SILVER OAK UNIVERSITY
Silver college of Pharmacy (067)
Programme Name: [Link] (18)
Subject Name: Pharmaceutics-I
Subject Code: 1180673103
Semester: I
Prerequisite:
This course is designed to impart a fundamental knowledge on the preparatory pharmacy with arts and
science of preparing the different conventional dosage forms.
Objective: Upon completion of this course the student should be able to:
1. Know the history of profession of pharmacy
2. Understand the basics of different dosage forms, pharmaceutical incompatibilities and pharmaceutical
calculations
3. Understand the professional way of handling the prescription
4. Preparation of various conventional dosage forms
Teaching Scheme:
Teaching Scheme
L T P Contact Hours Credit
3 1 4 8 6
Content:
Unit Teaching Weightage
Contents
No. Hours %
Historical background and development of profession of
pharmacy: History of profession of Pharmacy in India in relation
to pharmacy education, industry and organization, Pharmacy as a
career, Pharmacopoeias: Introduction to IP, BP, USP and Extra
Pharmacopoeia.
Dosage forms: Introduction to dosage forms, classification and
1 10 Hrs 22%
definition
Prescription: Definition, Parts of prescription, handling of
Prescription and Errors in prescription.
Posology: Definition, Factors affecting posology. Pediatric dose
calculations based on age, body weight and body surface area.
Pharmaceutical calculations: Weights and measures – Imperial
& Metric system, Calculations involving percentage solutions,
alligation, proof spirit and isotonic solutions based on freezing
point and molecular weight.
Powders: Definition, classification, advantages and
2 disadvantages, Simple & compound powders – official 10 Hrs 22%
preparations, dusting powders, effervescent, efflorescent and
hygroscopic powders, eutectic mixtures. Geometric dilutions.
Liquid dosage forms: Advantages and disadvantages of liquid
dosage forms. Excipients used in formulation of liquid dosage
forms. Solubility enhancement techniques
Monophasic liquids: Definitions and preparations of Gargles,
Mouthwashes, Throat Paint, Eardrops, Nasal drops, Enemas,
Syrups, Elixirs, Liniments and Lotions.
Biphasic liquids:
Suspensions: Definition, advantages and disadvantages,
3 classifications, Preparation of suspensions; Flocculated and 10 Hrs 22%
Deflocculated suspension & stability problems and methods to
overcome.
Emulsions: Definition, classification, emulsifying agent, test for
the identification of type of Emulsion, Methods of preparation &
stability problems and methods to overcome.
Suppositories: Definition, types, advantages and disadvantages,
types of bases, methods of preparations. Displacement value &
its calculations, evaluation of suppositories.
4 08 Hrs 18%
Pharmaceutical incompatibilities: Definition, classification,
physical, chemical and therapeutic incompatibilities with
examples.
Semisolid dosage forms: Definitions, classification,
mechanisms and factors influencing dermal penetration of drugs.
5 Preparation of ointments, pastes, creams and gels. Excipients 07Hrs 16%
used in semi solid dosage forms. Evaluation of semi solid
dosages forms
Total 45 Hrs
Course Outcome: After Completion of Syllabus students will able to
Sr. No. CO statement Unit No
Know the history of profession of pharmacy and official compendia Understand
the basics of different dosage forms, Understand the professional way of handling
CO-1 1
the prescription and dispensing of medications, Fundamental knowledge of
calculation of Dose by different formula
Describe formulation and evaluation aspect of monophasic liquid formulations,
CO-2 2
dispensing aspects of dosage forms like powders
CO-3 Understand the dispensing aspects of dosage forms like emulsion and Suspension 3
To learn the basics of different pharmaceutical incompatibilities and Describe use
CO-4 of ingredients in formulation, preparation method and evaluation method of 4
suppositories
Upon completion of this unit the student will have fundamental knowledge
CO-5 in preparing conventional Semisolid dosage forms and Selection of suitable 5
packaging material (container-closure) for the preparation.
Teaching & Learning Methodology: -
The various methods or tools follows by the faculties to teach the above subject are:
1. Student centered learning
2. Experimental learning
Experiments:
Students will perform following Experiments OR
1. Syrups
a) Syrup IP’66
b) Compound syrup of Ferrous Phosphate BPC’6
2. Elixirs
a) Piperazine citrate elixir
b) Paracetamol pediatric
3. Linctuses
a) Terpin Hydrate Linctus IP’66
b) Iodine Throat Paint (Mandles Paint)
4. Solutions
a) Strong solution of ammonium acetate
b) Cresol with soap solution
c) Lugol’s solution
5. Suspensions
a) Calamine lotion
b) Magnesium Hydroxide mixture
c) Aluminimum Hydroxide gel
6. Emulsions
a) Turpentine Liniment
b) Liquid paraffin emulsion
7. Powders and Granules
a) ORS powder (WHO)
b) Effervescent granules
c) Dusting powder
d) Divided powder
8. Suppositories
a) Glycero gelatin suppository
b) Coca butter suppository
c) Zinc Oxide suppository
9. Semisolids
a) Sulphur ointment
b) Non staining-iodine ointment with methyl salicylate
c) Carbopal gel
10. Gargles and Mouthwashes
a) Iodine gargle
b) Chlorhexidine mouthwash
Books Recommended:
1. H.C. Ansel et al., Pharmaceutical Dosage Form and Drug Delivery System, Lippincott Williams and Walkins,
New Delhi.
2. Carter S.J., Cooper and Gunn’s-Dispensing for Pharmaceutical Students, CBS publishers, New Delhi.
3. M.E. Aulton, Pharmaceutics, The Science& Dosage Form Design, Churchill Livingstone, Edinburgh.
4. Indian pharmacopoeia.
5. British pharmacopoeia.
6. Lachmann. Theory and Practice of Industrial Pharmacy, Lea& Febiger Publisher, The University of Michigan.
7. Alfonso R. Gennaro Remington. The Science and Practice of Pharmacy, Lippincott Williams, New Delhi.
8. Carter S.J., Cooper and Gunn’s. Tutorial Pharmacy, CBS Publications, New Delhi.
9. E.A. Rawlins, Bentley’s Text Book of Pharmaceutics, English Language Book Society, Elsevier Health
Sciences, USA.
10. Dilip M. Parikh: Handbook of Pharmaceutical Granulation Technology, Marcel Dekker, INC, New York.
11. Francoise Nieloud and Gilberte Marti-Mestres: Pharmaceutical Emulsions and Suspensions, Marcel Dekker,
INC, New York.
Co.
PO1 PO2 PO3 PO4 PO5 PO6 PO7 PO8 PO9 PO10 PO11 PSO1 PSO2
No.
CO-1 3 1 2 3 1 3 1 2 3 3 3 3 2
CO-2 3 1 1 3 1 1 2 2 2 3 3 2 2
CO-3 3 1 1 2 - 3 2 1 2 2 2 3 2
CO-4 3 - 2 2 - 2 - 2 1 2 2 2 3
CO-5 3 - 2 3 - 2 - - 2 2 2 3 2
