ILOILO DOCTORS’ COLLEGE
COLLEGE OF NURSING
West Avenue, Molo, Iloilo City
Sepaya, Mary Mitzi 3E
Amoxicillin (Cefuroxime)
Drug Study
Drug Name Classification and Indications and Side Effects and Adverse Special Precautions Nursing Responsibilities
Mechanism of Action Contraindications Effects
Classification: Indications: Side Effects: ● Use cautiously in ● Assess for
● Generic Name: Antibiotic patients with renal infection signs and
Cefuroxime (Second-generation ● Respiratory tract ● Gastrointestinal: impairment; dosage obtain cultures
cephalosporin) infections (e.g., nausea, vomiting, adjustment may be before starting
● Trade/Brand pneumonia, diarrhea, needed. therapy.
Name: Zinacef (or bronchitis) abdominal pain ● Monitor for
Ceftin, commonly Action: ● Urinary tract ● Headache ● Monitor for signs allergic reactions,
known in the Cefuroxime inhibits infections ● Rash or pruritus of allergic especially after the
Philippines) bacterial cell wall ● Skin and soft (itching) reactions, first dose.
synthesis by binding tissue infections especially in ● Instruct patients to
● Dosage: 500 to penicillin-binding ● Otitis media patients with a complete the entire
mg/tablet (or as proteins (PBPs), (middle ear Adverse Effects: history of penicillin course of
prescribed) causing cell lysis and infection) allergy. antibiotics even if
death. It is effective ● Sinusitis ● Pseudomembranou they feel better.
● Route: Oral or IV against both ● Gonorrhea s colitis (rare) ● Prolonged use may ● Educate patients to
(depending on the Gram-positive and ● Stevens-Johnson result in report severe
formulation) Gram-negative syndrome (rare) superinfection, diarrhea or signs of
bacteria. Contraindications: ● Anaphylaxis (rare including fungal superinfection.
● Frequency and but serious) infections. ● Administer oral
Timing: BID ● Hypersensitivity doses with or after
(twice a day) for to cephalosporins ● Monitor renal food to improve
oral; as prescribed or penicillins function in patients absorption and
for IV ● Caution in receiving high reduce
patients with doses or prolonged gastrointestinal
renal impairment therapy. upset.
ILOILO DOCTORS’ COLLEGE
COLLEGE OF NURSING
West Avenue, Molo, Iloilo City