Last Resort Revision (LRR)

PYT + PYQ

Dr. Ankit Kumar

MBBS, MD, DM
Clinical Pharmacology

1
 Day 1 LRR Day 2

1. General pharmacology 1. Blood

2. ANS 2. CNS
3. Glaucoma 3. Autacoids
4. Respiratory 4. Endocrine
5. Kidney 5. Antimicrobials
6. CVS 6. Anticancer,
Immunomodulators
General pharmacology

3
Q1. Forced alkaline diuresis is done for the poisoning of ?

Er
a. Acetaminophen, Aspirin
b. Amphetamines
c. Morphine

I
d. Atropine, Strychnine, Quinine

• Weak acidic drugs • Weak basic drugs

Forced
I
Alleline Blurs
yAuditor's
Forced
sodium mate Ammmiumcloride
Q. pK values means:

a) pH at which a drug is 100% non-ionized

I
b) pH at which a drug is 50% non-ionized and 50% ionized
c) Conc. at which a drug is produce 50% of maximum effect
d) Conc. at which a drug is occupies 50% of receptors
Q 2. Which of the following drug is NOT used as transdermal patch?

a) Promethazine
b) Diphenhydramine
c) Clonidine
d) Hyoscine

6
 Transdermal Patch Indication

Nicotine patch
Smoking Cessation
Hyoscine (Scopolamine),
Motionsickness
Diphenhydramine

Nitrates
Post.es n Etm
ChronicAngina
Clonidine HM
Rivastigmine
a
Alzheimer Dreese

Rotigotine Parkinson Disease

Q. Incorrect match regarding the Drug and Antidote combination

a) Acetaminophen: N Acetyl cysteine

b) Digoxin: Digifab
I
c) Amfetamine: Sodium bicarbonate

t
d) Diazepam: Flumazenil

8
 Drug Antidote
Amphetamine
Ammonium Chloride
Tricyclic Antidepressant (Imipramine)
Sodium Bicarbonate

Organophosphate and Carbamate

atropine
togging
IM
Atropine (belladona, datura poisoning)
Physoselamine carbamate

CCB (Verapamil)
Calcium
gluconate
Propranolol (Beta blockers)
Glucagon Tachyage
Bradycardia
 Drug Antidote
Digoxin

Diazepam Beer20deaUp1m
Died.mn qaitpigi
FLUMAZENIL
ZEPAM
Methanol , Ethylene glycol
FOMEPIZOLE
Lignocaine, Bupivacaine
A Intra lipid emulsion
201
Aspirin
Sodium Bicarbonate
Paracetamol
wf repaint
nightlight
EI E
Morphine (opioids)
Q: A lady with hypomania / BPD wants to conceive. Most teratogenic drug is:

A. Lithium Len Fagen c

D
B. Valproate mostteratogenic
C. Olanzapine

D. Carbamazepine
Q. A 35-year-old chronic hypertensive woman visits the outpatient department
for pre-conception counselling. Which of the following anti-hypertensives should
she discontinue?
A- Labetalol
B- Nifedipine
C- Telmisartan
D- Alpha methyldopa
 PREGNANCY
Disease Drug of choice Contraindicated

Epilepsy
Levetiracetains Lamotrigine VALPROATE
Do notstop AED in
pregnancy

Bipolar disorder VALPROATE

Antipsychotics

Hypertension LABETALOL DOC ACE inhibitor ARB

Hydralazene t
Pln
Preeclampsia Methyldopa PII SARIN
q 13
 PREGNANCY
Disease Drug of choice Contraindicated

Hyperthyroidism 1st PTU CABmazole methimazo

Carbimazle
2nd3rd
Meth maze PTI
Anticoagulants WARFARIN 1st
Heparins Minh
Ulman 12weeks

Antibiotics Penicillin Fo
Aminoglycosides
Cephalosporin
Macrolides Erythromycin Tetracycline
Sulfonamide 14
 my
Teratogenic dugs

Thalidomide a
Fea ftp.wm
Lithium

ACE inhibitors/ARB
IEBEmomgygUshaped Boat
PRIL SARAH RenyAgeness
Carbimazole
Methimazole s

Valproate,
Methotrexate to
MOBlossyndhmed
y
Misoprostol

6th cranial never

Q. In which route a drug undergoes first pass metabolism in liver ?

a) Topical

a
b) Oral
c) Sublingual
d) Intramuscular

16
Oral route

OF one
sestina
am

i
I
First pass metabolism in Liver

17
Q: How to bypass FPM of liver ?
Ans: By rest all other systemic routes (except oral)

gl NITRATE AcuteAngina
Abortion
Sublingual SIL Misoprostol

ExternalHemmishoidalvees Rectal Diazepam

egg t
Rectal I ive
Tesillesecures
g
18
Z track technique

Ig
injection
Muswearingenm
Ron dextran
eye Antipsychotics To avoid staining of
siefats tissue

xxx
yay 19
Q. Rate of absorption on conc.-time graph is represented by:

o
a) T-max

b) C-max
marksmen
c) AUC m
i
want
d) C-trough x
 Bioavailability
• FRACTION of drug that reaches systemic circulation in
• UNCHANGED FORM with TIME .

1000 BE
• BA of I.V. Route:

• BA of Rest all other routes:

LIVE
111111
T I
Bioavailability (F) =

not
on E
Q. Hemodialysis is not effective in poisoning of:
a) Phenobarbitone
b) Lithium
c) Aspirin
d) Digoxin d Do hemodialysis No role of hemodialysis
High GEL
Theophylline A Amfetamine
T
A Alcohols Benzodiazepines (Diazepam)
B
B
J
Barbiturates Chloroquine
C
L Lithium Digoxin
D
A Aspirin
Chloroquine Highest 150004mg

BULL's
eyemaculopathy
Retina
A
E

23
Q9. Clopidogrel is a prodrug and is converted to active form by which CYP enzyme ?
a) CYP1A2
b) CYP2C9 CLO
DI
c) CYP2C19
d) CYP2D6
CI

CYP2E1

CYP3A4

24
 Drug interaction

CYP3A4
Estrogen I
inactive Rifampicin
i am
Cisapride d CYP3A4 Cypinhibitor
c Erythromycin/ Ketoconazole
Astemizole Inactive

T
Terfinadine ftp.narp aaapoinm
CYP2C19
Clopidogrel (prodrug) Active Form Omeprazole

II Tomeprazole X
Cypinhibitor

i
Pant Yeastypnsty 25
Q10. A female patient on oral contraceptive pills (OCP) was diagnosed to have
tuberculosis and started on antitubercular therapy (ATT). She was advised to use an
additional barrier method of contraception. What is the reason for this advice?
a) Teratogenic
b) Failure of ATT
c) Rifampicin decreases OCP metabolism
d) Rifampicin induces OCP metabolism and cause failure

If
 Extrahepatic Metabolism

1. Plasma Esterase:
ESMOLOL L LANDIOLOL
10min 4min
BROMELL
shat
Clevichpine CA I
Reenii
fentanyl opioids
2. Plasma Psuedo-Choline Esterase:
stop
Sucarylcholine y invading
3. Hoffman Elimination: ATRAcurium CIS ATRAcurium
spuntanyina atesCt3HEtZraEsterasDC100j.H E
sm

SATI in hyaline 27
Q11. True about first order kinetics is……
a) Half life constant but elimination changes with plasma concentration
b) Elimination constant but half life with plasma concentration
Pure
any
c) Constant amount of a drug is eliminated a.in i
d) Alcohol shows pure first order kinetics
1Phenyt
Isatin
Kenetee
First order kinetics Zero order kinetics
clearance High antony
Elimination4 PM Iconstantott
Elimination

Giz Toutant t.ee plasmacenc

fewDrugs
28
Q12. Maintenance dose of a drug depends on. ?
a) Clearance / plasma concentration
b) Clearance X plasma concentration
c) Clearance X loading dose
d) Volume of distribution X plasma concentration

Ild X
• Loading dose
Target conc
initialdose
• Maintenance dose CL x Target conc
yatautant
aggelimination
0.693
Iq o.gg
• Half life
29
Complete elimination of drug Steady state concentration

I 951 elimination

fast fatty
t Tied tuionsted
amnio
HIII ji

NEE
395µm
nahin
 HIT and Run drugs (suicide inhibitors)

Protease
R leonavir
mensch enzyme ly
Kt ATPase
Omeprazole all PPI Invastle inhibitor II
M AO inhibitor Phenelzine

A SPI Rin irreversible inhibitor COXenzyme

Match the following:
5
23
1. Nicotinic receptors

2. Muscarinic receptors
ma Grogan

3. Insulin receptors

4. Thyroid receptors
fiefdom
Mpteranenkine
Iggy

Intracellular
my
 Inotrophic Receptors GPCR Protein Kinase Receptors Intracellular Receptors
Metabotrophic Receptors

• Nicotinic • Muscarinic Tyrosine Kinase Receptor CYTOPLASMIC:

• 5-HT3 • 5-HT 1 to 7 (except 5-HT3)

• Insulin,
• IGF a
• Vitamin D
• Glucocorticoids
• Mineralocorticoids
• Glutamate (NMDA) • Alpha/beta • Testosterone
• Progesterone
• Histamine JAK-STAT receptors
• GH

I
• Opioid for • Prolactin NUCLEAR:
• Gaba-A • Cytokine • Thyroid receptors
• All Hypothalamic Hormones • Leptin • Vitamin A
• Glycine • PPAR
• All Pituitary Hormones (Except • Estrogen
GH, Prolactin)

• Angiotensin Receptors

• Photoreceptor, Odorant
Q15. Which of the following is an Antagonist ?

FullAgonist

172
4 Partial agonist

Mood Antagonist

g InverseAgonist
 Agonist Competitive Antagonist Non-Competitive antagonist

e CA

f NCA Rightwardshift in
DRI
Downward Shift

Vmax (response) Vmax (response)

K
f8 1
Nochange
Km (dose) Km (dose)

dog
Minoan mage
Dry
Dose response curve
I
signed 35
 W
Lineweaver Burk Plot Reciprocal graphof pre Straighty
a Ling
Competitive antagonist Non-competitive antagonist

• Vmax = • Vmax =
sang
• Km = • Km =

1
CROSA Not
H
Agonist
V
H
Kup Compenta non comp
game ma
1
Conc.
Ez
Q-16. Calculate the therapeutic index of a drug whose dose-response curves are
plotted as shown below:

sagging
A- 1
B- 2

0
C- 4
D- 8

O O w

D 50 Dose lethaleffect in soy people

T1 u
u

EDT Therapy
 Mandatory unbimay Safety M
W 50
1
see It PkHDMI
thine
2 200 500 Matheny
FtI
m
Patients
tYttticagyeym
ProofRCT
of
3 in
sooo go.es Blinding Ggg

MII MARKET
patient rest
ge gaardffipanalwF
4 red patients
ME
unbinding
steam
 Anton
• Phase 1 trial is NOT done for:
Efficacy except in

• RCT + blinded trial Inanely

§ Multi site trial:

§ Most costly:

§ Drug comes into market after:

§ Which phase is done after market approval:
Q. Paracetamol 500 mg when tested actually contained 200 mg is which class of
counterfeit drug:

a) Spurious Falsified Maa t

Lormand
b) Adulterated substandard
Yang Its
c) Adulterated Rate Additional
Harmfulexcipient
d) Unethical

Counterfeit Drugs

40
1. Orphan Drugs for
Drugs
Rarityprevalence is a 1 5 phompulation

prevalent Dreese
2. Essential drugs Drugs for Highly

Available All times All formulation All

doses

costeffective Affordable
4 Neutered ID rugs
Q. Which of the following is Schedule X drug ?
a) Thalidomide
X Drug
b) Enalapril YTeratogenicTaory
c) Telmisartan
d) Ketamine Narcotic psychomphic Schedule X
D
• Schedule G under medicalsupersion
Gen egg Misoprostol
• Schedule H
Prescription DRUG Take thou

• Schedule X Narcotic psychotrophic DRUG

Addiction Asano NB
ANS and Glaucoma
5min Break
Q21. Which of the following is the mechanism of action of botulinum toxin?

I
A- Inhibits the release of acetylcholine o ca s
B- Release of noradrenaline at synaptic cleft
C- Selectively and irreversibly inhibits nicotinic receptors
D- Stimulates muscarinic and nicotinic receptors
Botulinum toxin Tetanus toxin
MOA: Release
of
ATMgrave
headache
Release GABA glyane
I d
d Muscle spasm
antraction
jMYaniacerde
1 1 5
1. Muscle spasm/rigidity 8
minus

a safe
2. Hyperhidrosis
the
3. Cosmetic wrinkles
BOII
 Receptors of Acetyl Choline

Nicotinic Receptors Muscarinic Receptors

I
NI Nin
Autonomic Neuen stubbolMIe
gangue

Ganglionic Nondepolanzy Blow1

Blog MI
BIT iaelerant
Trimethaphan
 I
Non Depolarizing Muscle relaxant
Bloat
Curare Tuso curare pod Revend TAI
Curium Arawnum
cis Yipping
Curonium EWMM
Rocunnium sugamaded
my
Type Periphery Agonist Antagonist Effect
Location

M1 Diarrhea
Stomach
Tna
xxx Keane Urination
Miosis
M2 Bronchospasm
Osman ten i Bradycardia
M3 Excess HCL
Bethany Solefenau
Rest ofBody Lacrimation

II Salivation
Sweating
Q22. Which drug is NOT used for quitting smoking?

a. Varenicline
b. Buspirone

fxx
c. Nicotine patch
d. Bupropion
 SMOKING DE-ADDICTION
First line drugs
intine Transdermal
Nicotine Gums Most Effective Drug
I
my
G Lounges
spray asal
r
try
Varenicline
Pmhdgmt p Karenina
Nicotinic rapt depmin suing
my
Bupropion NDR
CMSDos seizures
Anhayomant
cus Dis
Ching
Q. Drug used in diagnosis of myasthenia gravis
O
a) Atropine
b) Tubocurare
c) Physostigmine
d) Edrophonium

Aminoglycosides BioaI
Beta Blow
Curare
Myasthenia gravis AI Dis Antibodies BlockND
Muscleweakness
me Ptosis
Symptomatic Treatment Pyridostymine
Muscleweakness
0571921 pay
Definitive Treatment
RemoveAntisodes

Myasthenic Crisis
Preying
Azathioprine
mama Jeux
TensionThymeamy

Plasmapheresis
Resp
Fim II one
Diagnosis
EDrophopium Man improvement
in Ptosis Edrophonio

TENSIFT
 Neurotoxic
Q24. A patient with history of snake bite (COBRA, Krait) presented in emergency
with symptoms of fatigue and irritability. Ten vials of antivenom were administered
intravenously but the patient is still having difficulty in swallowing, ptosis and
respiratory distress. What should be the next line of management?

comment Polyvalent
A
a) Atropine and neostigmine
b) Nebulizer with salbutamol
c) IV hydrocortisone
venom nontoxic
d X Antinomy
d) Antihistamines
Blythe
Xue paralysis

Anping
Nustigmine
Q25. Drug not used in Alzheimer’s disease

Amine NHy watersoluble

D
a) Neostigmine
Quarternay
I
b) Donepezil
crossBBB
Do not
c) Aducanumab
d) Memantine
Drugs for Alzheimer’s disease (dementia)
Anti choline Esterase Tertiary Amine N
Tacrine
I Banned Hepatotoxic A Ach in Brain
Donepezil Amemory
D

G
Galantamine nun Benzgalantamine den Git S E

RD
Rivastigmine Transdermalpatch MGwDr
to
Anhbody against13 Amy
IFucanum ABQ
in A
memory agony Labeau LECANEMAB
Disease DONANEMAB
Memantine NMDA Antagonist
Q26. A patient presents to the emergency department with diarrhea, sweating, excessive

Brat
lacrimation, and salivation. His pulse rate is 55/min and his plasma cholinesterase level was
low. Which of the following can be used to treat this patient?

DUMBBELLS Antichyling
a. Neostigmine TAU
b. Atropine
v
c. Epinephrine Essanay
d. Benztropine
D
U YE
Diarrhea
Urination
Treatment FARMERS
M Miosis Pinpomptupu Organo-Phosphate Carbamate poisoning
B Brochospasm poisoning
B Bradycardia Malathion, Parathion Aldicarb
E Excite/Seizures

gimme
L Lacrymation TIK-20 Carbaryl
S Salivation
S Sweating Tabun, Sarin Soman

Reactivate
a
Oximes
i y
Atropine poisoning BlockAchreceptor
d

DUMBBELL
Opposite
of
Hot as hare

Red as Beat
Ay
Hyperthermia

Flushing
D sweating
skin DATURA PLANT

Belladonna plan
upon shed
Dry as bone Dry eyes/dry mouth pop Paysostigming BBB
Ah
Blind as Bat
F
Mydriasis and Cycloplegia Lens Loss accomodan
of mortyming
Mad as hatter Delirium and seizures hmmm not
X BBB
Constipation, Urinary retention, tachycardia
y
Anticholinergics
1. Cortex If
Hyoscine I
scopolamine
memory cognition sedation

us
Block p Truths Manthey

DOD Thiopentone
2. Basal ganglia Benzhexol
Benztropine DRUGinduced
Biperiden
Bloch Panamint
Promethazine
Q27. False about motion sickness

a) Anti-emetics should be taken when nausea/vomiting starts

b) Hyoscine and Diphenhydramine patch can be applied on post auricular area
c) 1st generation anti-histaminics are more effective than 2nd generation
d) Anti-emetics produce sedation as adverse efffect
3. Vestibule (inner ear) Drugs for Motion sickness
mannnn OTL • Hyoscine (Scopolamine)
Ty
oo

Mfs reinsya É
NAusee
•
•
•
•
•
Diphenhydramine
Promethazine
Cyclizine
Meclizine
Cinnarizine
Éj ÉÉÉ
GoseBBB

rang 1 promo
30 min before
Alleat
Morning sickness Msd Ents meas
journey
Hanchey in 1st pregnancy
Dff Demme Pyridoxine
Mountain sickness
Resp m Annand
 I 4
4. Heart Atropine DoD Bradycandy
All nude Block
BIGyay no
1
not effective in Transplanted Heart
dilators
Broncho
inhale
5. Respiratory tract Glycopyrrolate
I Ipratropium shortest
Block M3 3
Tiotropium

1 ayyy
O

I
Ingest
Umeclidinium
Aclidinium

1 Richof Aspiration
Asthma
 tremor
6. Urinary bladder midygmanopine
Blood Oxybutinin
Overactive
Flavoxalate
den Bladder
Debunk
Fesoterodine
d
L Trospium/Tolterodine
Do notcross
BBB
Étract Solefenacin

perussw
school

Days
Darefenacin face tendency
Pruned Alzheimer
Is
X
7. Stomach Pirenzepine
Telenzepine
now M
lutea Pepticuly
Adrenergic drugs

Endogenous Catecholamines
D Dopamine
Nor Adrenaline
N
I nor epi
A Adrenaline Epinephrine
Q. Catecholamines are synthesized from which amino acid?

a. Tyrosine

b. Tryptophan

c. Glycine

d. Arginine
 Tyrosine
Catecholamine
synthesis Tyrosine hydroxylase

I DOPA Xgimenstep
DOPA decarboxylase QQ
CARBIDOM TX DOPAMINE

Magog
Nor epinephrine
X

spiking
Epinephrine

4
RELEASE

Post synaptic organs

Q28. What dose of Epinephrine is used anaphylactic shock?

a. 1:10000 I.V. - 1ml

CPR cardiac arrest
1,000
b. 1:1000 Intraosseous 1 ml Is
t
c. 1:1000 I.M. – 0.5 ml
Anaphylaxis
d. 1: 5 lakhs
alonge
 Shock Drug of choice
Septic shock

Ime
Neurogenic shock

Cardiogenic shock with Hypotension

d
Cardiogenic shock without Hypotension
Ts
Cardiogenic shock with oligouria

Anaphylactic shock
ARF
Dopamine
t.JP Stress ECHO

Cardiac arrest (CPR)

Resistant shock
I Epi
VASOPRESSIN
 Non-catecholamines BY
y
1. Vasopressors
Is I n
yasoconsmmm
• Hypotension in Pregnancy 9 EPHEDRINE
• Hypotension in spinal anesthesia 8 ephrin
Phenyl
e

• Postural hypotension Mido brine Q

2. Mydriatic Phenylephrine X Agonist
contractmedial
Active Myanasis

Ah m
s it m

Anhmuscarinic Blockm Paraffin

Atropine Ij ointment I
Passive
C Cyclopentolate
Tropicamide Fondoscopy Mydriasis
T
Homatropine in children
H
3. Nasal decongestants in note
if
Oxymetazoline
thinning
Xylometazoline use
Continuity of
I
Ephedrine Atrophic Rhinitis
Pseudoephedrine
Sudden stoppage
of
I Rebound

MRhinnahes

Receding
4. Tocolytics Relax uterus
Pretenders
Atosiban Oxytocin Antagonist
Safe in
Heart
Beta 2 Agonist RITODRINE Disease

CCB
Nifedyne
 a
5. Beta-3 agonist Mirabegron

L
Vebegron
DampedME
In Newbies
Overactive Bladder
Attention Deficit Hyperkinetic Disorder (ADHD)

É Imm

IET
DO NDRi _ADMD Ti
d
SETHYPMM ATOMOXETINE
Amffin tics
synd
Tourette
Narcolepsy sudden Daytime sleep im Acecleats

1
MODAFINIL DOD
TIPROLISAnt PITOUSAND inverse Agonest
Hz receptor
SURI AMATOL IRI f
 Drug BP Net heart rate
c TBp
ne
Nor Epinephrine

a
not
p
Tg

T.im
Epinephrine

PL
f

HD ABP
st ii

put
Vasomotor reversal of Dale
Edit arts BP
Vp xp to
unoppudfall in
Alpha-2a agonist It sympathetic Presynaptic neurons

C Clonidine
IIT never stop amide suddenly
1 g Release
Rebound him Nor-epinephrine

mtLzm.manIzae
A
Éhjen
Alpha methyl dopa
MY

La Timothy BTEngerose
www.mmdqqxgg py coomsst
HM in pregnant Post synaptic receptors
 Non selective alpha blockers 4 Block

Hypertension in pheochromocytoma PHENOXYBEN amine

go

Clonidine rebound hypertension

PHENTOLAMINE

Cheese reaction Hypertension

a

MAO inhibitor
Y
Tyramine
Vasodilator during Angiographies
Toutzoline
 Selective alpha-1 blockers

Prazosin osin Tamsulosin

I
Terazosin
f
Sidodosin

Doxazosin Bent His

BPI
In
Alfuzosin

XX
i
 Benign Prostrate Hypertrophy (BPH)

1. Open Ureteric sphincter 2. Reduce prostrate size

Relieve Urinary obstruction t

Be 52 Reductase
inhibitor

Tamsulosin A
II 00 winged
Ten Dihydro
NODOSE Testosterone

IBM 1

sIImpotenee Fineim Tpromat

 ing
Q31. Drug of choice to control hypertensin and pulmonary edema in scorpion sting
mum
a) Epinephrine
b) Prazosin
c) Tamsulosin
d) Dexmeditomidine
 Scorpion sting

Antidote Venomd

AI
HM Pulmeduna Infshoca
ÉHyF

T t
PRAWI Eprn Adrenaline
 Beta blockers
1st generation 2nd generation 3rd generation
Nonselective
BB I cardiosilictun

Pyari
Bi Ba Bs
Propranolol
I Bi
B
PYP
Bisoprolol
I speadpropity

So
SOTHOWL E
Vasodilator
v Emolol
T
Timolol a A acebutolol
N NADOLOL M metopolol
A Aterolow
A m
 Vasodilatory action of 3rd Gen. Beta Blockers
Produce
Nitric Oxide Calcium blocker Alpha blocker K+ opener

t t
Betanowl LABEMOL This OWL

Jyj
o
combined
Blocker
xp
app
Block
Block
Alpha Antioxidant
Reduce oxidate
Nesivolol
 I

Longest: NADOLOL Shortest: LANDIOLOL Esmolo

Open K+ channel: TILL SOUL Close K+ channel: SOTALOL

OT prolong Terada
Of
pointy
Partial agonist Local anesthetic effect
Adv No Trap
Pindolol Bo I Block Naechannel
Lynocain
Pindowy
I Acesutolol Propranolol
Q32. Propranolol is drug of choice for:

a. Infantile hemangioma
DE
b. Diabetes mellitus
c. Asthma
d. Pyogenic granuloma
Propranolol

I
Anxiety

conversing
Q33. Which of the following side effects are likely to be observed when a patient already
taking metoprolol is prescribed verapamil?

as
IT
a. Bradycardia with AV block
b. Torsades de points
c. Tachycardia
d. Ventricular fibrillation
 Adverse effect of beta blocker - BARD
Due to Beta-1 Blockage Due to Beta-2 Blockage

B
radyterdee AMBI A sinma X
R
Aynaud's

anolol
• Non-selective BB
I DIABetis mullets

• Cardio-selective BB

pry
Metoprolol Atenolol
Beta blocker are never combined with: VERAPAMIL DILT AM

LAMB radylaude

Beta blocker toxicity antidote:

Glucagon

Beta blocker in diabetes mellitus: unawareness

Hypoglycemic
BAD
mask symptoms
of hypoglycemic
Q34.Which of the following antiglaucoma medications is avoided in diabetic cystoid
macular edema ?

a) Timolol
b) Brimonidine
4 Retinalinflammation
É
c) Latanoprost
d) Dorzolamide
DRUGS FOR GLAUCOMA

I • PG F2 alpha P unusual outflow

gaffer
• Pilocarpine teaser aye
j

e•
De
• Alpha agonist

• Beta blockers

Carbonic anhydrase inhibitors

It pro drum of
from alien process
Drugs of choice for Glaucoma

• Primary Open angle Glaucoma PGFza Latanoprost Bimatoprost

• Angle closure Glaucoma

PEEL
• Acute Congestive Glaucoma
if Acetazlamide
Fugett Mannitol
 PG F2 alpha we
edeme
• Latanoprost a
• Bimatoprost
men
II I Eterouromia
Interior
Horrid
may IRIDI

is oT
Glaucoma: One liners
I
• Allergic blepharoconjunctivitis (maximum)
APRALeonidux
• Painful eye drops

F P
• Bronchospasm (Avoid in asthma)
Ls
B Blocker
angina
Timolol BetaxoloD ÉÉ
• Avoid in Children
spam
• Causes Secondary angle closure glaucoma
Faction 41 Bnmoning
CA inhibitor Dorzolaming

C4Y
• Dark/black eye Brinzolamia • But safest in Pregnancy

Is DIPIVEARIN prodry
CAMIEpinephrine m
Black
Q35.Which of the following antiglaucoma medications is unsafe in infants?

a) Timolol
b) Brimonidine
c) Latanoprost
Apnea sad
d) Dorzolamide
Respiratory system
Q. Which of the following is NOT a side effect of salbutamol?

a. Tachycardia
b. Tolerance
c. Hypokalemia
T
H
I
d. Hypoglycemia
T T H
Hyperglycemia
Tremors Tachycardia Hypoke

É Pi Be
aI q
ANTI-ASTHMA DRUGS
Bronchodilators Anti-inflammatory
G Acute asthma
G Chronic asthma Pont
Seasonal/exercise induced asthma
Mast cell stabilizers
Chongoglycate
Beta – 2agonist B neuronal
Anticholinergics A Lipoxygenase inhibitors
ZILEV Ton
Theophylline T Leukotriene receptor antagonist LUKAST
Monte
Magnesium sulphate Man Corticosteroids Zafer

Monoclonal antibodies
Monoclonal Antibodies In Asthma GINAN guideline
Omalizumab Block
Mepolizumab
IgE Asthma
Bloch 12 5 arcuate
Reslizumab
I mopiedemeth

urticaria
Benralizumab Bloch 12 5 receptor

Dupilumab Block 12 4 receptor

ongoing
stromal hymphoteen
Tezepelumab Blochthymic
 SPECIFIC BETA-2 AGONIST: Bronchodilators

shinny
JAM Indacterol
Salbutamol SAemterol

Terbutalip
aim
Idf
Baensated
oomf
I
Banned
Bikini anasound
Asthma
Q38. Main mechanism of theophylline in asthma is Teased
a) PDE 4 inhibition
b) Adenosine A1 antagonism
IF A
c) Calcium blocker
d) Histone acetylationY F
w g gym
citomilast
IBUDILAY
Theophylline Toxicity
Tim
E
S •
D
Seizure

3
Adenosine Ai Bloch
u •
0
Urination

A •

•
Arrhythmia M
GIT upset (dyspepsia)
from
J PDE inhibition
•
I
Headache
 Magnesium sulphate
Uses
•

•
T OR BAD Es de
Antacid
pointy Beni
• Earliest sign of Magnesium toxicity

my
• B ARI UM
L
Toxicity ampasiett
Tree
je
ch
Martians
•

• E CLAM
psi a Bloodduels
• STATUS Asthmatics Month I duds
urinary Mg
Q39. Drug producing below adverse effect is

a) Fluticasone
Y ire
b) Salbutamol
c) Ipratropium WHITE fungus
d) Zileuton
4
candid s

oralthusly
Q. Continuous Nitric Oxide inhalation is used for

IE
a) General anesthetic
b) Pulmonary artery hypertension
c) Laparoscopic surgery
d) Homocystenemia
 DRUGS FOR PAH vasodilator
D PG I 2
D TREPRISTINOL ILIPROST EPOPROSTINPOCO
Endothelin antagonist BOSENTAN ETB pay
E f Ewan YAMBRISEMIETA

Dimatteo
PDE 5 inhibitor
WED
Soluble Guanylyl Cyclase activator
S RIOCII DI
ng
I2 PG agonist
g Erectile
SELEX PAG
pysfund
Continuous NO inhalation
Coa QQ
CCB
 Bo
Q40. A patient presents with a cough and thick sputum. What should be the drug

IT
given to this patient?

a. Bromhexine
b. Codeine Expel
out mucous
c. Dextromethorphan
d. Noscapine
t
Expectorant
 Drugs for Cough
nocough
1. Expectorants Productive 2. Anti-tussive supren
centm
infectivecough cough
pry non infected
• A mp oÉo •D
Allergiccoup
Extromethorphas
NMDAAntz
•B •O

typodslodd
Manne
morphine
•C •N
YSTENE N Acetyloyster
CARBOcysteine
Ioscapine
Addictive
Erdocysteine