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Assignment Principles of Drug Discovery (MPL203-T)

The document outlines two assignments for the M. Pharmacy (Pharmacology) II Semester course on Principles of Drug Discovery, each with a maximum of 30 marks. Students are required to answer three long answer questions from a list that includes topics such as protein structure classification, transgenic animals, rational drug design methods, and molecular docking. Each question is associated with specific course outcomes and program outcomes.

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kuldeepmalik98022
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58 views2 pages

Assignment Principles of Drug Discovery (MPL203-T)

The document outlines two assignments for the M. Pharmacy (Pharmacology) II Semester course on Principles of Drug Discovery, each with a maximum of 30 marks. Students are required to answer three long answer questions from a list that includes topics such as protein structure classification, transgenic animals, rational drug design methods, and molecular docking. Each question is associated with specific course outcomes and program outcomes.

Uploaded by

kuldeepmalik98022
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd

M.M.

COLLEGE OF PHARMACY
MAHARISHI MARKANDESHWAR (DEEMED TO BE UNIVERSITY)
MULLANA- AMBALA, HARYANA (INDIA) -133 207
(Established Under Section 3 of UGC, Act., 1956)
(Accredited by NAAC with Grade ‘A++’)

M. Pharmacy (Pharmacology) IInd Semester


Principles of Drug Discovery (MPL203-T)
Assignment-I
Maximum Marks: 30
Answer any 3.

Long answer questions: Marks CO PO PEO


10 CO-3 PO-1,2,3,4,6,11 PEO-
1. Give the detailed classification of protein structure and add the 1,2,3,4
definitions of Motifs, Domains, and folds.

10 CO-1,3,5 PO-1,2,3,4,6,11 PEO-


2. Write a short note on followings: 1,2,3,4
a) Transgenic Animals
b) SiRNAs

10 CO-1,3 PO-1,2,3,4,6,11 PEO-


3. Write a short note on followings: 1,2,3,4
a) Zinc finger Proteins
b) Anti-sense oligonucleotides
10 CO-4, 5 1,2,3,4,6,11 PEO-
4. Elaborate in detail about the techniques for Protein Structure 1,2,3,4
Prediction.
M.M. COLLEGE OF PHARMACY
MAHARISHI MARKANDESHWAR (DEEMED TO BE UNIVERSITY)
MULLANA- AMBALA, HARYANA (INDIA) -133 207
(Established Under Section 3 of UGC, Act., 1956)
(Accredited by NAAC with Grade ‘A++’)

M. Pharmacy (Pharmacology) IInd Semester


Principles of Drug Discovery (MPL203-T)
Assignment-II
Maximum Marks: 30
Answer any 3.

Long answer questions: Marks CO PO PEO


10 CO- PO-1,2,3,4,6,11 PEO-
1. Give the detailed note on Rational Drug Design Methods Structure 1,3,4,5 1,2,3,4
and Pharmacophore based approaches.

10 CO- PO-1,2,3,4,6,11 PEO-


2. Write a short note on followings: 1,3,4,5 1,2,3,4
a) Hansch analysis
b) SAR versus QSAR

10 CO- PO-1,2,3,4,6,11 PEO-


3. Write a short note on followings: 1,3,4,5 1,2,3,4
a) De novo drug design
b) Prodrug design in improving patient acceptability and
Drug solubility.
10 CO- 1,2,3,4,6,11 PEO-
4. Elaborate in detail about the Molecular docking and its 1,3,4,5 1,2,3,4
classification.

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