Aniline MATERIAL SAFETY DATA SHEET
CAS No 62-53-3 SDS/MSDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifiers
Product name : Aniline
CAS-No. : 62-53-3
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Industrial & for professional use only.
1.3 Details of the supplier of the safety data sheet
Company : Central Drug House (P) Ltd
7/28 Vardaan House
Ansari Road Daryaganj
New Delhi-110002
INDIA
Telephone : +91 11 49404040
Email :
[email protected]1.4 Emergency telephone number
Emergency Phone # : +91 11 49404040 (9:00am - 6:00 pm) [Office hours]
SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008
Acute toxicity, Oral (Category 3), H301
Acute toxicity, Inhalation (Category 3), H331
Acute toxicity, Dermal (Category 3), H311
Serious eye damage (Category 1), H318
Skin sensitisation (Category 1), H317
Germ cell mutagenicity (Category 2), H341
Carcinogenicity (Category 2), H351
Specific target organ toxicity - repeated exposure (Category 1), H372
Specific target organ toxicity - repeated exposure (Category 1), Blood, H372
Acute aquatic toxicity (Category 1), H400
Chronic aquatic toxicity (Category 1), H410
For the full text of the H-Statements mentioned in this Section, see Section 16.
Classification according to EU Directives 67/548/EEC or 1999/45/EC
T Toxic R23/24/25, R48/23/24/25
R40
R68
Xi Irritant R41
R43
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N Dangerous for the R50
environment
For the full text of the R-phrases mentioned in this Section, see Section 16.
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008
Pictogram
Signal word Danger
Hazard statement(s)
H301 + H311 + H331 Toxic if swallowed, in contact with skin or if inhaled
H317 May cause an allergic skin reaction.
H318 Causes serious eye damage.
H341 Suspected of causing genetic defects.
H351 Suspected of causing cancer.
H372 Causes damage to organs (Blood) through prolonged or repeated
exposure.
H410 Very toxic to aquatic life with long lasting effects.
Precautionary statement(s)
P261 Avoid breathing vapours.
P273 Avoid release to the environment.
P280 Wear protective gloves/ eye protection/ face protection.
P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/
physician.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing.
P311 Call a POISON CENTER or doctor/ physician.
Supplemental Hazard none
Statements
2.3 Other hazards
This substance/mixture contains no components considered to be either persistent, bioaccumulative and
toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
SECTION 3: Composition/information on ingredients
3.1 Substances
Molecular weight : 93,13 g/mol
CAS-No. : 62-53-3
EC-No. : 200-539-3
Index-No. : 612-008-00-7
Hazardous ingredients according to Regulation (EC) No 1272/2008
Component Classification Concentration
Aniline
CAS-No. 62-53-3 Acute Tox. 3; Eye Dam. 1; <= 100 %
EC-No. 200-539-3 Skin Sens. 1; Muta. 2; Carc. 2;
Index-No. 612-008-00-7 STOT RE 1; Aquatic Acute 1;
Aquatic Chronic 1; H301 +
H311 + H331, H317, H318,
H341, H351, H372, H410
Hazardous ingredients according to Directive 1999/45/EC
Component Classification Concentration
Aniline
CAS-No. 62-53-3 T, N, Carc.Cat.3, Mut.Cat.3, <= 100 %
EC-No. 200-539-3 R23/24/25 - R40 - R41 - R43 -
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Index-No. 612-008-00-7 R48/23/24/25 - R68 - R50
For the full text of the H-Statements and R-Phrases mentioned in this Section, see Section 16
SECTION 4: First aid measures
4.1 Description of first aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician.
In case of eye contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed
Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with
water. Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in
section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available
SECTION 5: Firefighting measures
5.1 Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx)
5.3 Advice for firefighters
Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information
Use water spray to cool unopened containers.
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures
Wear respiratory protection. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Remove all
sources of ignition. Evacuate personnel to safe areas. Beware of vapours accumulating to form
explosive concentrations. Vapours can accumulate in low areas.
For personal protection see section 8.
6.2 Environmental precautions
Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the
environment must be avoided.
6.3 Methods and materials for containment and cleaning up
Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and
place in container for disposal according to local regulations (see section 13). Keep in suitable, closed
containers for disposal.
6.4 Reference to other sections
For disposal see section 13.
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SECTION 7: Handling and storage
7.1 Precautions for safe handling
Avoid contact with skin and eyes. Avoid inhalation of vapour or mist.
Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic
charge.
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are
opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): Non-combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
7.3 Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
SECTION 8: Exposure controls/personal protection
8.1 Control parameters
Components with workplace control parameters
8.2 Exposure controls
Appropriate engineering controls
Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling
the product.
Personal protective equipment
Eye/face protection
Tightly fitting safety goggles. Faceshield (8-inch minimum). Use equipment for eye protection
tested and approved under appropriate government standards such as NIOSH (US) or EN
166 (EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique
(without touching glove's outer surface) to avoid skin contact with this product. Dispose of
contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.
The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and
the standard EN 374 derived from it.
Body Protection
Complete suit protecting against chemicals, The type of protective equipment must be selected
according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection
Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator with
multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to
engineering controls. If the respirator is the sole means of protection, use a full-face supplied air
respirator. Use respirators and components tested and approved under appropriate government
standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into
the environment must be avoided.
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
a) Appearance Form: liquid
b) Odour No data available
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c) Odour Threshold No data available
d) pH 8,8 at 36 g/l at 20 °C
e) Melting point/freezing Melting point/range: -5,99 °C
point
f) Initial boiling point and
boiling range 182 °C -185°C
70 - 71 °C at 13 hPa
g) Flash point 70 °C - closed cup
h) Evaporation rate No data available
i) Flammability (solid, gas) No data available
j) Upper/lower Upper explosion limit: 23 %(V)
flammability or Lower explosion limit: 1,3 %(V)
explosive limits
k) Vapour pressure 0,49 hPa at 20 °C
0,8 hPa at 20 °C
l) Vapour density 3,22 - (Air = 1.0)
m) Relative density 1,020 – 1.025 g/cm3
No data available
n) Water solubility
log Pow: 0,91
o) Partition coefficient: n-
octanol/water
No data available
p) Auto-ignition
temperature
190 °C -
q) Decomposition
temperature
No data available
r) Viscosity
No data available
s) Explosive properties
No data available
t) Oxidizing properties
9.2 Other safety information
42,12 mN/m at 25 °C
Surface tension
3,22 - (Air = 1.0)
Relative vapour density
SECTION 10: Stability and reactivity
10.1 Reactivity
No data available
10.2 Chemical stability
Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions
No data available
10.4 Conditions to avoid
Heat, flames and sparks.
10.5 Incompatible materials
Oxidizing agents, Iron and iron salts., Zinc
10.6 Hazardous decomposition products
Other decomposition products - No data available
In the event of fire: see section 5
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SECTION 11: Toxicological information
11.1 Information on toxicological effects
Acute toxicity
LD50 Oral - Rat - 250 mg/kg
LC50 Inhalation - Mouse - 4 h - 248 ppm
LD50 Dermal - Rabbit - 836 mg/kg
Skin corrosion/irritation
Skin - Rabbit
Result: No skin irritation
Serious eye damage/eye irritation
Eyes - Rabbit
Result: Severe eye irritation
Respiratory or skin sensitisation
May cause sensitisation by skin contact.
Germ cell mutagenicity
Laboratory experiments have shown mutagenic effects. In
vitro tests showed mutagenic effects
Carcinogenicity
This product is or contains a component that has been reported to be possibly carcinogenic based on its
IARC, ACGIH, NTP, or EPA classification.
Limited evidence of carcinogenicity in animal studies
IARC: 3 - Group 3: Not classifiable as to its carcinogenicity to humans (Aniline)
Reproductive toxicity
No data available
Specific target organ toxicity - single exposure
No data available
Specific target organ toxicity - repeated exposure
Causes damage to organs through prolonged or repeated exposure. - Blood
Aspiration hazard
No data available
Additional Information
RTECS: Not available
Absorption into the body leads to the formation of methemoglobin which in sufficient concentration causes
cyanosis. Onset may be delayed 2 to 4 hours or longer., Cyanosis, Headache, Vomiting, Nausea,
Incoordination., fatigue, Dizziness, Drowsiness, Confusion., Weakness, Unconsciousness, Symptoms may
be delayed.
To the best of our knowledge, the chemical, physical, and toxicological properties have not been
thoroughly investigated.
SECTION 12: Ecological information
12.1 Toxicity
Toxicity to fish LC50 - Oncorhynchus mykiss (rainbow trout) - 10,6 mg/l - 96,0 h
Toxicity to daphnia and EC50 - Daphnia magna (Water flea) - 80 - 380 mg/l - 48 h
other aquatic
invertebrates
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semi-static test EC50 - Daphnia magna (Water flea) - 0,16 mg/l - 48 h
Toxicity to algae EC50 - SELENASTRUM - 19 mg/l - 72 h
12.2 Persistence and degradability
Biodegradability aerobic - Exposure time 30 d
Result: 90 % - Readily biodegradable.
(OECD Test Guideline 301D)
12.3 Bioaccumulative potential
No data available
12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent, bioaccumulative and
toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
12.6 Other adverse effects
Very toxic to aquatic life with long lasting effects.
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Product
This combustible material may be burned in a chemical incinerator equipped with an afterburner and
scrubber. Offer surplus and non-recyclable solutions to a licensed disposal company.
Contaminated packaging
Dispose of as unused product.
SECTION 14: Transport information
14.1 UN number
ADR/RID: 1547 IMDG: 1547 IATA: 1547
14.2 UN proper shipping name
ADR/RID: ANILINE
IMDG: ANILINE
IATA: Aniline
14.3 Transport hazard class(es)
ADR/RID: 6.1 IMDG: 6.1 IATA: 6.1
14.4 Packaging group
ADR/RID: II IMDG: II IATA: II
14.5 Environmental hazards
ADR/RID: yes IMDG Marine pollutant: yes IATA: no
14.6 Special precautions for user
No data available
SECTION 15: Regulatory information
This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
No data available
15.2 Chemical Safety Assessment
For this product a chemical safety assessment was not carried out
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SECTION 16: Other information
Full text of H-Statements referred to under sections 2 and 3.
Acute Tox. Acute toxicity
Aquatic Acute Acute aquatic toxicity
Aquatic Chronic Chronic aquatic toxicity
Carc. Carcinogenicity
Eye Dam. Serious eye damage
H301 Toxic if swallowed.
H301 + H311 + Toxic if swallowed, in contact with skin or if inhaled
H331
H311 Toxic in contact with skin.
H317 May cause an allergic skin reaction.
H318 Causes serious eye damage.
H331 Toxic if inhaled.
H341 Suspected of causing genetic defects.
H351 Suspected of causing cancer.
Full text of R-phrases referred to under sections 2 and 3
N Dangerous for the environment
T Toxic
R23/24/25 Toxic by inhalation, in contact with skin and if swallowed.
R40 Limited evidence of a carcinogenic effect.
R41 Risk of serious damage to eyes.
R43 May cause sensitisation by skin contact.
R48/23/24/25 Toxic: danger of serious damage to health by prolonged exposure through inhalation,
in contact with skin and if swallowed.
R50 Very toxic to aquatic organisms.
R68 Possible risk of irreversible effects.
Further information
The above information is believed to be correct but does not purport to be all inclusive and shall be
used only as a guide. The information in this document is based on the present state of our knowledge
and is applicable to the product with regard to appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Central Drug House (P) Ltd and its Affiliates shall not be
held liable for any damage resulting from handling or from contact with the above product. See
www.cdhfinechemical.com for additional terms and conditions of sale.
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