methanes having following groups except

1) -COOH group
2) Variable R group

3) -CHO group

4) -NH2 group

39. The following glycans are polymers of glucose except

1) Cellulose

2) Amylopectin

3) Agarose

4) Glycogen

40. Which of the following is a nucleoside?

1) FMN

2) AMP

3) Uridine

4) Thymidylic acid

41. Match the following columns and select the correct option.

Column I Column II
(a) Helical pitch i) 36⁰

(b) Axial rise ii) Hydrogen bonds

(c) Twist angle iii) 3.4 nm

(d) Bonds joining two strands iv) 0.34 nm

1) a (iv), b (i), c (ii), d (iii)

2) a (iii), b (iv), c (i), d (ii)

3) a (ii), b (i), c (iii), d (iv)

4) a (iv), b (iii), c (ii), d (i)

42. In which of the following molecules, will you find ester bonds?

A. DNA B. RNA C. Lecithin D. Trihydroxypropane E. Amylose

1) A 2) A, B 3) A, B, C 4) C, D

43. The storage polysaccharide in human liver is

44. Which of the following has peptide bonds?

1) Cellulose 2) Natural silk 3) Cotton fibre 4) Arthropod exoskeleton

45. If three amino acids are linked by peptide bonds, the resultant molecule is termed

1) tricarboxylic acid

2) triamine

3) tripeptide

4) amide

46. An enzyme has an EC No. 3.2.1.48. Its most likely

1) Alcohol dehydrogenase

2) Hexokinase

3) DNA ligase

4) Sucrase

47. Which of the following is incorrect w.r.t. glucose?

1) Grape sugar

2) Dextrose

3) Respiratory substrate

4) Fruit sugar

48. Acetate is converted to _____________ in liver.

1) Triglyceride

2) Prothrombin

3) Cholesterol

4) Glycogen

49. Which of the following secondary metabolite is used as a drug to treat cancer?

1) Curcumin

2) Vinblastine

3) Concanavalin

4) Morphine

50. Choose the protein which exists as quaternary structure.

2) Myoglobin

3) Lysozyme

4) None of these

51. Choose the biomolecules which would not be present in acid insoluble retentate.

Glucose, Collagen, Lecithin, AMP, Amylose, Methionine, Glucan, RNA, Enkephalin, Maltose, Cystine

(1) 4

(2) 5

(3) 6

(4) 7

52. In which of the following molecules, will you find ester bonds?

A. DNA B. RNA C. Lecithin D. Trihydroxypropane E. Amylose