Statistics 1S1 :Pre-prepared Tutorial Questions : 2025 page 6
Week 11 Tutorial 10: Nonparametric Methods
1. A study is carried out to assess the effectiveness of two analgesic drugs (drug A and drug B) in
providing relief (hours of relief) in 12 patients suffering from arthritis. Drug B has performed better
in 9 patients (di > 0) and drug A has performed better in 3 patients (di < 0) . Is there any evidence
that one drug provides longer relief than the other.
2. In the past the number of defective pills (where defective is defined as pills that do not match some
quality control criteria) produced by a machine per lot of 1 000 has a median of 8. To test whether the
machine is still producing the same amount of defectives, the machine’s output is tested by randomly
selecting 30 “lots” of 1 000 pills. The number of defectives in each lot, in order of production, are 3,
11, 6, 22, 9, 12, 11, 12, 7, 12, 8, 14, 10, 7, 6, 8, 16, 10, 9, 10, 13, 8, 4, 10, 12, 9, 13, 11, 9 and 10.
Test that the median has increased relative to the prior median value of 8 per 1 000.
Conduct this test using (an appropriate) sign test.
3. In the past the number of defective pills (where defective is defined as pills that do not match some
quality control criteria) produced by a machine per lot of 1 000 has a median of 8. To test whether the
machine is still producing the same amount of defectives, the machine’s output is tested by randomly
selecting 30 “lots” of 1 000 pills. The number of defectives in each lot, in order of production, are 3,
11, 6, 22, 9, 12, 11, 12, 7, 12, 8, 14, 10, 7, 6, 8, 16, 10, 9, 10, 13, 8, 4, 10, 12, 9, 13, 11, 9 and 10.
(a) Capture these data in Statistica.
(b) Plot a boxplot and a normal probability plot (QQ plot). What can you infer?
For the record:
(c) Test the normality assumption.
(d) Test that the median has increased relative to the prior median value of 8 per 1 000. Conduct
this test using an appropriate Wilcoxon test.
4. The clients at a mental health clinic are periodically classified as “condition improved”, “condition
worsened” or “no change in condition”. A check of 15 patients reveals that 10 are classified as
“condition improved”, 3 as “condition worsened” and two as “no change in condition”. Do these data
provide evidence that the median condition is improving, i.e. that the median condition is greater than
0?
5. Consider the Health Services Administration case study on page 365 (347). Answer
(a) 9.7 (9.16);
(b) 9.8 (9.17).
6. Consider Otolaryngology, Pediatrics case study on page 366 (348). Answer questions:
(a) 9.13 (9.34);
6
Statistics 1S1 :Pre-prepared Tutorial Questions : 2025 page 7
(b) 9.14 (9.35);
(c) 9.15 (9.36);
(d) 9.16 (9.37).
Additional Questions
7. The table below shows the hours of relief provided by two analgesic drugs in 16 patients suffering
from arthritis. Is there any evidence that one drug provides longer relief than the other? Take it that
there are no reasonable grounds to assume normality.
Case 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
Drug A 2.0 3.6 2.6 2.6 7.3 3.4 14.9 6.6 2.3 2.0 6.8 8.5 7.9 11.2 4.5 9.1
Drug B 3.5 5.7 2.9 2.4 9.9 3.3 16.7 6.0 3.8 4.0 9.1 20.9 5.6 11.9 5.8 8.0
